Class information for:
Level 1: CACO 2//SINGLE PASS INTESTINAL PERFUSION//INTESTINAL PERFUSION

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
6268 1442 36.8 76%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
1981 5091 PEPT1//PEPT2//HPEPT1

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 CACO 2 Author keyword 33 16% 13% 193
2 SINGLE PASS INTESTINAL PERFUSION Author keyword 13 62% 1% 13
3 INTESTINAL PERFUSION Author keyword 12 35% 2% 29
4 DRUG ABSORPTION Author keyword 11 19% 4% 53
5 TALINOLOL Author keyword 10 40% 1% 20
6 BIOPHARMACEUTICS CLASSIFICATION SYSTEM Author keyword 7 27% 2% 23
7 ABSORPTIVE CLEARANCE Author keyword 6 80% 0% 4
8 HUMAN INTESTINAL PERMEABILITY Author keyword 6 71% 0% 5
9 BIOPHARMACEUTIC CLASSIFICATION SYSTEM Author keyword 5 63% 0% 5
10 ORAL ABSORPTION Author keyword 5 10% 3% 42

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 CACO 2 33 16% 13% 193 Search CACO+2 Search CACO+2
2 SINGLE PASS INTESTINAL PERFUSION 13 62% 1% 13 Search SINGLE+PASS+INTESTINAL+PERFUSION Search SINGLE+PASS+INTESTINAL+PERFUSION
3 INTESTINAL PERFUSION 12 35% 2% 29 Search INTESTINAL+PERFUSION Search INTESTINAL+PERFUSION
4 DRUG ABSORPTION 11 19% 4% 53 Search DRUG+ABSORPTION Search DRUG+ABSORPTION
5 TALINOLOL 10 40% 1% 20 Search TALINOLOL Search TALINOLOL
6 BIOPHARMACEUTICS CLASSIFICATION SYSTEM 7 27% 2% 23 Search BIOPHARMACEUTICS+CLASSIFICATION+SYSTEM Search BIOPHARMACEUTICS+CLASSIFICATION+SYSTEM
7 ABSORPTIVE CLEARANCE 6 80% 0% 4 Search ABSORPTIVE+CLEARANCE Search ABSORPTIVE+CLEARANCE
8 HUMAN INTESTINAL PERMEABILITY 6 71% 0% 5 Search HUMAN+INTESTINAL+PERMEABILITY Search HUMAN+INTESTINAL+PERMEABILITY
9 BIOPHARMACEUTIC CLASSIFICATION SYSTEM 5 63% 0% 5 Search BIOPHARMACEUTIC+CLASSIFICATION+SYSTEM Search BIOPHARMACEUTIC+CLASSIFICATION+SYSTEM
10 ORAL ABSORPTION 5 10% 3% 42 Search ORAL+ABSORPTION Search ORAL+ABSORPTION

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 DRUG ABSORPTION 41 19% 14% 199
2 PARTITION RELATIONSHIPS 26 100% 1% 11
3 SECRETORY TRANSPORT 22 66% 1% 21
4 LINE CACO 2 22 17% 8% 117
5 SINGLE PASS PERFUSION 18 83% 1% 10
6 DEPENDENT ABSORPTION 16 52% 2% 22
7 TRUE HOMOLOGOUS SERIES 15 82% 1% 9
8 POLARIZED EFFLUX SYSTEM 15 54% 1% 19
9 USSING CHAMBER 15 42% 2% 27
10 REGIONAL JEJUNAL PERFUSION 15 73% 1% 11

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
The Caco-2 cell line as a model of the intestinal barrier: influence of cell and culture-related factors on Caco-2 cell functional characteristics 2005 324 106 45%
Regional intestinal drug permeation: Biopharmaceutics and drug development 2014 9 75 59%
Caco-2 monolayers in experimental and theoretical predictions of drug transport 2001 524 94 53%
In situ perfusion in rodents to explore intestinal drug absorption: Challenges and opportunities 2015 1 135 39%
Human in Vivo Regional Intestinal Permeability: Importance for Pharmaceutical Drug Development 2014 8 96 49%
Variability in Caco-2 and MDCK cell-based intestinal permeability assays 2008 57 91 69%
In vitro models to evaluate the permeability of poorly soluble drug entities: Challenges and perspectives 2012 29 128 47%
The Caco-2 cell monolayer: usefulness and limitations 2008 70 123 50%
Permeability for Intestinal Absorption: Caco-2 Assay and Related Issues 2008 60 58 53%
Caco-2 monolayers in experimental and theoretical predictions of drug transport 2012 20 96 53%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 GRP BIOPHARMACEUT 4 75% 0.2% 3
2 PRECLIN DRUG METAB PHARMACOKINET 4 26% 0.8% 12
3 PRECLIN CANDIDATE SELECT UNIT 3 60% 0.2% 3
4 GUT BARRIER GRP 2 36% 0.3% 5
5 BIOCHEM ENVIRONM CARCINOGENS BIU 2 67% 0.1% 2
6 DMPK SAFETY 2 67% 0.1% 2
7 DRUG DEV PHARMACOKINET PLICAT CRO 2 67% 0.1% 2
8 LEBENSMITTELTOXIKOL 2 67% 0.1% 2
9 PREFORMULAT SCI 2 67% 0.1% 2
10 BIOPHARMACEUT GRP 2 27% 0.5% 7

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000176069 HUMAN INTESTINAL ABSORPTION//PAMPA//LOG BB
2 0.0000169767 DISSOLUTION TECHNOLOGIES//BIORELEVANT MEDIA//BIOWAIVER
3 0.0000166783 PEPT1//PEPT2//HPEPT1
4 0.0000139792 INO 2628 CZ//DOUBLE PEAKS//DISCONTINUOUS ABSORPTION
5 0.0000103453 SODIUM CAPRATE//SUPPOSITORY//ABSORPTION ENHANCER
6 0.0000093301 PROXIMITY ORIENTATION//CYCLIC PRODRUG//ESTERASE SENSITIVE PRODRUGS
7 0.0000090870 CYP3A//COCKTAIL//MECHANISM BASED INHIBITION
8 0.0000081202 SEDDS//SMEDDS//SELF MICROEMULSIFYING DRUG DELIVERY SYSTEM
9 0.0000080853 P GLYCOPROTEIN//C3435T POLYMORPHISM//ABCB1
10 0.0000079375 OATP1B1//SLCO1B1//OATP