Class information for:
Level 1: TIRAPAZAMINE//HYPOXIC CELL RADIOSENSITIZER//KU 2285

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
4351 1725 30.7 58%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
1439 7339 BNCT//BORON NEUTRON CAPTURE THERAPY//TIRAPAZAMINE

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 TIRAPAZAMINE Author keyword 97 68% 5% 86
2 HYPOXIC CELL RADIOSENSITIZER Author keyword 55 92% 1% 22
3 KU 2285 Author keyword 42 94% 1% 15
4 SR 2508 Author keyword 42 94% 1% 15
5 AQ4N Author keyword 38 89% 1% 17
6 BIOREDUCTIVE DRUGS Author keyword 37 57% 3% 44
7 PR 104 Author keyword 34 93% 1% 13
8 SR 4233 Author keyword 29 73% 1% 22
9 ETANIDAZOLE Author keyword 28 57% 2% 34
10 DORANIDAZOLE Author keyword 27 92% 1% 11

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 TIRAPAZAMINE 97 68% 5% 86 Search TIRAPAZAMINE Search TIRAPAZAMINE
2 HYPOXIC CELL RADIOSENSITIZER 55 92% 1% 22 Search HYPOXIC+CELL+RADIOSENSITIZER Search HYPOXIC+CELL+RADIOSENSITIZER
3 KU 2285 42 94% 1% 15 Search KU+2285 Search KU+2285
4 SR 2508 42 94% 1% 15 Search SR+2508 Search SR+2508
5 AQ4N 38 89% 1% 17 Search AQ4N Search AQ4N
6 BIOREDUCTIVE DRUGS 37 57% 3% 44 Search BIOREDUCTIVE+DRUGS Search BIOREDUCTIVE+DRUGS
7 PR 104 34 93% 1% 13 Search PR+104 Search PR+104
8 SR 4233 29 73% 1% 22 Search SR+4233 Search SR+4233
9 ETANIDAZOLE 28 57% 2% 34 Search ETANIDAZOLE Search ETANIDAZOLE
10 DORANIDAZOLE 27 92% 1% 11 Search DORANIDAZOLE Search DORANIDAZOLE

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 SR 4233 143 73% 6% 110
2 3 AMINO 1 2 4 BENZOTRIAZINE 1 4 DIOXIDE TIRAPAZAMINE 65 95% 1% 21
3 1 2 4 BENZOTRIAZINE 1 4 DIOXIDES 45 90% 1% 19
4 MISONIDAZOLE 39 30% 6% 109
5 BIOREDUCTIVE AGENT 38 78% 1% 25
6 RSU 1069 34 59% 2% 38
7 TIRAPAZAMINE 33 45% 3% 55
8 3 AMINO 1 2 4 BENZOTRIAZINE 1 4 DIOXIDE 30 79% 1% 19
9 HYPOXIC CELL RADIOSENSITIZERS 29 58% 2% 34
10 REDUCTIVE BIOACTIVATION 27 76% 1% 19

Journals


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 CANCER CLINICAL TRIALS 3 16% 1% 20

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Bioreductive prodrugs as cancer therapeutics: targeting tumor hypoxia 2014 11 69 59%
Exploiting tumour hypoxia in cancer treatment 2004 764 118 38%
Targeting hypoxia in cancer therapy 2011 391 166 25%
Design of Anticancer Prodrugs for Reductive Activation 2009 129 198 36%
The hypoxic cell: A target for selective cancer therapy - Eighteenth Bruce F. Cain Memorial Award lecture 1999 410 74 30%
SR-4233 (TIRAPAZAMINE) - A NEW ANTICANCER DRUG EXPLOITING HYPOXIA IN SOLID TUMORS 1993 236 52 63%
Bioreductive drugs: from concept to clinic 2007 91 155 46%
Hypoxia-activated prodrugs in cancer therapy: progress to the clinic 2010 28 56 66%
Exploiting the hypoxic cancer cell: mechanisms and therapeutic strategies 2000 221 24 42%
Hypoxia-specific cytotoxins in cancer therapy 1996 69 88 59%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 AUCKLAND CANC SOC 12 14% 4.6% 80
2 EXPT ONCOL GRP 2 22% 0.5% 8
3 AUCKLAND CANC SOCIETY 1 38% 0.2% 3
4 DCTDFAIRVIEW 1 100% 0.1% 2
5 ONCOL RADIAT ONCOLRADIOBIOL 1 100% 0.1% 2
6 PHYS 500 SHERBOURNE ST 1 27% 0.2% 3
7 CANC SOC 1 17% 0.3% 5
8 RADIAT SCI GRP 1 17% 0.2% 4
9 BREAST BIOL CANC UNIT 1 50% 0.1% 1
10 CALIF CANC CONSORTIUM 1 50% 0.1% 1

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000214596 QUIESCENT CELL//BORON TRACEDRUG//MILD TEMPERATURE HYPERTHERMIA
2 0.0000207657 KIMMELL CANC//MERCURY ORANGE//ANTI SINGLE STRANDED DNA ANTIBODY
3 0.0000203853 CARBOGEN//TUMOR HYPOXIA//TUMOR OXYGENATION
4 0.0000124585 MED MEANS CHEM//EMIZCO//P NITROACETOPHENONE
5 0.0000100945 NITRO RADICAL ANION//NIFURTIMOX//BIOELE OCHEM
6 0.0000085067 CB1954//ADEPT//ANTIBODY DIRECTED ENZYME PRODRUG THERAPY
7 0.0000065460 DT DIAPHORASE//EO9//NQO1
8 0.0000060492 FLUOSOL//PERFLUOROCHEMICAL EMULSION//BIOMATERIALS ARTIFICIAL CELLS AND ARTIFICIAL ORGANS
9 0.0000059278 LOW DOSE HYPER RADIOSENSITIVITY//HYPER RADIOSENSITIVITY//ULTRAFRACTIONATION
10 0.0000053678 FRACTIONATED X IRRADIATION//RAT YOLK SAC TUMOR//DRUG EFFECT ON BRAIN