Class information for:
Level 1: FREEZE DRYING//LYOPHILIZATION//FREEZE DRYING LYOPHILIZATION

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
4133 1766 33.0 62%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
1386 7667 SPRAY DRYING//FREEZE DRYING//LYOPHILIZATION

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 FREEZE DRYING Author keyword 91 21% 22% 391
2 LYOPHILIZATION Author keyword 70 28% 12% 211
3 FREEZE DRYING LYOPHILIZATION Author keyword 29 71% 1% 24
4 PRIMARY DRYING Author keyword 29 88% 1% 14
5 LYOPHILIZED FORMULATION Author keyword 21 85% 1% 11
6 SECONDARY DRYING Author keyword 18 89% 0% 8
7 FREEZE DRYING FOCUS GRP Address 13 62% 1% 13
8 AMORPHOUS SUGAR Author keyword 12 63% 1% 12
9 MANOMETRIC TEMPERATURE MEASUREMENT Author keyword 12 86% 0% 6
10 FREEZE DRYING OF PHARMACEUTICALS Author keyword 11 100% 0% 6

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 FREEZE DRYING 91 21% 22% 391 Search FREEZE+DRYING Search FREEZE+DRYING
2 LYOPHILIZATION 70 28% 12% 211 Search LYOPHILIZATION Search LYOPHILIZATION
3 FREEZE DRYING LYOPHILIZATION 29 71% 1% 24 Search FREEZE+DRYING+LYOPHILIZATION Search FREEZE+DRYING+LYOPHILIZATION
4 PRIMARY DRYING 29 88% 1% 14 Search PRIMARY+DRYING Search PRIMARY+DRYING
5 LYOPHILIZED FORMULATION 21 85% 1% 11 Search LYOPHILIZED+FORMULATION Search LYOPHILIZED+FORMULATION
6 SECONDARY DRYING 18 89% 0% 8 Search SECONDARY+DRYING Search SECONDARY+DRYING
7 AMORPHOUS SUGAR 12 63% 1% 12 Search AMORPHOUS+SUGAR Search AMORPHOUS+SUGAR
8 MANOMETRIC TEMPERATURE MEASUREMENT 12 86% 0% 6 Search MANOMETRIC+TEMPERATURE+MEASUREMENT Search MANOMETRIC+TEMPERATURE+MEASUREMENT
9 FREEZE DRYING OF PHARMACEUTICALS 11 100% 0% 6 Search FREEZE+DRYING+OF+PHARMACEUTICALS Search FREEZE+DRYING+OF+PHARMACEUTICALS
10 COLLAPSE TEMPERATURE 10 73% 0% 8 Search COLLAPSE+TEMPERATURE Search COLLAPSE+TEMPERATURE

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 MANOMETRIC TEMPERATURE MEASUREMENT 138 96% 2% 44
2 LYOPHILIZATION 130 56% 9% 160
3 PRODUCT TEMPERATURE 77 96% 1% 24
4 PRACTICAL ADVICE 49 79% 2% 31
5 STRESS SPECIFIC STABILIZATION 49 69% 2% 42
6 AMORPHOUS SOLUTES 34 93% 1% 13
7 DRYING INDUCED DENATURATION 34 65% 2% 32
8 PROTEIN FORMULATIONS 32 63% 2% 32
9 MICROBALANCE TECHNIQUE 27 92% 1% 11
10 PHARMACEUTICAL CRYSTALLINE 26 100% 1% 11

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Design of freeze-drying processes for pharmaceuticals: Practical advice 2004 226 25 84%
The freezing step in lyophilization: Physico-chemical fundamentals, freezing methods and consequences on process performance and quality attributes of biopharmaceuticals 2011 58 88 69%
Lyophilization and development of solid protein pharmaceuticals 2000 435 212 64%
Mechanisms of Protein Stabilization in the Solid State 2009 65 110 58%
Rational design of stable lyophilized protein formulations: Some practical advice 1997 308 25 80%
The role of vitrification in anhydrobiosis 1998 672 55 40%
Protein stability during freezing: Separation of stresses and mechanisms of protein stabilization 2007 80 102 69%
Trehalose: Current Use and Future Applications 2011 68 203 31%
Correlations between molecular mobility and chemical stability during storage of amorphous pharmaceuticals 2007 65 108 68%
Physical characterization of pharmaceutical formulations in frozen and freeze-dried solid states: Techniques and applications in freeze-drying development 2006 50 128 75%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 FREEZE DRYING FOCUS GRP 13 62% 0.7% 13
2 BIOPHARMA SOLUT 11 78% 0.4% 7
3 PARENTERAL EMPHASIS 5 60% 0.3% 6
4 UMR Q 5007 4 75% 0.2% 3
5 IST INGN CHIM 4 56% 0.3% 5
6 PHARM PHARMACEUT TECHNOL BIOPHARMACEUT 3 14% 1.0% 17
7 BIOCHEM PROC 2 23% 0.5% 9
8 CIENCIAS EXACTAS NAT IND 2 44% 0.2% 4
9 BIOPHARMACEUT DEV RD 2 67% 0.1% 2
10 CRYOMED FOOD FREEZING 2 67% 0.1% 2

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000147812 ANHYDROBIOLOGY//METHYLPHOSPHOCHOLINE//FISICOQUIM MEMBRANAS LIPID LIPOSOMAS
2 0.0000129753 PROTEIN FORMULATION//SUBVISIBLE PARTICLES//PROTEIN AGGREGATION
3 0.0000117288 SPRAY DRYING//SINGLE DROPLET DRYING//DRYING PROC TECHNOL GRP
4 0.0000087759 ICE CREAM//FROZEN DESSERT//FAT DESTABILIZATION
5 0.0000087247 DUCHENNE MYODYSTROPHY//GENE TRANSFER AND DELIVERY//GENETIC PASSPORT
6 0.0000075695 UNITA RIC ROMA TRE//DYNAMICAL TRANSITION//UFR PHITEM
7 0.0000072671 AMORPHOUS CONTENT//ISOTHERMAL MICROCALORIMETRY//SORPTION CALORIMETRY
8 0.0000068206 CRYOBIOLOGY//INTRACELLULAR ICE FORMATION//CRYO-LETTERS
9 0.0000067912 JIANGSU PROV PHOTOELECT TECHNOL//BIOL ENGN BIOMED ENGN//DIPYRIMIDINE
10 0.0000065080 ESCHERICHIA COLI ALKALINE PHOSPHATASE//ROOM TEMPERATURE TRYPTOPHAN PHOSPHORESCENCE//TRYPTOPHAN PHOSPHORESCENCE