Class information for:
Level 1: HIGH CELL DENSITY CULTIVATION//RECOMBINANT ESCHERICHIA COLI//ACETATE EXCRETION

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
4542 1695 29.3 68%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
958 10272 BIOTECHNOLOGY AND BIOENGINEERING//MAMMALIAN CELL CULTURE//HYBRIDOMA

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 HIGH CELL DENSITY CULTIVATION Author keyword 20 46% 2% 32
2 RECOMBINANT ESCHERICHIA COLI Author keyword 15 28% 3% 47
3 ACETATE EXCRETION Author keyword 11 100% 0% 6
4 SWEDISH BIOPROC TECHNOL Address 11 100% 0% 6
5 PLASMID STABILITY Author keyword 10 20% 3% 47
6 TEMPERATURE INDUCTION Author keyword 7 57% 0% 8
7 AUTOMAT CONTROL TECHNOL Address 6 80% 0% 4
8 FED BATCH Author keyword 6 10% 3% 57
9 RECOMBINANT PROTEIN PRODUCTION Author keyword 6 15% 2% 36
10 RECOMBINANT FERMENTATION Author keyword 5 45% 1% 9

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 HIGH CELL DENSITY CULTIVATION 20 46% 2% 32 Search HIGH+CELL+DENSITY+CULTIVATION Search HIGH+CELL+DENSITY+CULTIVATION
2 RECOMBINANT ESCHERICHIA COLI 15 28% 3% 47 Search RECOMBINANT+ESCHERICHIA+COLI Search RECOMBINANT+ESCHERICHIA+COLI
3 ACETATE EXCRETION 11 100% 0% 6 Search ACETATE+EXCRETION Search ACETATE+EXCRETION
4 PLASMID STABILITY 10 20% 3% 47 Search PLASMID+STABILITY Search PLASMID+STABILITY
5 TEMPERATURE INDUCTION 7 57% 0% 8 Search TEMPERATURE+INDUCTION Search TEMPERATURE+INDUCTION
6 FED BATCH 6 10% 3% 57 Search FED+BATCH Search FED+BATCH
7 RECOMBINANT PROTEIN PRODUCTION 6 15% 2% 36 Search RECOMBINANT+PROTEIN+PRODUCTION Search RECOMBINANT+PROTEIN+PRODUCTION
8 RECOMBINANT FERMENTATION 5 45% 1% 9 Search RECOMBINANT+FERMENTATION Search RECOMBINANT+FERMENTATION
9 PLASMID INSTABILITY 4 39% 1% 9 Search PLASMID+INSTABILITY Search PLASMID+INSTABILITY
10 CLONED GENE EXPRESSION 4 67% 0% 4 Search CLONED+GENE+EXPRESSION Search CLONED+GENE+EXPRESSION

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 HIGH CELL DENSITY 50 43% 5% 89
2 ACETATE ACCUMULATION 29 63% 2% 29
3 FERMENTER CULTURES 24 91% 1% 10
4 ACETATE INHIBITION 23 100% 1% 10
5 FED BATCH CULTURES 15 26% 3% 52
6 CELL DENSITY CULTIVATION 15 31% 2% 41
7 SEGREGATED MODEL 15 88% 0% 7
8 DO STAT 12 63% 1% 12
9 CELL DENSITY CULTURES 11 60% 1% 12
10 ALPHA CONSENSUS INTERFERON 11 100% 0% 6

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Growing E-coli to high cell density - A historical perspective on method development 2005 152 46 85%
Overcoming acetate in Escherichia coli recombinant protein fermentations 2006 120 68 65%
Industrial production of recombinant therapeutics in Escherichia coli and its recent advancements 2012 63 121 30%
RECOMBINANT PROTEIN EXPRESSION IN HIGH CELL-DENSITY FED-BATCH CULTURES OF ESCHERICHIA-COLI 1992 158 39 82%
Production of recombinant proteins by high cell density culture of Escherichia coli 2006 114 61 46%
METABOLIC LOAD AND HETEROLOGOUS GENE-EXPRESSION 1995 230 48 50%
Secretory and extracellular production of recombinant proteins using Escherichia coli 2004 193 71 27%
High Yield Production of Heterologous Proteins with Escherichia coli 2009 20 60 63%
Recombinant protein production in bacterial hosts 2014 6 63 19%
Production of recombinant proteins in E. coli by the heat inducible expression system based on the phage lambda pL and/or pR promoters 2010 26 149 36%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ.
in class
1 SWEDISH BIOPROC TECHNOL 11 100% 0.4% 6
2 AUTOMAT CONTROL TECHNOL 6 80% 0.2% 4
3 UNITAT BIOCATALISI LICADA ASSOCIADA IQAC 4 75% 0.2% 3
4 ESCOLA TECN SUPER ENGN ENGN QUIM 3 100% 0.2% 3
5 BIOCHEM PROC ENGN RU 3 60% 0.2% 3
6 BIOL PROC SCI 2 67% 0.1% 2
7 SHAANXI SOURCE PLICAT CHEM ENGN 2 67% 0.1% 2
8 TECNOL RECOMBINANTE LATER 2 67% 0.1% 2
9 UNITAT BIOCATALISI LICADA ASSOCIADA IIQA 2 67% 0.1% 2
10 SHAANXI RD BIOMAT FERMENTAT ENGN 2 20% 0.5% 9

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000197037 UNITE BIOIND CWBI//SCALE DOWN//MICROBIAL STRESS
2 0.0000128006 TYRR//SHIKIMIC ACID PRODUCTION//CIS CIS MUCONIC ACID
3 0.0000123990 INFLOW NOISE//GEN CHEM BIOSYST//PHYSIOLOGICAL STATE RECOGNITION
4 0.0000111626 PROTEIN REFOLDING//INCLUSION BODIES//REFOLDING
5 0.0000101537 CYBERNETIC MODELING//SUBSTITUTABLE SUBSTRATES//CYBERNETIC MODELS
6 0.0000089479 ONLINE FERMENTATION MONITORING//ON LINE SAMPLING//FERMENTATION MONITORING
7 0.0000082347 2 MU M PLASMID//SUC2 PROMOTER//PLASMID STABILITY
8 0.0000076430 PLASMID PURIFICATION//SUPERCOILED PLASMID DNA//PLASMID DNA
9 0.0000075099 SHAKEN BIOREACTOR//SHAKE FLASK//BIOLECTOR
10 0.0000074538 SD SEQUENCE//RIBOSOMAL PROTEIN S1//SHINE DALGARNO SEQUENCE