Class information for:
Level 1: LIPOYL DOMAIN//PYRUVATE DEHYDROGENASE COMPLEX//DIHYDROLIPOAMIDE DEHYDROGENASE

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
3797 1830 33.8 64%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
2279 4195 LIPOYL DOMAIN//PYRUVATE DEHYDROGENASE COMPLEX//NONKETOTIC HYPERGLYCINEMIA

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 LIPOYL DOMAIN Author keyword 94 97% 2% 28
2 PYRUVATE DEHYDROGENASE COMPLEX Author keyword 85 47% 7% 133
3 DIHYDROLIPOAMIDE DEHYDROGENASE Author keyword 59 64% 3% 58
4 PYRUVATE DEHYDROGENASE KINASE Author keyword 40 54% 3% 52
5 PYRIDINE NUCLEOTIDE DISULFIDE OXIDOREDUCTASE Author keyword 33 100% 1% 13
6 PYRUVATE DEHYDROGENASE Author keyword 30 24% 6% 111
7 PYRUVATE DEHYDROGENASE COMPLEX DEFICIENCY Author keyword 28 81% 1% 17
8 PYRUVATE DEHYDROGENASE DEFICIENCY Author keyword 28 69% 1% 24
9 PYRUVATE DEHYDROGENASE PHOSPHATASE Author keyword 15 71% 1% 12
10 DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE Author keyword 15 88% 0% 7

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 LIPOYL DOMAIN 94 97% 2% 28 Search LIPOYL+DOMAIN Search LIPOYL+DOMAIN
2 PYRUVATE DEHYDROGENASE COMPLEX 85 47% 7% 133 Search PYRUVATE+DEHYDROGENASE+COMPLEX Search PYRUVATE+DEHYDROGENASE+COMPLEX
3 DIHYDROLIPOAMIDE DEHYDROGENASE 59 64% 3% 58 Search DIHYDROLIPOAMIDE+DEHYDROGENASE Search DIHYDROLIPOAMIDE+DEHYDROGENASE
4 PYRUVATE DEHYDROGENASE KINASE 40 54% 3% 52 Search PYRUVATE+DEHYDROGENASE+KINASE Search PYRUVATE+DEHYDROGENASE+KINASE
5 PYRIDINE NUCLEOTIDE DISULFIDE OXIDOREDUCTASE 33 100% 1% 13 Search PYRIDINE+NUCLEOTIDE+DISULFIDE+OXIDOREDUCTASE Search PYRIDINE+NUCLEOTIDE+DISULFIDE+OXIDOREDUCTASE
6 PYRUVATE DEHYDROGENASE 30 24% 6% 111 Search PYRUVATE+DEHYDROGENASE Search PYRUVATE+DEHYDROGENASE
7 PYRUVATE DEHYDROGENASE COMPLEX DEFICIENCY 28 81% 1% 17 Search PYRUVATE+DEHYDROGENASE+COMPLEX+DEFICIENCY Search PYRUVATE+DEHYDROGENASE+COMPLEX+DEFICIENCY
8 PYRUVATE DEHYDROGENASE DEFICIENCY 28 69% 1% 24 Search PYRUVATE+DEHYDROGENASE+DEFICIENCY Search PYRUVATE+DEHYDROGENASE+DEFICIENCY
9 PYRUVATE DEHYDROGENASE PHOSPHATASE 15 71% 1% 12 Search PYRUVATE+DEHYDROGENASE+PHOSPHATASE Search PYRUVATE+DEHYDROGENASE+PHOSPHATASE
10 DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE 15 88% 0% 7 Search DIHYDROLIPOAMIDE+SUCCINYLTRANSFERASE Search DIHYDROLIPOAMIDE+SUCCINYLTRANSFERASE

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 TRANSACETYLASE COMPONENT 89 100% 1% 27
2 MULTIENZYME COMPLEX 88 42% 9% 161
3 E1 ALPHA SUBUNIT 69 66% 4% 65
4 DIHYDROLIPOYL ACETYLTRANSFERASE COMPONENT 69 96% 1% 22
5 COMPLEX DEFICIENCY 66 83% 2% 38
6 LIPOAMIDE DEHYDROGENASE 57 34% 7% 136
7 DIHYDROLIPOYL ACETYLTRANSFERASE 56 89% 1% 25
8 LIPOYL DOMAIN 54 68% 3% 48
9 DIHYDROLIPOYL TRANSACETYLASE COMPONENT 50 88% 1% 23
10 PROTEIN X 47 66% 2% 43

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Swinging arms and swinging domains in multifunctional enzymes: Catalytic machines for multistep reactions 2000 275 232 49%
Recent advances in mechanisms regulating glucose oxidation at the level of the pyruvate dehydrogenase complex by PDKs 2003 167 67 73%
The Pyruvate Dehydrogenase Complexes: Structure-based Function and Regulation 2014 9 90 66%
Pyruvate dehydrogenase kinase regulatory mechanisms and inhibition in treating diabetes, heart ischemia, and cancer 2007 97 150 57%
The spectrum of pyruvate dehydrogenase complex deficiency: Clinical, biochemical and genetic features in 371 patients 2012 11 155 86%
Regulation of the activity of the pyruvate dehydrogenase complex 2002 108 40 83%
STRUCTURE-FUNCTION-RELATIONSHIPS IN DIHYDROLIPOAMIDE ACYLTRANSFERASES 1990 281 24 92%
The pivotal role of pyruvate dehydrogenase kinases in metabolic flexibility 2014 10 72 46%
The pyruvate dehydrogenase multi-enzyme complex from Gram-negative bacteria 1998 94 85 92%
2-oxo acid dehydrogenase multienzyme complexes. The central role of the lipoyl domain 1997 64 152 91%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 CHEM BIOL INTER E TRAINING PROGRAM 6 80% 0.2% 4
2 FUNDAMENTAL MED PHARMACEUT SCI 5 60% 0.3% 6
3 GEN DEV MED 3 30% 0.4% 8
4 PROT CHEM ENGN 3 22% 0.6% 11
5 METAB PROGRAMME 3 29% 0.4% 8
6 BIOCHEM BASIC MED SCI 2 50% 0.2% 3
7 BIOL PHYS SPACE 2 50% 0.2% 3
8 INHERITED DISORDERS ENERGY METAB 2 40% 0.2% 4
9 EXTREMOPHILE 2 16% 0.5% 10
10 MUSCLE METAB BIOPHYS 1 25% 0.3% 5

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000122444 MAPLE SYRUP URINE DISEASE//BRANCHED CHAIN ALPHA KETO ACID DEHYDROGENASE COMPLEX//BCKDHA
2 0.0000119541 GLYCINE REDUCTASE//EUBACTERIUM ACIDAMINOPHILUM//SARCOSINE REDUCTASE
3 0.0000111614 NONKETOTIC HYPERGLYCINEMIA//NON KETOTIC HYPERGLYCINEMIA//GLYCINE N ACYLTRANSFERASE
4 0.0000085925 TRANSKETOLASE//CARBOLIGATION//THIAMINE DIPHOSPHATE
5 0.0000084821 CYCLIC AMP ANTAGONIST//CYCLIC PIP//SCI PEDIAT ADOLESCENZA
6 0.0000073699 TYPE B LACTIC ACIDOSIS//SODIUM DICHLOROACETATE DCA//ACID BASE EQUILIBRIUM METABOLIC ACIDOSIS
7 0.0000060748 BIOTIN PROTEIN LIGASE//BIOTIN CARBOXYLASE//CARBOXYLTRANSFERASE
8 0.0000056372 TRYPANOTHIONE REDUCTASE//TRYPANOTHIONE//TRYPAREDOXIN
9 0.0000039656 ALPHA LIPOIC ACID//LIPOIC ACID//THIOCTIC ACID
10 0.0000036036 BIOTIN SYNTHASE//BIOTIN BIOSYNTHESIS//DETHIOBIOTIN SYNTHETASE