Class information for:
Level 1: PRAVASTATIN//HMG COA REDUCTASE INHIBITOR//COMPACTIN

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
6263 1442 32.2 61%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
408 16067 STATINS//EZETIMIBE//SIMVASTATIN

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 PRAVASTATIN Author keyword 9 11% 5% 77
2 HMG COA REDUCTASE INHIBITOR Author keyword 5 10% 3% 44
3 COMPACTIN Author keyword 3 22% 1% 12
4 I DEV Address 2 24% 1% 9
5 ACYL COA CHOLESTERYL ACYLTRANSFERASE Author keyword 2 67% 0% 2
6 FR194738 Author keyword 2 67% 0% 2
7 LIFIBROL Author keyword 2 67% 0% 2
8 LIPOPROTEIN FAMILIES Author keyword 2 67% 0% 2
9 MEVINIC ACID Author keyword 2 67% 0% 2
10 SANDOZ DEV SLOVENIA Address 2 20% 1% 9

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 PRAVASTATIN 9 11% 5% 77 Search PRAVASTATIN Search PRAVASTATIN
2 HMG COA REDUCTASE INHIBITOR 5 10% 3% 44 Search HMG+COA+REDUCTASE+INHIBITOR Search HMG+COA+REDUCTASE+INHIBITOR
3 COMPACTIN 3 22% 1% 12 Search COMPACTIN Search COMPACTIN
4 ACYL COA CHOLESTERYL ACYLTRANSFERASE 2 67% 0% 2 Search ACYL+COA+CHOLESTERYL+ACYLTRANSFERASE Search ACYL+COA+CHOLESTERYL+ACYLTRANSFERASE
5 FR194738 2 67% 0% 2 Search FR194738 Search FR194738
6 LIFIBROL 2 67% 0% 2 Search LIFIBROL Search LIFIBROL
7 LIPOPROTEIN FAMILIES 2 67% 0% 2 Search LIPOPROTEIN+FAMILIES Search LIPOPROTEIN+FAMILIES
8 MEVINIC ACID 2 67% 0% 2 Search MEVINIC+ACID Search MEVINIC+ACID
9 CAS 81131 70 6 1 50% 0% 2 Search CAS+81131+70+6 Search CAS+81131+70+6
10 CTP PHOSPHOCHOLINE CYTIDYLYL TRANSFERASE 1 50% 0% 2 Search CTP++PHOSPHOCHOLINE+CYTIDYLYL+TRANSFERASE Search CTP++PHOSPHOCHOLINE+CYTIDYLYL+TRANSFERASE

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 MEVINOLIN 78 39% 11% 158
2 COMPACTIN 46 49% 5% 68
3 LOVASTATIN MEVINOLIN 31 92% 1% 12
4 GEMFIBROZIL LOVASTATIN THERAPY 27 92% 1% 11
5 HEPTANOIC ACIDS 27 92% 1% 11
6 TISSUE SELECTIVE INHIBITION 26 52% 2% 35
7 CS 514 22 58% 2% 26
8 MEVINIC ACID ANALOGS 15 62% 1% 16
9 CI 981 13 67% 1% 12
10 TISSUE SELECTIVE INHIBITOR 13 48% 1% 20

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
THE DISCOVERY AND DEVELOPMENT OF HMG-COA REDUCTASE INHIBITORS 1992 443 58 66%
Hydrophilicity/lipophilicity: relevance for the pharmacology and clinical effects of HMG-CoA reductase inhibitors 1998 257 64 50%
A historical perspective on the discovery of statins 2010 30 13 62%
Fluvastatin - A review of its pharmacology and use in the management of hypercholesterolaemia 1996 92 83 61%
DRUG-THERAPY - HMG-COA REDUCTASE INHIBITORS FOR TREATMENT OF HYPERCHOLESTEROLEMIA 1988 619 57 60%
Clinical pharmacokinetics of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors 1996 134 133 37%
PHARMACOLOGY OF COMPETITIVE INHIBITORS OF HMG-COA REDUCTASE 1995 170 166 39%
Lovastatin and beyond: The history of the HMG-CoA reductase inhibitors 2003 261 77 30%
SIMVASTATIN - A REVIEW OF ITS PHARMACOLOGICAL PROPERTIES AND THERAPEUTIC POTENTIAL IN HYPERCHOLESTEROLEMIA 1990 146 55 84%
COMPARATIVE-EVALUATION OF THE SAFETY AND EFFICACY OF HMG-COA REDUCTASE INHIBITOR MONOTHERAPY IN THE TREATMENT OF PRIMARY HYPERCHOLESTEROLEMIA 1995 112 81 53%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ.
in class
1 I DEV 2 24% 0.6% 9
2 SANDOZ DEV SLOVENIA 2 20% 0.6% 9
3 ANDRX S INC 1 100% 0.1% 2
4 FERMENTAT S SHINAGAWA KU 1 50% 0.1% 2
5 LEK PHARMACEUT 1 50% 0.1% 2
6 N KARELIA PROJECT 1 50% 0.1% 2
7 SCREENING NEW DRUGS 1 100% 0.1% 2
8 CARDIOVASC METAB DIS CHEM 1 50% 0.1% 1
9 INTERNAL MED MED PHYSIOPATHOL 1 50% 0.1% 1
10 LOUISVILLE METAB ATHEROSCLEROSIS 1 50% 0.1% 1

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000164004 PROBUCOL//AGI 1067//SUCCINOBUCOL
2 0.0000143590 STATIN MYOPATHY//STATIN INTOLERANCE//MYALGIA
3 0.0000135905 FENOFIBRIC ACID//FENOFIBRATE//FIBRATES
4 0.0000131884 LAROPIPRANT//NIACIN//HM74A
5 0.0000126994 PARTIAL ILEAL BYPASS//POSCH//ATHEROGENIC RATIO
6 0.0000116333 ROSUVASTATIN CALCIUM//ATORVASTATIN CALCIUM//EZETIMIBE GLUCURONIDE
7 0.0000101503 FOOD FUS COMPLEX//KARMELLAE//HYPOCHOLESTEROLEMIC PEPTIDE
8 0.0000098400 LIPOPROT UNIT//LIPOPROTEIN KINETICS//OURCE IL KINET ANAL
9 0.0000093773 STATINS//LOW DENSITY LIPOPROTEIN CHOLESTEROL//ATORVASTATIN
10 0.0000086445 OATP1B1//SLCO1B1//OATP