Class information for:
Level 1: DIHYDROFOLATE REDUCTASE//HYDROGEN TUNNELING//PROMOTING VIBRATION

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
6999 1342 43.2 64%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
1587 6631 FOLATE RECEPTOR//REDUCED FOLATE CARRIER//DIHYDROFOLATE REDUCTASE

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 DIHYDROFOLATE REDUCTASE Author keyword 28 21% 9% 119
2 HYDROGEN TUNNELING Author keyword 13 58% 1% 15
3 PROMOTING VIBRATION Author keyword 12 86% 0% 6
4 HYDROGEN TUNNELLING Author keyword 6 53% 1% 8
5 LABELED NICOTINAMIDE Author keyword 6 100% 0% 4
6 ENZYME DYNAMICS Author keyword 5 30% 1% 14
7 PROMOTING VIBRATIONS Author keyword 4 75% 0% 3
8 10065 BARNES CANYON RD Address 3 100% 0% 3
9 ROLE OF FLEXIBLE LOOP Author keyword 3 100% 0% 3
10 COMPUTAT MOL BIOL DRUG DESIGN GRP Address 3 45% 0% 5

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 DIHYDROFOLATE REDUCTASE 28 21% 9% 119 Search DIHYDROFOLATE+REDUCTASE Search DIHYDROFOLATE+REDUCTASE
2 HYDROGEN TUNNELING 13 58% 1% 15 Search HYDROGEN+TUNNELING Search HYDROGEN+TUNNELING
3 PROMOTING VIBRATION 12 86% 0% 6 Search PROMOTING+VIBRATION Search PROMOTING+VIBRATION
4 HYDROGEN TUNNELLING 6 53% 1% 8 Search HYDROGEN+TUNNELLING Search HYDROGEN+TUNNELLING
5 LABELED NICOTINAMIDE 6 100% 0% 4 Search LABELED+NICOTINAMIDE Search LABELED+NICOTINAMIDE
6 ENZYME DYNAMICS 5 30% 1% 14 Search ENZYME+DYNAMICS Search ENZYME+DYNAMICS
7 PROMOTING VIBRATIONS 4 75% 0% 3 Search PROMOTING+VIBRATIONS Search PROMOTING+VIBRATIONS
8 ROLE OF FLEXIBLE LOOP 3 100% 0% 3 Search ROLE+OF+FLEXIBLE+LOOP Search ROLE+OF+FLEXIBLE+LOOP
9 KINETIC ISOTOPE EFFECT 3 11% 2% 27 Search KINETIC+ISOTOPE+EFFECT Search KINETIC+ISOTOPE+EFFECT
10 H TUNNELING 3 50% 0% 4 Search H+TUNNELING Search H+TUNNELING

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 HYDRIDE TRANSFER 46 24% 12% 167
2 DISTAL MUTATIONS 42 78% 2% 28
3 PROTEIN PROMOTING VIBRATION 41 90% 1% 18
4 DIHYDROFOLATE REDUCTASE CATALYSIS 38 60% 3% 42
5 HYDRIDE TRANSFER STEP 28 81% 1% 17
6 COUPLED MOTION 25 75% 1% 18
7 THERMOPHILIC ALCOHOL DEHYDROGENASE 22 67% 1% 20
8 ENZYME CATALYSIS 21 14% 11% 141
9 COLI DIHYDROFOLATE REDUCTASE 17 28% 4% 51
10 DYNAMIC KNOCKOUT 17 100% 1% 8

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Role of Dynamics in Enzyme Catalysis: Substantial versus Semantic Controversies 2015 4 44 75%
Perspectives on Electrostatics and Conformational Motions in Enzyme Catalysis 2015 3 44 55%
A perspective on enzyme catalysis 2003 520 89 37%
Structure, dynamics, and catalytic function of dihydrofolate reductase 2004 217 59 83%
Protein motions and the activation of the C-H bond catalyzed by dihydrofolate reductase 2014 6 37 86%
The Importance of Ensemble Averaging in Enzyme Kinetics 2015 2 65 63%
At the dawn of the 21st century: Is dynamics the missing link for understanding enzyme catalysis? 2010 144 208 37%
Dynamically Achieved Active Site Precision in Enzyme Catalysis 2015 2 27 59%
Coupled motions in enzyme catalysis 2010 66 60 68%
Relating protein motion to catalysis 2006 294 87 59%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ.
in class
1 10065 BARNES CANYON RD 3 100% 0.2% 3
2 COMPUTAT MOL BIOL DRUG DESIGN GRP 3 45% 0.4% 5
3 SCI TECHNOL BIOCHEM 3 60% 0.2% 3
4 HLTH SCI MED PHARMACOL 1 14% 0.4% 6
5 ABT STRUKTUR FOR 1 50% 0.1% 1
6 BIOCHEM PHARMACOL MED 1 50% 0.1% 1
7 CALIF QUANTITAT SCI 1 50% 0.1% 1
8 GERHMANN S 1 50% 0.1% 1
9 HERAKLION 1 50% 0.1% 1
10 JM WIAME 1 50% 0.1% 1

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000232022 HPPK//DIHYDROPTEROATE SYNTHASE//PYROPHOSPHOKINASE
2 0.0000119774 EXTREMELY LOCALIZED MOLECULAR ORBITALS//ASEP MD//LINK ATOM
3 0.0000108676 THYMIDYLATE SYNTHASE//THYX//DEOXYTUBULOSINE
4 0.0000082036 PROTON TRANSFER COMPOUNDS//DADA ARRAY//DNA RNA NUCLEOBASES
5 0.0000073802 JOURNAL OF MOLECULAR GRAPHICS//SPACE FILLING MOLECULAR MODELS//CPK MODELING
6 0.0000068121 REDUCED FOLATE CARRIER//FOLYLPOLYGLUTAMATE SYNTHETASE//HEREDITARY FOLATE MALABSORPTION
7 0.0000066612 PROTON COUPLED ELECTRON TRANSFER//CYCLIC VOLTABSORPTOMETRY CVA//UNITE MIXTE RECH UNIV 7591
8 0.0000060621 KETOSTEROID ISOMERASE//LOW BARRIER HYDROGEN BONDS//LOW BARRIER HYDROGEN BOND
9 0.0000057384 AB INITIO QUANTUM MECHANICAL//NITROSTYRENE DERIVATIVES//SEMIEMPIRICAL QUANTUM MECHANICAL
10 0.0000049724 NADH MODELS//NADH MODEL//NADPH MODEL