Class information for:
Level 1: CYP2C9//VKORC1//WARFARIN

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
2863 2053 33.8 78%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
1107 9272 WARFARIN//CYP2C9//VKORC1

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 CYP2C9 Author keyword 412 63% 20% 420
2 VKORC1 Author keyword 382 81% 11% 233
3 WARFARIN Author keyword 142 19% 33% 675
4 CYP4F2 Author keyword 66 74% 2% 50
5 ACENOCOUMAROL Author keyword 56 48% 4% 87
6 CYP2C9 POLYMORPHISM Author keyword 26 87% 1% 13
7 CYTOCHROME P4502C9 Author keyword 23 69% 1% 20
8 DOSING ALGORITHM Author keyword 18 65% 1% 17
9 R WARFARIN Author keyword 18 83% 0% 10
10 CYP2C93 Author keyword 18 89% 0% 8

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 CYP2C9 412 63% 20% 420 Search CYP2C9 Search CYP2C9
2 VKORC1 382 81% 11% 233 Search VKORC1 Search VKORC1
3 WARFARIN 142 19% 33% 675 Search WARFARIN Search WARFARIN
4 CYP4F2 66 74% 2% 50 Search CYP4F2 Search CYP4F2
5 ACENOCOUMAROL 56 48% 4% 87 Search ACENOCOUMAROL Search ACENOCOUMAROL
6 CYP2C9 POLYMORPHISM 26 87% 1% 13 Search CYP2C9+POLYMORPHISM Search CYP2C9+POLYMORPHISM
7 CYTOCHROME P4502C9 23 69% 1% 20 Search CYTOCHROME+P4502C9 Search CYTOCHROME+P4502C9
8 DOSING ALGORITHM 18 65% 1% 17 Search DOSING+ALGORITHM Search DOSING+ALGORITHM
9 R WARFARIN 18 83% 0% 10 Search R+WARFARIN Search R+WARFARIN
10 CYP2C93 18 89% 0% 8 Search CYP2C93 Search CYP2C93

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 CYP2C9 309 58% 17% 353
2 CYTOCHROME P4502C9 276 70% 11% 229
3 VKORC1 203 71% 8% 163
4 K EPOXIDE REDUCTASE 142 61% 7% 150
5 DOSE REQUIREMENTS 102 48% 8% 154
6 CYP2C9 GENOTYPE 96 91% 2% 40
7 VKORC1 HAPLOTYPES 94 89% 2% 42
8 VKORC1 GENOTYPES 91 89% 2% 41
9 WARFARIN DOSE REQUIREMENTS 88 78% 3% 59
10 DOSING ALGORITHMS 86 96% 1% 26

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Oral anticoagulation: a critique of recent advances and controversies 2015 2 81 64%
Influence of CYP2C9 and VKORC1 on Patient Response to Warfarin: A Systematic Review and Meta-Analysis 2012 30 126 88%
Cytochrome P4502C9 polymorphisms: a comprehensive review of the in-vitro and human data 2002 357 70 87%
Prediction of warfarin dose: why, when and how? 2012 29 59 69%
Fever as a Risk Factor for Increased Response to Vitamin K Antagonists: A Review of the Evidence and Potential Mechanisms 2015 1 17 59%
Influence of CYP2C9 and VKORC1 genotypes on the risk of hemorrhagic complications in warfarin-treated patients: A systematic review and meta-analysis 2013 20 70 77%
Pharmacogenetics of Warfarin 2010 42 41 93%
Impact of VKORC1 gene polymorphism on interindividual and interethnic warfarin dosage requirement- A systematic review and meta analysis 2010 37 36 100%
Impact of the CYP4F2 p.V433M Polymorphism on Coumarin Dose Requirement: Systematic Review and Meta-Analysis 2012 18 48 88%
Association of warfarin dose with genes involved in its action and metabolism 2007 184 60 50%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 UNITE GERIATRIE AIGUE 2 44% 0.2% 4
2 DRUG SAFETY UNIT 2 14% 0.7% 15
3 PERSONALIZED GENET MED 2 67% 0.1% 2
4 ANTICOAGULAT CLIN 2 22% 0.4% 8
5 GENOME QUEBEC MONTREAL HEART 2 43% 0.1% 3
6 ST ANTOINE UNIV HOSP 2 28% 0.2% 5
7 ANTICOAGULAT 1 100% 0.1% 2
8 CLIN PHARM CLIN CHEM HAEMATOL 1 100% 0.1% 2
9 METHODIST INPATIENT PHYS 1 100% 0.1% 2
10 MULTIDISCIPLINARY MOL BIOL DIAGNOST 1 100% 0.1% 2

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000167030 INTERNATIONAL SENSITIVITY INDEX//PROTHROMBIN TIME//INTERNATIONAL NORMALIZED RATIO
2 0.0000127339 ANTICOAGULANT RESISTANCE//VERTEBRATE PESTS UNIT//VKOR
3 0.0000116441 PROTHROMBIN COMPLEX CONCENTRATE//PROTHROMBIN COMPLEX CONCENTRATES//ANTICOAGULATION REVERSAL
4 0.0000101776 PHARMACOGENOMICS//PERSONALIZED MEDICINE//PROGRAM PERSONALIZED MED TARGETED THER EUT
5 0.0000081511 CYP2D6//DEBRISOQUINE//CYP2C19
6 0.0000069367 ATRIAL FIBRILLATION//WARFARIN//CITY HOSP
7 0.0000062912 CYP3A//COCKTAIL//MECHANISM BASED INHIBITION
8 0.0000057254 POTENTIAL DRUG DRUG INTERACTION//POTENTIAL DRUG DRUG INTERACTIONS//PRESCRIPTIONS SCREENING
9 0.0000053691 ANTICOAGULANT RODENTICIDES//SUPERWARFARIN//BRODIFACOUM
10 0.0000050160 SITE OF METABOLISM//ACTIVE SITE TOPOLOGY//COMPUTAT CHEM MOL STRUCT