Class information for:
Level 1: VALPROIC ACID//VALPROATE//TRANS 2 EN VALPROATE

Basic class information

ID Publications Average number
of references
Avg. shr. active
ref. in WoS
6131 1461 29.9 61%



Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)



ID, lev.
above
Publications Label for level above
46 30816 EPILEPSY//EPILEPSIA//ANTIEPILEPTIC DRUGS

Terms with highest relevance score



Rank Term Type of term Relevance score
(tfidf)
Class's shr.
of term's tot.
occurrences
Shr. of publ.
in class containing
term
Num. of
publ. in
class
1 VALPROIC ACID Author keyword 45 15% 18% 269
2 VALPROATE Author keyword 27 14% 12% 181
3 TRANS 2 EN VALPROATE Author keyword 18 89% 1% 8
4 VALPROATE ENCEPHALOPATHY Author keyword 9 83% 0% 5
5 2 PROPYL 4 PENTENOIC ACID Author keyword 6 100% 0% 4
6 VALPROIC ACID INTOXICATION Author keyword 6 100% 0% 4
7 VALPROATE METABOLISM Author keyword 4 75% 0% 3
8 SODIUM VALPROATE Author keyword 4 11% 2% 35
9 CLIN CHEM PAEDIAT Address 4 46% 0% 6
10 4 ENE VPA Author keyword 3 100% 0% 3

Web of Science journal categories

Author Key Words



Rank Web of Science journal category Relevance score
(tfidf)
Class's shr.
of term's tot.
occurrences
Shr. of publ.
in class containing
term
Num. of
publ. in
class
LCSH search Wikipedia search
1 VALPROIC ACID 45 15% 18% 269 Search VALPROIC+ACID Search VALPROIC+ACID
2 VALPROATE 27 14% 12% 181 Search VALPROATE Search VALPROATE
3 TRANS 2 EN VALPROATE 18 89% 1% 8 Search TRANS+2+EN+VALPROATE Search TRANS+2+EN+VALPROATE
4 VALPROATE ENCEPHALOPATHY 9 83% 0% 5 Search VALPROATE+ENCEPHALOPATHY Search VALPROATE+ENCEPHALOPATHY
5 2 PROPYL 4 PENTENOIC ACID 6 100% 0% 4 Search 2+PROPYL+4+PENTENOIC+ACID Search 2+PROPYL+4+PENTENOIC+ACID
6 VALPROIC ACID INTOXICATION 6 100% 0% 4 Search VALPROIC+ACID+INTOXICATION Search VALPROIC+ACID+INTOXICATION
7 VALPROATE METABOLISM 4 75% 0% 3 Search VALPROATE+METABOLISM Search VALPROATE+METABOLISM
8 SODIUM VALPROATE 4 11% 2% 35 Search SODIUM+VALPROATE Search SODIUM+VALPROATE
9 4 ENE VPA 3 100% 0% 3 Search 4+ENE+VPA Search 4+ENE+VPA
10 VALPROATE METABOLITES 3 100% 0% 3 Search VALPROATE+METABOLITES Search VALPROATE+METABOLITES

Key Words Plus



Rank Web of Science journal category Relevance score
(tfidf)
Class's shr.
of term's tot.
occurrences
Shr. of publ.
in class containing
term
Num. of
publ. in
class
1 2 NORMAL PROPYL 4 PENTENOIC ACID 73 85% 3% 39
2 SODIUM VALPROATE 53 17% 19% 283
3 HEPATIC FATALITIES 36 83% 1% 20
4 ACID INDUCED HYPERAMMONEMIA 34 93% 1% 13
5 SECONDARY HYPERAMMONEMIA 23 86% 1% 12
6 E 2 PROPYL 2 4 PENTADIENOIC ACID 23 100% 1% 10
7 SERUM CARNITINE 21 57% 2% 25
8 ASYMPTOMATIC HYPERAMMONEMIA 21 85% 1% 11
9 DIPROPYLACETATE 14 100% 0% 7
10 INDUCED HYPERAMMONEMIA 12 40% 2% 23

Journals

Reviews



Title Publ. year Cit. Active references % act. ref.
to same field
Carnitine in the treatment of valproic acid-induced toxicity 2009 63 79 92%
Valproate: A reappraisal of its pharmacodynamic properties and mechanisms of action 1999 298 169 49%
Valproate-induced hyperammonemic encephalopathy: a brief review 2012 12 14 93%
Evidence for a potential protective effect of carnitine-pantothenic acid co-treatment on valproic acid-induced hepatotoxicity 2014 3 48 50%
Science review: Carnitine in the treatment of valproic acid-induced toxicity - what is the evidence? 2005 63 63 89%
Basic pharmacology of valproate - A review after 35 years of clinical use for the treatment of epilepsy 2002 256 131 38%
Valproate-induced hyperammonemic encephalopathy 2006 66 29 72%
The role of carnitine supplementation during valproic acid therapy 2000 65 22 95%
The effects of sodium valproate on the renal function of children with epilepsy 2014 1 30 70%
L-Carnitine for Acute Valproic Acid Overdose: A Systematic Review of Published Cases 2010 14 13 77%

Address terms



Rank Address term Relevance score
(tfidf)
Class's shr.
of term's tot.
occurrences
Shr. of publ.
in class containing
term
Num. of
publ.
in class
1 CLIN CHEM PAEDIAT 4 46% 0.4% 6
2 TOXICOGENOM CONSORTIUM 2 67% 0.1% 2
3 ACUTE POISONING UNIT 1 33% 0.1% 2
4 BEERS MURPHY CLIN NUTR 1 50% 0.1% 1
5 BEREICH HAMATOL ONKOL HAMOSTASEOL 1 50% 0.1% 1
6 BIPOLAR DISORDERS UNITIDIB SCIBERSAM 1 50% 0.1% 1
7 EPILEPSY ENCEPHALOG UNIT 1 50% 0.1% 1
8 GENER ARD 1 50% 0.1% 1
9 GIFU UNIV HOSP 1 50% 0.1% 1
10 HALL PSYCHIAT 1 50% 0.1% 1

Related classes at same level (level 1)



Rank Relatedness score Related classes
1 0.0000151061 CARBAMAZEPINE 10 11 EPOXIDE//FREE PHENYTOIN//R 4PK
2 0.0000089413 GENIUS R//CHARCOAL HEMOPERFUSION//CARBAMAZEPINE INTOXICATION
3 0.0000087810 AUDITORY DISTURBANCE//PERIPHERAL NEUROMUSCULAR FUNCTION//ACUTE FORM
4 0.0000071970 HARVARD NEUROENDOCRINE UNIT//CATAMENIAL EPILEPSY//HYPOSEXUALITY
5 0.0000068901 EXPTL EPILEPSIEFOR//EXPERIMENTAL EPILEPSY MODELS//MODEL NERVOUS SYSTEM
6 0.0000067608 LAMOTRIGINE//FELBAMATE//OXCARBAZEPINE
7 0.0000066940 ANTICONVULSANT ACTIVITY//MES TEST//EPILEPSY BRANCH
8 0.0000062953 EMORY EPILEPSY PROGRAM//KERALA REGISTRY EPILEPSY PREGNANCY//FETAL HYDANTOIN SYNDROME
9 0.0000061766 REYES SYNDROME//REYE SYNDROME//HLTH SCI MED COMPARAT MED
10 0.0000054298 GABAA RECEPTOR CHLORIDE IONOPHORE COMPLEX//CEREBROSPINAL FLUID AND PLASMA LEVELS//FENGABINE