Class information for:
Level 1: RNA INTERFERENCE//SIRNA//RNAI

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
400 3455 49.1 93%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
1483 7123 PIRNA//RNA INTERFERENCE//PIWI

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 RNA INTERFERENCE Author keyword 122 16% 20% 687
2 SIRNA Author keyword 110 16% 19% 651
3 RNAI Author keyword 82 16% 14% 478
4 SIRNA DESIGN Author keyword 48 100% 0% 17
5 SHRNA Author keyword 43 22% 5% 170
6 SMALL INTERFERING RNAS Author keyword 41 20% 5% 186
7 GENE SILENCING Author keyword 26 13% 6% 192
8 U6 PROMOTER Author keyword 25 66% 1% 23
9 SHORT HAIRPIN RNAS Author keyword 17 24% 2% 63
10 ANTIVIRAL GENE THER Y UNIT Address 17 50% 1% 24

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 RNA INTERFERENCE 122 16% 20% 687 Search RNA+INTERFERENCE Search RNA+INTERFERENCE
2 SIRNA 110 16% 19% 651 Search SIRNA Search SIRNA
3 RNAI 82 16% 14% 478 Search RNAI Search RNAI
4 SIRNA DESIGN 48 100% 0% 17 Search SIRNA+DESIGN Search SIRNA+DESIGN
5 SHRNA 43 22% 5% 170 Search SHRNA Search SHRNA
6 SMALL INTERFERING RNAS 41 20% 5% 186 Search SMALL+INTERFERING+RNAS Search SMALL+INTERFERING+RNAS
7 GENE SILENCING 26 13% 6% 192 Search GENE+SILENCING Search GENE+SILENCING
8 U6 PROMOTER 25 66% 1% 23 Search U6+PROMOTER Search U6+PROMOTER
9 SHORT HAIRPIN RNAS 17 24% 2% 63 Search SHORT+HAIRPIN+RNAS Search SHORT+HAIRPIN+RNAS
10 RNA INTERFERENCE RNAI 16 22% 2% 62 Search RNA+INTERFERENCE+RNAI Search RNA+INTERFERENCE+RNAI

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 SMALL INTERFERING RNAS 316 32% 24% 821
2 SHORT HAIRPIN RNAS 245 63% 7% 250
3 FUNCTIONAL SIRNAS 149 98% 1% 40
4 DOUBLE STRANDED RNA 99 10% 27% 935
5 SIRNAS 86 33% 6% 213
6 SIRNA 84 23% 9% 323
7 IN VIVO DELIVERY 75 45% 4% 127
8 HAIRPIN RNAS 72 54% 3% 94
9 SHORT INTERFERING RNAS 64 36% 4% 146
10 STABLE SUPPRESSION 61 82% 1% 36

Journals


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 OLIGONUCLEOTIDES 8 17% 1% 45
2 NUCLEIC ACID THERAPEUTICS 3 13% 1% 25
3 MOLECULAR THERAPY-NUCLEIC ACIDS 3 11% 1% 24

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
The promises and pitfalls of RNA-interference-based therapeutics 2009 548 93 57%
Preclinical and clinical development of siRNA-based therapeutics 2015 5 110 53%
Interfering with disease: a progress report on siRNA-based therapeutics 2007 586 100 72%
Current prospects for RNA interference-based therapies 2011 260 161 50%
RNA-Based Therapeutics: Current Progress and Future Prospects 2012 216 68 44%
Strategies for silencing human disease using RNA interference 2007 515 86 67%
Molecular Mechanisms of RNA Interference 2013 100 96 42%
RNAi therapeutics: a potential new class of pharmaceutical drugs 2006 462 75 80%
RNA interference in the clinic: challenges and future directions 2011 220 93 41%
Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application 2010 246 110 63%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 ANTIVIRAL GENE THER Y UNIT 17 50% 0.7% 24
2 SKIP ACKERMAN MOL THER EUT 10 73% 0.2% 8
3 GLOBAL RNAI MED 6 37% 0.4% 13
4 DROSOPHILA RNAI SCREENING 6 47% 0.3% 9
5 GLOBAL PHARMACEUT ANALYT SCI 4 67% 0.1% 4
6 CINIMA MED 4 75% 0.1% 3
7 RNA THER EUT 3 19% 0.4% 14
8 HEPATITIS B VIRUS UNIT 3 60% 0.1% 3
9 SECT INFECT DIS IMMUNOBIOL 3 60% 0.1% 3
10 VIRUS ENTEROTROPES STRATEGIES ANTIVIRALES 3 60% 0.1% 3

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000166716 SMALL ACTIVATING RNA//SARNA//RNA ACTIVATION
2 0.0000129046 SYSTEMIC RNAI//K STATE ARTHROPOD GENOM//DSRNA FEEDING
3 0.0000089427 PIRNA//PIWI//PIRNAS
4 0.0000087447 GW182//DROSHA//ARGONAUTE
5 0.0000073821 RNA SILENCING//POST TRANSCRIPTIONAL GENE SILENCING//VIRUS INDUCED GENE SILENCING
6 0.0000073510 O I//VIRAL MICRORNAS//VIRAL MIRNA
7 0.0000063808 GENE DELIVERY//POLYETHYLENIMINE//POLYPLEX
8 0.0000055916 REVERSE TRANSFECTION//SUBSTRATE MEDIATED DELIVERY//SUBSTRATE MEDIATED
9 0.0000047805 EXON SKIPPING//DMD GENET THER Y GRP//MC LOCKWOOD MUSCULAR DYSTROPHY
10 0.0000040885 HYDRODYNAMICS BASED PROCEDURE//HYDRODYNAMICS BASED TRANSFECTION//HYDRODYNAMIC DELIVERY