Class information for:
Level 1: HUMAN INTESTINAL ABSORPTION//PAMPA//LOG BB

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
5963 1482 42.7 73%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
825 11237 JOURNAL OF CHEMICAL INFORMATION AND MODELING//B IT//JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 HUMAN INTESTINAL ABSORPTION Author keyword 23 70% 1% 19
2 PAMPA Author keyword 22 38% 3% 47
3 LOG BB Author keyword 20 100% 1% 9
4 BLOOD BRAIN PARTITION COEFFICIENT Author keyword 9 83% 0% 5
5 LIGAND EFFICIENCY INDICES Author keyword 9 83% 0% 5
6 LOGBB Author keyword 9 67% 1% 8
7 ADME Author keyword 9 14% 4% 57
8 AQUEOUS SOLUBILITY Author keyword 8 18% 3% 41
9 BLOOD BRAIN PARTITIONING Author keyword 8 100% 0% 5
10 CSC MED CHEM Address 6 80% 0% 4

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 HUMAN INTESTINAL ABSORPTION 23 70% 1% 19 Search HUMAN+INTESTINAL+ABSORPTION Search HUMAN+INTESTINAL+ABSORPTION
2 PAMPA 22 38% 3% 47 Search PAMPA Search PAMPA
3 LOG BB 20 100% 1% 9 Search LOG+BB Search LOG+BB
4 BLOOD BRAIN PARTITION COEFFICIENT 9 83% 0% 5 Search BLOOD+BRAIN+PARTITION+COEFFICIENT Search BLOOD+BRAIN+PARTITION+COEFFICIENT
5 LIGAND EFFICIENCY INDICES 9 83% 0% 5 Search LIGAND+EFFICIENCY+INDICES Search LIGAND+EFFICIENCY+INDICES
6 LOGBB 9 67% 1% 8 Search LOGBB Search LOGBB
7 ADME 9 14% 4% 57 Search ADME Search ADME
8 AQUEOUS SOLUBILITY 8 18% 3% 41 Search AQUEOUS+SOLUBILITY Search AQUEOUS+SOLUBILITY
9 BLOOD BRAIN PARTITIONING 8 100% 0% 5 Search BLOOD+BRAIN+PARTITIONING Search BLOOD+BRAIN+PARTITIONING
10 ARTIFICIAL MEMBRANE 6 28% 1% 18 Search ARTIFICIAL+MEMBRANE Search ARTIFICIAL+MEMBRANE

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 PLS STATISTICS 54 83% 2% 30
2 POLAR MOLECULAR SURFACE 46 53% 4% 62
3 ADME EVALUATION 43 62% 3% 45
4 AQUEOUS SOLUBILITY 42 22% 11% 166
5 CACO 2 CELL PERMEABILITY 42 70% 2% 35
6 HUMAN INTESTINAL ABSORPTION 40 49% 4% 59
7 MOLECULAR SURFACE PROPERTIES 38 51% 4% 52
8 MOLSURF PARAMETRIZATION 33 83% 1% 19
9 IN SILICO PREDICTION 28 35% 5% 67
10 PERMEATION ASSAY 27 66% 2% 25

Journals

Reviews


Title Publ. year Cit. Active
references		 % act. ref.
to same field
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings 2001 2793 40 30%
The impact of aromatic ring count on compound developability - are too many aromatic rings a liability in drug design? 2009 151 19 63%
ADMET in silico modelling: Towards prediction paradise? 2003 586 82 48%
Lipophilicity in drug discovery 2010 154 56 46%
Molecular obesity, potency and other addictions in drug discovery 2011 103 23 52%
Generation of a set of simple, interpretable ADMET rules of thumb 2008 289 92 35%
Considering the impact drug-like properties have on the chance of success 2013 12 12 75%
Improving Drug Candidates by Design: A Focus on Physicochemical Properties As a Means of Improving Compound Disposition and Safety 2011 101 89 40%
Getting physical in drug discovery: a contemporary perspective on solubility and hydrophobicity 2010 46 18 89%
The impact of aromatic ring count on compound developability: further insights by examining carbo- and hetero-aromatic and -aliphatic ring types 2011 77 16 50%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 CSC MED CHEM 6 80% 0.3% 4
2 SYST DRUG DESIGN 6 80% 0.3% 4
3 MODERNIZAT TRADIT CHINESE MED 3 20% 0.9% 13
4 CHEMPHARM DEV 3 50% 0.3% 4
5 AREA PHARM PHARMACEUT TECHNOL 3 60% 0.2% 3
6 MOL GR H DRUG DESIGN 3 60% 0.2% 3
7 PHARMACOCINET METAB 3 60% 0.2% 3
8 STAT INTELLIGENT DATA ANAL GRP 3 35% 0.4% 6
9 LEAD GENERAT DMPK PHYS CHEM 2 67% 0.1% 2
10 TRANSLAT PKPD GRP 2 67% 0.1% 2

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000189945 B IT//LIFE SCI INFORMAT//LIMES PROGRAM UNIT CHEM BIOL MED CHEM
2 0.0000176069 CACO 2//SINGLE PASS INTESTINAL PERFUSION//INTESTINAL PERFUSION
3 0.0000126046 BIOPARTITIONING MICELLAR CHROMATOGRAPHY//IMMOBILIZED LIPOSOME CHROMATOGRAPHY//MEMBRANE STRESS BIOTECHNOLOGY
4 0.0000124298 INTERSPECIES SCALING//DMPK TRANSLAT SCI//WELL STIRRED MODEL
5 0.0000118597 LIPOPHILICITY//RP TLC//RP HPTLC
6 0.0000094711 MOLECULAR SOLUTE DESCRIPTORS//SOLVATION PARAMETER MODEL//ALCOHOL SOLVENTS
7 0.0000090372 DISSOLUTION TECHNOLOGIES//BIORELEVANT MEDIA//BIOWAIVER
8 0.0000084682 NMR SCREENING//FRAGMENT BASED DRUG DISCOVERY//WATERLOGSY
9 0.0000081571 CLINICAL TRIAL RISK//CONTINUOUS IMPROVEMENT//STRATEGIE IND
10 0.0000079999 CP MLR//HAM 3//COMBINATORIAL PROTOCOL IN MULTIPLE LINEAR REGRESSION