Class information for:
Level 1: ATLA-ALTERNATIVES TO LABORATORY ANIMALS//EYE IRRITATION//DRAIZE TEST

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
4268 1741 27.5 53%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
1481 7128 ENDOPHTHALMITIS//ATLA-ALTERNATIVES TO LABORATORY ANIMALS//EYE IRRITATION

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 ATLA-ALTERNATIVES TO LABORATORY ANIMALS Journal 128 28% 22% 383
2 EYE IRRITATION Author keyword 88 62% 5% 92
3 DRAIZE TEST Author keyword 58 76% 2% 41
4 MEIC Author keyword 53 89% 1% 24
5 SKIN CORROSION Author keyword 44 88% 1% 21
6 TOXICOLOGY IN VITRO Journal 43 10% 23% 406
7 DRAIZE EYE IRRITATION TEST Author keyword 34 93% 1% 13
8 DRAIZE EYE TEST Author keyword 27 83% 1% 15
9 BCOP Author keyword 26 100% 1% 11
10 ECVAM Author keyword 26 53% 2% 34

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 EYE IRRITATION 88 62% 5% 92 Search EYE+IRRITATION Search EYE+IRRITATION
2 DRAIZE TEST 58 76% 2% 41 Search DRAIZE+TEST Search DRAIZE+TEST
3 MEIC 53 89% 1% 24 Search MEIC Search MEIC
4 SKIN CORROSION 44 88% 1% 21 Search SKIN+CORROSION Search SKIN+CORROSION
5 DRAIZE EYE IRRITATION TEST 34 93% 1% 13 Search DRAIZE+EYE+IRRITATION+TEST Search DRAIZE+EYE+IRRITATION+TEST
6 DRAIZE EYE TEST 27 83% 1% 15 Search DRAIZE+EYE+TEST Search DRAIZE+EYE+TEST
7 BCOP 26 100% 1% 11 Search BCOP Search BCOP
8 ECVAM 26 53% 2% 34 Search ECVAM Search ECVAM
9 ALTERNATIVE METHODS 24 29% 4% 71 Search ALTERNATIVE+METHODS Search ALTERNATIVE+METHODS
10 SKIN CORROSIVITY 23 100% 1% 10 Search SKIN+CORROSIVITY Search SKIN+CORROSIVITY

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 EYE IRRITATION TEST 71 74% 3% 53
2 BOVINE CORNEAL OPACITY 56 84% 2% 31
3 OCULAR IRRITANCY 56 75% 2% 41
4 SKIN CORROSIVITY 47 81% 2% 29
5 IN VITRO TESTS 42 59% 3% 47
6 ALTERNATIVES PROGRAM 42 94% 1% 15
7 CHORIOALLANTOIC MEMBRANE TEST 41 100% 1% 15
8 HET CAM TEST 38 76% 1% 26
9 POTENTIAL ALTERNATIVES 37 100% 1% 14
10 IRRITANCY 34 42% 4% 62

Journals


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 ATLA-ALTERNATIVES TO LABORATORY ANIMALS 128 28% 22% 383
2 TOXICOLOGY IN VITRO 43 10% 23% 406
3 JOURNAL OF TOXICOLOGY-CUTANEOUS AND OCULAR TOXICOLOGY 11 15% 4% 69
4 IN VITRO & MOLECULAR TOXICOLOGY-A JOURNAL OF BASIC AND APPLIED RESEARCH 1 11% 1% 11

Reviews


Title Publ. year Cit. Active
references		 % act. ref.
to same field
A proposed eye irritation testing strategy to reduce and replace in vivo studies using Bottom-Up and Top-Down approaches 2010 39 21 100%
The Draize eye test 2001 88 39 82%
An overview of current techniques for ocular toxicity testing 2015 1 81 67%
Alternative methods for eye and skin irritation tests: An overview 2008 49 80 88%
A prevalidation study on in vitro tests for acute skin irritation: results and evaluation by the Management Team 2001 66 22 82%
REPLACEMENT OF ANIMAL PROCEDURES - ALTERNATIVES IN RESEARCH, EDUCATION AND TESTING 1994 45 15 87%
The potential of tissue engineering for developing alternatives to animal experiments: a systematic review 2015 2 19 21%
Cross-Sector Review of Drivers and Available 3Rs Approaches for Acute Systemic Toxicity Testing 2010 11 12 75%
Refinement and Reduction of Acute Oral Toxicity Testing: A Critical Review of the Use of Cytotoxicity Data 2011 9 16 63%
Scandinavian Society for Cell Toxicology - Thirty Years of Scientific Pioneering 2014 1 15 93%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 FRAME ALTERNAT 18 67% 0.9% 16
2 ECVAM 10 21% 2.4% 41
3 BIOCHEM TOXIKOL 8 75% 0.3% 6
4 GENET MUTAGEN 8 100% 0.3% 5
5 BGVV 7 43% 0.7% 13
6 REFERENCE COSMET 6 80% 0.2% 4
7 HUMAN SAFETY EVALUAT 6 71% 0.3% 5
8 RUSSELL BURCH HOUSE 5 55% 0.3% 6
9 ASSESSMENT CHEM 4 47% 0.4% 7
10 HUMAN ENVIRONM SAFETY EVALUAT 4 67% 0.2% 4

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000115153 SENSITIVE SKIN//BIOENGINEERING METHODS//CORNEOSURFAMETRY
2 0.0000109514 COMPUTAT TOXICOL//ALTERNAT ANIM TESTING//ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION
3 0.0000100055 FISH CELL LINES//FISH CELL LINE//PASSIVE DOSING
4 0.0000090373 BIOL PHARMACOL SCI//BENZALKONIUM CHLORIDE//SOFZIA
5 0.0000080911 POLLEN PEPTIDE//L 4 OXALYSINE//ALPHA ANORDRIN
6 0.0000059216 THREE RS//SYRCLE//DIRECTIVE 86 609 EEC
7 0.0000055638 CFU GM ASSAY//ACUTE NEUTROPENIA//PYRAZINE DIAZOHYDROXIDE
8 0.0000049154 SKIN SENSITIZATION//LOCAL LYMPH NODE ASSAY//LLNA
9 0.0000048623 EMBRYONIC STEM CELL TEST//HLTH RISK ANAL TOXICOL GRAT//ALTERNATIVE TEST METHOD
10 0.0000047048 RDS TEST//NONGENOTOXIC HEPATOCARCINOGENS//HEPA 1