Class information for: |
Basic class information |
ID | Publications | Average number of references |
Avg. shr. active ref. in WoS |
---|---|---|---|
4782 | 1654 | 40.7 | 86% |
Classes in level above (level 2) |
Terms with highest relevance score |
Rank | Term | Type of term | Relevance score (tfidf) |
Class's shr. of term's tot. occurrences |
Shr. of publ. in class containing term |
Num. of publ. in class |
---|---|---|---|---|---|---|
1 | NS5B POLYMERASE | Author keyword | 140 | 87% | 4% | 68 |
2 | HCV NS5B POLYMERASE | Author keyword | 77 | 96% | 1% | 24 |
3 | NS3 PROTEASE | Author keyword | 55 | 70% | 3% | 46 |
4 | NS5B | Author keyword | 54 | 53% | 4% | 71 |
5 | HCVNS5B POLYMERASE | Author keyword | 26 | 100% | 1% | 11 |
6 | NS3 | Author keyword | 19 | 32% | 3% | 49 |
7 | HCV NS5B POLYMERASE INHIBITORS | Author keyword | 18 | 89% | 0% | 8 |
8 | NS3 4A PROTEASE | Author keyword | 17 | 68% | 1% | 15 |
9 | NS3 HELICASE | Author keyword | 16 | 58% | 1% | 19 |
10 | ANTIVIRAL THER Y | Address | 15 | 54% | 1% | 19 |
Web of Science journal categories |
Author Key Words |
Rank | Web of Science journal category | Relevance score (tfidf) |
Class's shr. of term's tot. occurrences |
Shr. of publ. in class containing term |
Num. of publ. in class |
LCSH search | Wikipedia search |
---|---|---|---|---|---|---|---|
1 | NS5B POLYMERASE | 140 | 87% | 4% | 68 | Search NS5B+POLYMERASE | Search NS5B+POLYMERASE |
2 | HCV NS5B POLYMERASE | 77 | 96% | 1% | 24 | Search HCV+NS5B+POLYMERASE | Search HCV+NS5B+POLYMERASE |
3 | NS3 PROTEASE | 55 | 70% | 3% | 46 | Search NS3+PROTEASE | Search NS3+PROTEASE |
4 | NS5B | 54 | 53% | 4% | 71 | Search NS5B | Search NS5B |
5 | HCVNS5B POLYMERASE | 26 | 100% | 1% | 11 | Search HCVNS5B+POLYMERASE | Search HCVNS5B+POLYMERASE |
6 | NS3 | 19 | 32% | 3% | 49 | Search NS3 | Search NS3 |
7 | HCV NS5B POLYMERASE INHIBITORS | 18 | 89% | 0% | 8 | Search HCV+NS5B+POLYMERASE+INHIBITORS | Search HCV+NS5B+POLYMERASE+INHIBITORS |
8 | NS3 4A PROTEASE | 17 | 68% | 1% | 15 | Search NS3+4A+PROTEASE | Search NS3+4A+PROTEASE |
9 | NS3 HELICASE | 16 | 58% | 1% | 19 | Search NS3+HELICASE | Search NS3+HELICASE |
10 | HCV POLYMERASE INHIBITORS | 15 | 88% | 0% | 7 | Search HCV+POLYMERASE+INHIBITORS | Search HCV+POLYMERASE+INHIBITORS |
Key Words Plus |
Rank | Web of Science journal category | Relevance score (tfidf) |
Class's shr. of term's tot. occurrences |
Shr. of publ. in class containing term |
Num. of publ. in class |
---|---|---|---|---|---|
1 | HCVNS5B POLYMERASE | 268 | 87% | 8% | 132 |
2 | NS4A COFACTOR PEPTIDE | 116 | 92% | 3% | 46 |
3 | NS5B POLYMERASE | 110 | 70% | 6% | 91 |
4 | DEPENDENT RNA POLYMERASE | 96 | 23% | 22% | 371 |
5 | NS4A | 71 | 72% | 3% | 55 |
6 | NS5B PROTEIN | 65 | 90% | 2% | 28 |
7 | FULL LENGTH NS3 | 61 | 95% | 1% | 20 |
8 | DE NOVO INITIATION | 59 | 49% | 5% | 87 |
9 | PEPTIDE BASED INHIBITORS | 56 | 76% | 2% | 39 |
10 | ALLOSTERIC INHIBITORS | 56 | 59% | 4% | 63 |
Journals |
Reviews |
Title | Publ. year | Cit. | Active references | % act. ref. to same field |
---|---|---|---|---|
Structure-Activity Relationships in the Development of Allosteric Hepatitis C Virus RNA-Dependent RNA Polymerase Inhibitors: Ten Years of Research | 2013 | 12 | 115 | 97% |
Challenges and successes in developing new therapies for hepatitis C | 2005 | 296 | 58 | 59% |
Hepatitis C Virus-Specific Directly Acting Antiviral Drugs | 2013 | 18 | 140 | 49% |
Recent advances in the development of NS5B polymerase inhibitors for the treatment of hepatitis C virus infection | 2009 | 67 | 48 | 81% |
Advances in the development of new therapeutic agents targeting the NS34A serine protease or the NS5B RNA-dependent RNA polymerase of the hepatitis C virus | 2007 | 84 | 115 | 86% |
Non-nucleoside inhibitors of the HCVNS5B polymerase: Progress in the discovery and development of novel agents for the treatment of HCV infections | 2007 | 80 | 74 | 84% |
Recent progress in the development of inhibitors of the hepatitis c virus RNA-Dependent RNA polymerase | 2007 | 76 | 127 | 78% |
Recent progress in the development of selected hepatitis C virus NS3.4A protease and NS5B polymerase inhibitors | 2008 | 87 | 44 | 70% |
HCV NS5B polymerase inhibitors | 2010 | 32 | 82 | 85% |
Chutes and ladders in hepatitis C nucleoside drug development | 2014 | 8 | 83 | 48% |
Address terms |
Rank | Address term | Relevance score (tfidf) |
Class's shr. of term's tot. occurrences |
Shr. of publ. in class containing term |
Num. of publ. in class |
---|---|---|---|---|---|
1 | ANTIVIRAL THER Y | 15 | 54% | 1.1% | 19 |
2 | MRL ROME | 7 | 64% | 0.4% | 7 |
3 | METAB VIRAL DIS EXCELLENCE DRUG DISCOVERY | 7 | 43% | 0.7% | 12 |
4 | IST RIC BIOL MOL P ANGELETTI SPA | 6 | 100% | 0.2% | 4 |
5 | MED CHEM ORGAN PHARMACEUT CHEM | 5 | 55% | 0.4% | 6 |
6 | IRBM | 5 | 30% | 0.8% | 13 |
7 | METAB ANTIVIRAL DIS EXCELLENCE DRUG DISCOVE | 3 | 100% | 0.2% | 3 |
8 | R4CQ | 3 | 100% | 0.2% | 3 |
9 | BIOCHEM INTERDISCIPLINARY PROGRAM | 2 | 67% | 0.1% | 2 |
10 | CHEM SCREENING SCI INFECT DIS | 2 | 50% | 0.2% | 3 |
Related classes at same level (level 1) |
Rank | Relatedness score | Related classes |
---|---|---|
1 | 0.0000196739 | STUDY HEPATITIS C//U748//VIROL INFECT DIS |
2 | 0.0000137278 | TELAPREVIR//RIBAVIRIN//BOCEPREVIR |
3 | 0.0000070730 | HCV GENOTYPES//INTERFERON SENSITIVITY DETERMINING REGION//HYPERVARIABLE REGION 1 |
4 | 0.0000062965 | WOMEN ARTS SCI EDUC//D GAUSS//ACETATE GROUP |
5 | 0.0000058005 | OBSTET GYNECOLSEALY STRUCT BIOL//PRIMASE//HELICASE |
6 | 0.0000053028 | PRONUCLEOTIDES//PROTIDE//PRONUCLEOTIDE |
7 | 0.0000051137 | RNA HELICASE//DEAD BOX//DEAD BOX PROTEIN |
8 | 0.0000047531 | AUREOBASIDIUM SPP//BREAKTHROUGH FUNGAEMIA//METALS METALLOIDS |
9 | 0.0000047522 | 3C PROTEASE//PICORNAVIRUS//PROTEINASE 3C |
10 | 0.0000045174 | IRES//INTERNAL RIBOSOME ENTRY SITE IRES//INTERNAL RIBOSOME ENTRY SITE |