Class information for: |
Basic class information |
| ID | Publications | Average number of references |
Avg. shr. active ref. in WoS |
|---|---|---|---|
| 6016 | 1475 | 46.6 | 92% |
Classes in level above (level 2) |
Terms with highest relevance score |
| Rank | Term | Type of term | Relevance score (tfidf) |
Class's shr. of term's tot. occurrences |
Shr. of publ. in class containing term |
Num. of publ. in class |
|---|---|---|---|---|---|---|
| 1 | INSULIN RECEPTOR SUBSTRATE | Author keyword | 25 | 39% | 3% | 51 |
| 2 | INSULIN RECEPTOR SUBSTRATE 1 | Author keyword | 18 | 26% | 4% | 60 |
| 3 | IRS 1 | Author keyword | 15 | 24% | 4% | 57 |
| 4 | INSULIN RECEPTOR SUBSTRATE 2 | Author keyword | 9 | 40% | 1% | 18 |
| 5 | IRS 3 | Author keyword | 8 | 100% | 0% | 5 |
| 6 | IRS 2 | Author keyword | 7 | 35% | 1% | 17 |
| 7 | INSULIN RECEPTOR SUBSTRATE 1 IRS 1 | Author keyword | 5 | 42% | 1% | 10 |
| 8 | INSULIN SIGNALLING | Author keyword | 5 | 14% | 2% | 31 |
| 9 | INSULIN RECEPTOR SUBSTRATE 4 | Author keyword | 4 | 75% | 0% | 3 |
| 10 | IRS4 | Author keyword | 4 | 75% | 0% | 3 |
Web of Science journal categories |
Author Key Words |
| Rank | Web of Science journal category | Relevance score (tfidf) |
Class's shr. of term's tot. occurrences |
Shr. of publ. in class containing term |
Num. of publ. in class |
LCSH search | Wikipedia search |
|---|---|---|---|---|---|---|---|
| 1 | INSULIN RECEPTOR SUBSTRATE | 25 | 39% | 3% | 51 | Search INSULIN+RECEPTOR+SUBSTRATE | Search INSULIN+RECEPTOR+SUBSTRATE |
| 2 | INSULIN RECEPTOR SUBSTRATE 1 | 18 | 26% | 4% | 60 | Search INSULIN+RECEPTOR+SUBSTRATE+1 | Search INSULIN+RECEPTOR+SUBSTRATE+1 |
| 3 | IRS 1 | 15 | 24% | 4% | 57 | Search IRS+1 | Search IRS+1 |
| 4 | INSULIN RECEPTOR SUBSTRATE 2 | 9 | 40% | 1% | 18 | Search INSULIN+RECEPTOR+SUBSTRATE+2 | Search INSULIN+RECEPTOR+SUBSTRATE+2 |
| 5 | IRS 3 | 8 | 100% | 0% | 5 | Search IRS+3 | Search IRS+3 |
| 6 | IRS 2 | 7 | 35% | 1% | 17 | Search IRS+2 | Search IRS+2 |
| 7 | INSULIN RECEPTOR SUBSTRATE 1 IRS 1 | 5 | 42% | 1% | 10 | Search INSULIN+RECEPTOR+SUBSTRATE+1+IRS+1 | Search INSULIN+RECEPTOR+SUBSTRATE+1+IRS+1 |
| 8 | INSULIN SIGNALLING | 5 | 14% | 2% | 31 | Search INSULIN+SIGNALLING | Search INSULIN+SIGNALLING |
| 9 | INSULIN RECEPTOR SUBSTRATE 4 | 4 | 75% | 0% | 3 | Search INSULIN+RECEPTOR+SUBSTRATE+4 | Search INSULIN+RECEPTOR+SUBSTRATE+4 |
| 10 | IRS4 | 4 | 75% | 0% | 3 | Search IRS4 | Search IRS4 |
Key Words Plus |
| Rank | Web of Science journal category | Relevance score (tfidf) |
Class's shr. of term's tot. occurrences |
Shr. of publ. in class containing term |
Num. of publ. in class |
|---|---|---|---|---|---|
| 1 | IRS 1 | 118 | 48% | 12% | 180 |
| 2 | PHOSPHOTYROSINE PROTEIN | 79 | 64% | 5% | 77 |
| 3 | SERINE THREONINE PHOSPHORYLATION | 57 | 58% | 4% | 66 |
| 4 | RECEPTOR SUBSTRATE 1 | 40 | 18% | 13% | 197 |
| 5 | GLUCOSE TRANSPORTER 4 TRANSLOCATION | 25 | 36% | 4% | 57 |
| 6 | IRS 1 GENE | 19 | 68% | 1% | 17 |
| 7 | RECEPTOR SUBSTRATE FAMILY | 19 | 58% | 1% | 22 |
| 8 | PHOSPHOTYROSINE DEPENDENT INTERACTION | 18 | 53% | 2% | 24 |
| 9 | INSULIN RECEPTOR SUBSTRATE 1 | 18 | 13% | 9% | 134 |
| 10 | CODON 972 POLYMORPHISM | 18 | 89% | 1% | 8 |
Journals |
Reviews |
| Title | Publ. year | Cit. | Active references | % act. ref. to same field |
|---|---|---|---|---|
| Critical nodes in signalling pathways: insights into insulin action | 2006 | 977 | 121 | 32% |
| Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2 | 2012 | 79 | 171 | 46% |
| Insulin signalling and the regulation of glucose and lipid metabolism | 2001 | 1894 | 98 | 29% |
| Phosphorylation of IRS proteins, insulin action, and insulin resistance | 2009 | 151 | 109 | 51% |
| Positive and negative regulation of insulin signaling through IRS-1 phosphorylation | 2005 | 346 | 104 | 47% |
| From mice to men: Insights into the insulin resistance syndromes | 2006 | 297 | 150 | 36% |
| Defects of the insulin receptor substrate (IRS) system in human metabolic disorders | 2001 | 178 | 87 | 87% |
| Insulin-sensitive protein kinases (atypical protein kinase C and protein kinase B/Akt): Actions and defects in obesity and Type II diabetes | 2005 | 99 | 65 | 66% |
| Targeting type 2 diabetes: lessons from a knockout model of insulin receptor substrate 2 | 2014 | 3 | 60 | 48% |
| How insulin receptor substrate proteins regulate the metabolic capacity of the liver - Implications for health and disease | 2008 | 57 | 252 | 41% |
Address terms |
| Rank | Address term | Relevance score (tfidf) |
Class's shr. of term's tot. occurrences |
Shr. of publ. in class containing term |
Num. of publ. in class |
|---|---|---|---|---|---|
| 1 | SERV VAR 151 | 3 | 43% | 0.4% | 6 |
| 2 | MED SCI CYBERJAYA | 3 | 100% | 0.2% | 3 |
| 3 | BIOQUIM BIOL MOL 2 | 3 | 15% | 1.2% | 17 |
| 4 | U145 | 3 | 18% | 0.9% | 13 |
| 5 | CELL REGULATBUNKYO KU | 2 | 44% | 0.3% | 4 |
| 6 | INTERNAL MED ENDOCRINOL METAB PATHOBIOCHEM | 2 | 67% | 0.1% | 2 |
| 7 | PROGRAM BIOMED BIOL SCI | 2 | 40% | 0.3% | 4 |
| 8 | U568 | 2 | 21% | 0.5% | 8 |
| 9 | HYPERTENS ENDOCRINE BRANCH | 2 | 18% | 0.6% | 9 |
| 10 | CHILDRENS HOSP BOSTON ENDOCRINOL | 1 | 50% | 0.1% | 2 |
Related classes at same level (level 1) |
| Rank | Relatedness score | Related classes |
|---|---|---|
| 1 | 0.0000259586 | BIOL CHEMBUNKYO KU//DEMETHOXYVIRIDIN//2 4 MORPHOLINYL 8 PHENYLCHROMONE |
| 2 | 0.0000198738 | C PEPTICLE//CLIN PHYSIOL METAB UNIT//HENRY WELLCOME S EGRATED CELL SIGNALLING |
| 3 | 0.0000191291 | SERV VAR 151//VAR 151//GONDA DIAGNOST |
| 4 | 0.0000138620 | LEPRECHAUNISM//INSULIN RECEPTOR//DONOHUE SYNDROME |
| 5 | 0.0000115598 | GLUT 4//GLUCOSE TRANSPORT//EPITROCHLEARIS |
| 6 | 0.0000108876 | H 411E CELLS//JIANG TANG KE LI JTKL//ADIPOCYTE SECRETED FACTORS |
| 7 | 0.0000106857 | P66SHC//SHC//SHC FAMILY |
| 8 | 0.0000106589 | GRB7//GRB14//GRB10 |
| 9 | 0.0000096371 | GLUCOSE TRANSPORTER//GLUT4//GLUT1 |
| 10 | 0.0000073316 | IGF 1R//INSULIN LIKE GROWTH FACTOR 1 RECEPTOR//IGF IR |