Class information for:
Level 1: BIS7 TACRINE//BUTYRYLCHOLINESTERASE//ACETYLCHOLINESTERASE INHIBITORS

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
3308 1938 40.3 72%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
1763 5876 BUTYRYLCHOLINESTERASE//ACETYLCHOLINESTERASE//BIS7 TACRINE

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 BIS7 TACRINE Author keyword 52 87% 1% 26
2 BUTYRYLCHOLINESTERASE Author keyword 35 18% 9% 173
3 ACETYLCHOLINESTERASE INHIBITORS Author keyword 20 21% 4% 85
4 PERIPHERAL SITE Author keyword 19 70% 1% 16
5 MULTI TARGET DIRECTED LIGANDS Author keyword 17 72% 1% 13
6 BUTYRYLCHOLINESTERASE INHIBITORS Author keyword 15 77% 1% 10
7 TACRINE Author keyword 14 17% 4% 75
8 FASCICULIN Author keyword 14 57% 1% 16
9 TACRINE ANALOGUES Author keyword 12 75% 0% 9
10 HUPRINES Author keyword 12 86% 0% 6

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 BIS7 TACRINE 52 87% 1% 26 Search BIS7+TACRINE Search BIS7+TACRINE
2 BUTYRYLCHOLINESTERASE 35 18% 9% 173 Search BUTYRYLCHOLINESTERASE Search BUTYRYLCHOLINESTERASE
3 ACETYLCHOLINESTERASE INHIBITORS 20 21% 4% 85 Search ACETYLCHOLINESTERASE+INHIBITORS Search ACETYLCHOLINESTERASE+INHIBITORS
4 PERIPHERAL SITE 19 70% 1% 16 Search PERIPHERAL+SITE Search PERIPHERAL+SITE
5 MULTI TARGET DIRECTED LIGANDS 17 72% 1% 13 Search MULTI+TARGET+DIRECTED+LIGANDS Search MULTI+TARGET+DIRECTED+LIGANDS
6 BUTYRYLCHOLINESTERASE INHIBITORS 15 77% 1% 10 Search BUTYRYLCHOLINESTERASE+INHIBITORS Search BUTYRYLCHOLINESTERASE+INHIBITORS
7 TACRINE 14 17% 4% 75 Search TACRINE Search TACRINE
8 FASCICULIN 14 57% 1% 16 Search FASCICULIN Search FASCICULIN
9 TACRINE ANALOGUES 12 75% 0% 9 Search TACRINE+ANALOGUES Search TACRINE+ANALOGUES
10 HUPRINES 12 86% 0% 6 Search HUPRINES Search HUPRINES

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 BETA AMYLOID AGGREGATION 150 76% 5% 104
2 ACTIVE SITE GORGE 117 72% 5% 91
3 ACETYLCHOLINESTERASE INHIBITORS 110 39% 12% 225
4 TARGET DIRECTED LIGANDS 110 82% 3% 64
5 PERIPHERAL SITE 108 67% 5% 98
6 FASCICULIN 69 67% 3% 62
7 BUTYRYLCHOLINESTERASE 66 26% 11% 219
8 PERIPHERAL ANIONIC SITE 66 62% 4% 69
9 TORPEDO CALIFORNICA 65 31% 9% 178
10 MULTIFUNCTIONAL AGENTS 64 88% 2% 30

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
A review on cholinesterase inhibitors for Alzheimer's disease 2013 43 106 70%
A review on coumarins as acetylcholinesterase inhibitors for Alzheimer's disease 2012 71 55 42%
Pyrano[3,2-c]quinoline-6-Chlorotacrine Hybrids as a Novel Family of Acetylcholinesterase- and beta-Amyloid-Directed Anti-Alzheimer Compounds 2009 74 97 80%
Recent advances in the multitarget-directed ligands approach for the treatment of Alzheimer's disease 2013 56 310 29%
Acetylcholinesterase inhibitors as Alzheimer therapy: From nerve toxins to neuroprotection 2013 30 149 47%
Acetylcholinesterase Inhibitors as Disease-Modifying Therapies for Alzheimer's Disease 2008 102 152 61%
Multifunctional compounds: Smart molecules for multifactorial diseases 2014 16 96 33%
Multi-Target-Directed Ligands in Alzheimer's Disease Treatment 2011 54 135 50%
Multi-target-directed ligands to combat neurodegenerative diseases 2008 301 210 20%
Recent developments in chotinesterases inhibitors for Alzheimer's disease treatment 2007 94 103 62%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 UNITE ENZYMOL 11 35% 1.4% 27
2 MAYO CANC 11 47% 0.9% 17
3 TEOFILO HERNANDO 6 17% 1.9% 36
4 TRADIT CHINESE MED PHARMACOL TOXICOL 6 80% 0.2% 4
5 FARMACOL TER EUT TOXICOL 6 21% 1.2% 23
6 AMRITA NANOSCI MOL MED ACNSMM 4 67% 0.2% 4
7 WUHAN NEUROSCI DRUG 4 67% 0.2% 4
8 LEHRSTUHL PHARMAZEUT MED CHEM 4 28% 0.7% 13
9 RAD LIB QUIM COMPUTAC IQOG 4 75% 0.2% 3
10 UNITAT ASSOCIADA CSIC 4 22% 0.8% 16

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000143552 ACETYLCHOLINESTERASE//BUTYRYLCHOLINESTERASE//MOLECULAR FORMS
2 0.0000134241 CIS DIAMMINEDIAQUAPLATINUM II//TURNOVER KINETICS//ARCHIBALD
3 0.0000113029 TACRINE//TETRAHYDROAMINOACRIDINE//METRIFONATE
4 0.0000108577 HUPERZINE A//LYCOPODIUM ALKALOIDS//HUPERZIA SERRATA
5 0.0000094575 COMPARATIVE ENZYMOLOGY//CARBOXYLESTERASE CAE//INSECTOACARICIDES
6 0.0000094201 K VARIANT//DIBUCAINE NUMBER//SERUM CHOLINESTERASE
7 0.0000089685 DONEPEZIL//RIVASTIGMINE//MEMANTINE
8 0.0000071081 BILE SALT DEPENDENT LIPASE//CHOLESTEROL ESTERASE//CARBAMATE INHIBITORS
9 0.0000067148 HI 6//SOMAN//OBIDOXIME
10 0.0000060513 CA2 ANTAGONISTIC ACTION//INNOVAT PATHOPHYSIOL GRP//RAT PHRENIC NERVE