Class information for:
Level 1: DNA GYRASE//GYRASE//REVERSE GYRASE

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
5748 1514 40.3 76%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
540 13989 FLUOROQUINOLONES//CIPROFLOXACIN//QUINOLONES

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 DNA GYRASE Author keyword 55 41% 7% 104
2 GYRASE Author keyword 32 49% 3% 47
3 REVERSE GYRASE Author keyword 30 84% 1% 16
4 CLOROBIOCIN Author keyword 15 82% 1% 9
5 SUPERCOILING Author keyword 11 24% 3% 40
6 DNA TOPOLOGY Author keyword 11 20% 3% 47
7 NOVIOSE Author keyword 11 78% 0% 7
8 POSITIVE SUPERCOILING Author keyword 11 78% 0% 7
9 DNA SUPERCOILING Author keyword 9 21% 3% 38
10 AMINOCOUMARIN ANTIBIOTICS Author keyword 9 83% 0% 5

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 DNA GYRASE 55 41% 7% 104 Search DNA+GYRASE Search DNA+GYRASE
2 GYRASE 32 49% 3% 47 Search GYRASE Search GYRASE
3 REVERSE GYRASE 30 84% 1% 16 Search REVERSE+GYRASE Search REVERSE+GYRASE
4 CLOROBIOCIN 15 82% 1% 9 Search CLOROBIOCIN Search CLOROBIOCIN
5 SUPERCOILING 11 24% 3% 40 Search SUPERCOILING Search SUPERCOILING
6 DNA TOPOLOGY 11 20% 3% 47 Search DNA+TOPOLOGY Search DNA+TOPOLOGY
7 NOVIOSE 11 78% 0% 7 Search NOVIOSE Search NOVIOSE
8 POSITIVE SUPERCOILING 11 78% 0% 7 Search POSITIVE+SUPERCOILING Search POSITIVE+SUPERCOILING
9 DNA SUPERCOILING 9 21% 3% 38 Search DNA+SUPERCOILING Search DNA+SUPERCOILING
10 AMINOCOUMARIN ANTIBIOTICS 9 83% 0% 5 Search AMINOCOUMARIN+ANTIBIOTICS Search AMINOCOUMARIN+ANTIBIOTICS

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 GYRASE GENES 48 65% 3% 46
2 N TERMINAL FRAGMENT 45 36% 7% 100
3 2 GATE MECHANISM 44 66% 3% 41
4 B PROTEIN 44 42% 5% 82
5 STRAND PASSAGE 44 72% 2% 34
6 COUMERMYCIN A1 41 81% 2% 25
7 LEU 500 PROMOTER 41 81% 2% 25
8 GYRASE 40 27% 8% 124
9 NOVOBIOCIN 36 33% 6% 90
10 IIA TOPOISOMERASES 36 71% 2% 29

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Non-quinolone Inhibitors of Bacterial Type IIA Topoisomerases: A Feat of Bioisosterism 2014 21 278 54%
DNA topoisomerases: harnessing and constraining energy to govern chromosome topology 2008 166 274 49%
Exploiting bacterial DNA gyrase as a drug target: current state and perspectives 2011 61 151 61%
Quinolone-mediated bacterial death 2008 146 72 51%
All tangled up: how cells direct, manage and exploit topoisomerase function 2011 98 199 34%
Prospects for Developing New Antibacterials Targeting Bacterial Type IIA Topoisomerases 2014 7 135 61%
Structure, molecular mechanisms, and evolutionary relationships in DNA topoisomerases 2004 246 155 47%
DNA gyrase, topoisomerase IV, and the 4-quinolones 1997 693 174 39%
Thirty years of Escherichia coli DNA gyrase: From in vivo function to single-molecule mechanism 2007 58 95 85%
Growth inhibition mediated by excess negative supercoiling: the interplay between transcription elongation, R-loop formation and DNA topology 2006 79 64 56%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 ENZYMOL ACIDES NUCL 7 64% 0.5% 7
2 PHARMAZEUT BIOL PHARMAZEUT 3 100% 0.2% 3
3 INFECT DIS CEDD 2 38% 0.3% 5
4 SCI PL COMP 2 67% 0.1% 2
5 INFECT INNOVAT MED UNIT 2 17% 0.7% 11
6 INFECT IMED 2 29% 0.4% 6
7 MOL METAB SIGNALLING 2 26% 0.4% 6
8 DIS DEV WORLD CEDD 1 100% 0.1% 2
9 FRE 2445EQUIPE MICROBIOL 1 100% 0.1% 2
10 GENET MICROBIOL ENZYMOL ACIDES NUCL 1 100% 0.1% 2

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000200716 TOPOISOMERASE II//ICRF 193//DNA TOPOISOMERASE II
2 0.0000114222 QNR//QEPA//AAC6 IB CR
3 0.0000100358 GEMIFLOXACIN//GEMIFLOXACIN MESYLATE//GARENOXACIN
4 0.0000096950 DIHYDROPYRAZOLE//OXIME ESTER//ULCEROGENIC EFFECT
5 0.0000093600 H NS//HISTONE LIKE PROTEIN//BACTERIAL CHROMATIN
6 0.0000084444 N SUBSTITUTED PIPERAZINYL QUINOLONES//PIPERAZINYL QUINOLONES//S ENOKI 3394
7 0.0000072153 EPIDEMIOLOGICAL SIGNIFICANCE//SIMILARITY IDENTIFICATION//AIRBORNE ESCHERICHIA COLI
8 0.0000068832 PARB//DNA SEGREGATION//FTSK
9 0.0000065542 ROPELENGTH//MOBIUS ENERGY//KNOT ENERGY
10 0.0000064351 C 14 PRECURSORS//CHEM TECHNOL TECH MICROBIOL BIOCHEM//AMMONIUM SALTS QUATERNARY