Class information for:
Level 1: COMBRETASTATIN//COMBRETASTATIN A 4//COMBRETASTATINS

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
6660 1385 40.3 83%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
1318 8021 COMBRETASTATIN//STATHMIN//COMBRETASTATIN A 4

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 COMBRETASTATIN Author keyword 207 88% 7% 97
2 COMBRETASTATIN A 4 Author keyword 141 83% 6% 79
3 COMBRETASTATINS Author keyword 60 83% 2% 34
4 ZD6126 Author keyword 42 78% 2% 28
5 VASCULAR DISRUPTING AGENTS Author keyword 40 58% 3% 45
6 VASCULAR DISRUPTING AGENT Author keyword 38 58% 3% 44
7 CA 4 Author keyword 32 88% 1% 15
8 CA4P Author keyword 32 88% 1% 15
9 PHENSTATIN Author keyword 30 100% 1% 12
10 CANC TREATMENT DIAGFREDERICK CANC Address 29 71% 2% 24

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 COMBRETASTATIN 207 88% 7% 97 Search COMBRETASTATIN Search COMBRETASTATIN
2 COMBRETASTATIN A 4 141 83% 6% 79 Search COMBRETASTATIN+A+4 Search COMBRETASTATIN+A+4
3 COMBRETASTATINS 60 83% 2% 34 Search COMBRETASTATINS Search COMBRETASTATINS
4 ZD6126 42 78% 2% 28 Search ZD6126 Search ZD6126
5 VASCULAR DISRUPTING AGENTS 40 58% 3% 45 Search VASCULAR+DISRUPTING+AGENTS Search VASCULAR+DISRUPTING+AGENTS
6 VASCULAR DISRUPTING AGENT 38 58% 3% 44 Search VASCULAR+DISRUPTING+AGENT Search VASCULAR+DISRUPTING+AGENT
7 CA 4 32 88% 1% 15 Search CA+4 Search CA+4
8 CA4P 32 88% 1% 15 Search CA4P Search CA4P
9 PHENSTATIN 30 100% 1% 12 Search PHENSTATIN Search PHENSTATIN
10 COLCHICINE BINDING SITE 29 88% 1% 14 Search COLCHICINE+BINDING+SITE Search COLCHICINE+BINDING+SITE

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 A4 PHOSPHATE 337 96% 8% 108
2 A 4 146 88% 5% 70
3 TARGETING AGENT 135 80% 6% 84
4 ANTIMITOTIC AGENTS 129 54% 12% 166
5 COMBRETASTATIN A 4 116 55% 10% 143
6 A 4 PHOSPHATE 114 87% 4% 55
7 COMBRETASTATIN A 4 ANALOGS 104 81% 5% 63
8 VASCULAR DISRUPTING AGENTS 103 65% 7% 98
9 COMBRETASTATIN A4 PHOSPHATE 88 58% 7% 103
10 A 4 DISODIUM PHOSPHATE 84 80% 4% 52

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Medicinal chemistry of combretastatin A4: Present and future directions 2006 296 96 84%
An Overview of Tubulin Inhibitors That Interact with the Colchicine Binding Site 2012 56 151 62%
Developments of Combretastatin A-4 Derivatives as Anticancer Agents 2011 46 70 90%
The unique characteristics of tumor vasculature and preclinical evidence for its selective disruption by Tumor-Vascular Disrupting Agents 2011 86 128 47%
Disrupting tumour blood vessels 2005 504 146 53%
Vascular disrupting agents 2007 156 96 66%
Biological Potential and Structure-Activity Relationships of Most Recently Developed Vascular Disrupting Agents: An Overview of New Derivatives of Natural Combretastatin A-4 2011 30 92 83%
Microtubule depolymerizing vascular disrupting agents: novel therapeutic agents for oncology and other pathologies 2009 87 90 69%
Vascular disrupting agents in clinical development 2007 135 37 54%
Combretastatin a-4 analogs as anticancer agents 2007 70 110 88%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 CANC TREATMENT DIAGFREDERICK CANC 29 71% 1.7% 24
2 SCREENING TECHNOL BRANCH 21 28% 4.5% 62
3 CANC TREATMENT DIAGNIH 16 34% 2.8% 39
4 DEV THER EUT PROGRAMNIH 14 57% 1.2% 17
5 LP4 9 83% 0.4% 5
6 KIDSCAN S 6 80% 0.3% 4
7 ONCOEMATOL 6 35% 1.1% 15
8 MOL DRUG DESIGN 4 32% 0.8% 11
9 TUMOR MICROCIRCULAT GRP 3 29% 0.7% 10
10 EXPT RADIOBIOL RADIOTHER Y 3 100% 0.2% 3

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000281790 FLAVONE ACETIC ACID//DMXAA//5 6 DIMETHYLXANTHENONE 4 ACETIC ACID
2 0.0000229057 UNITE BIOTECHNOL BIOINGN//RECHUNITE BIOTECHNOL BIOINGN//COLCHICINE BINDING SITE LIGANDS
3 0.0000121218 COLCHICUM AUTUMNALE//COLCHICINOIDS//COLCHICINE
4 0.0000104991 DOLASTATIN 10//DIDEMNIN B//TZT 1027
5 0.0000080144 EPOTHILONES//EPOTHILONE//IXABEPILONE
6 0.0000075772 DINITROANILINES//DINITROANILINE//DRUG EFFICACY IN VIVO
7 0.0000073072 SULOFENUR//LY295501//ARYLSULFONYLIMIDAZOLIDINONE
8 0.0000071828 GRP BIOPHYSSTAT//PROTEIN MICROTUBULES//TUBULIN RINGS
9 0.0000069533 HEMATOL ONCOLWINSHIP CANC//MICROTUBULE ACTIVE DRUGS//PHARMACOLRAMMELKAMP EDUC
10 0.0000068310 CI 980//CATALYTIC H 3 HYDROGENOLYSIS//CHENGDU DIAO PHARMACEUT GRP