Class information for:
Level 1: TPL2//TPL 2//TPL2 KINASE

Basic class information

ID Publications Average number
of references
Avg. shr. active
ref. in WoS
27310 191 45.2 94%



Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)



ID, lev.
above
Publications Label for level above
1412 7537 COFFIN LOWRY SYNDROME//ERK5//JNK

Terms with highest relevance score



Rank Term Type of term Relevance score
(tfidf)
Class's shr.
of term's tot.
occurrences
Shr. of publ.
in class containing
term
Num. of
publ. in
class
1 TPL2 Author keyword 19 80% 6% 12
2 TPL 2 Author keyword 14 100% 4% 7
3 TPL2 KINASE Author keyword 8 100% 3% 5
4 TUMOR PROGRESSION LOCUS 2 Author keyword 6 80% 2% 4
5 MAP3K8 Author keyword 6 58% 4% 7
6 COT TPL2 Author keyword 6 100% 2% 4
7 TP12 Author keyword 6 100% 2% 4
8 COT Author keyword 5 30% 7% 13
9 INFLAMMAT SIGNALING Address 4 75% 2% 3
10 MAP3 KINASE Author keyword 2 67% 1% 2

Web of Science journal categories

Author Key Words



Rank Web of Science journal category Relevance score
(tfidf)
Class's shr.
of term's tot.
occurrences
Shr. of publ.
in class containing
term
Num. of
publ. in
class
LCSH search Wikipedia search
1 TPL2 19 80% 6% 12 Search TPL2 Search TPL2
2 TPL 2 14 100% 4% 7 Search TPL+2 Search TPL+2
3 TPL2 KINASE 8 100% 3% 5 Search TPL2+KINASE Search TPL2+KINASE
4 TUMOR PROGRESSION LOCUS 2 6 80% 2% 4 Search TUMOR+PROGRESSION+LOCUS+2 Search TUMOR+PROGRESSION+LOCUS+2
5 MAP3K8 6 58% 4% 7 Search MAP3K8 Search MAP3K8
6 COT TPL2 6 100% 2% 4 Search COT+TPL2 Search COT+TPL2
7 TP12 6 100% 2% 4 Search TP12 Search TP12
8 COT 5 30% 7% 13 Search COT Search COT
9 MAP3 KINASE 2 67% 1% 2 Search MAP3+KINASE Search MAP3+KINASE
10 CANCER OSAKA THYROID COT 1 100% 1% 2 Search CANCER+OSAKA+THYROID+COT Search CANCER+OSAKA+THYROID+COT

Key Words Plus



Rank Web of Science journal category Relevance score
(tfidf)
Class's shr.
of term's tot.
occurrences
Shr. of publ.
in class containing
term
Num. of
publ. in
class
1 NF KAPPA B1 P105 38 60% 22% 42
2 TPL 2 38 84% 11% 21
3 ACTIVATE ERK 24 91% 5% 10
4 TPL2 ACTIVATION 20 100% 5% 9
5 TPL2 KINASE 12 75% 5% 9
6 LIPOPOLYSACCHARIDE ACTIVATION 11 54% 7% 14
7 TUMOR PROGRESSION LOCUS 2 8 100% 3% 5
8 COT ONCOGENE 6 71% 3% 5
9 COT KINASE 3 100% 2% 3
10 COT PROTOONCOGENE 3 100% 2% 3

Journals

Reviews



Title Publ. year Cit. Active references % act. ref.
to same field
Tp12 kinase signal transduction in inflammation and cancer 2011 28 80 75%
Cot/Tpl-2 Protein Kinase as a Target for the Treatment of Inflammatory Disease 2009 21 41 98%
Regulation and function of TPL-2, an I kappa B kinase-regulated MAP kinase kinase kinase 2011 34 100 57%
I kappa B kinase regulation of the TPL-2/ERK MAPK pathway 2012 28 118 47%
Coordinating TLR-activated signaling pathways in cells of the immune system 2007 70 64 30%
TPL2 signalling: From Toll-like receptors-mediated ERK1/ERK2 activation to Cystic Fibrosis lung disease 2014 1 51 57%
TPL-2/COT AND COX-2 IN BREAST CANCER 2008 15 42 45%
Tumor Progression Locus 2 (Tpl2) Kinase as a Novel Therapeutic Target for Cancer: Double-Sided Effects of Tpl2 on Cancer 2015 0 142 57%
MAP kinase kinase kinases and innate immunity 2006 64 81 16%
Macrophages in multiple myeloma: emerging concepts and therapeutic implications 2013 3 137 15%

Address terms



Rank Address term Relevance score
(tfidf)
Class's shr.
of term's tot.
occurrences
Shr. of publ.
in class containing
term
Num. of
publ.
in class
1 INFLAMMAT SIGNALING 4 75% 1.6% 3
2 TEAM MOL CELLULAR PHYSIOPATHOL OBES DIABET 7 1 50% 1.0% 2
3 CLIN MED CHINESE WESTERN MED 1 50% 0.5% 1
4 GENOM METAB DIS 1 50% 0.5% 1
5 PROGRAM MOL BIOL BIOMED 1 50% 0.5% 1
6 PROT STRUCTURE 1 50% 0.5% 1
7 FOOD SCI BIOTECHNOL PROGRAM 1 25% 1.0% 2
8 CONSEJO SUPER INVEST CIENT MED 0 33% 0.5% 1
9 DRUG SAFETY METABOL 0 33% 0.5% 1
10 PROT PHOSPHORYLAT UNITMRC 0 33% 0.5% 1

Related classes at same level (level 1)



Rank Relatedness score Related classes
1 0.0000093032 TAK1//TRAF4//TRAF5
2 0.0000081481 I KAPPA B//IKK//C REL
3 0.0000074086 BATRACYLIN//2 LITHIOMETHYLPHENYL ISOCYANIDE//4H 3 1 BENZOXAZINES
4 0.0000072108 MK2//MAPKAP K2//MK5
5 0.0000070284 A20//STRESS ASSOCIATED PROTEIN//ZINC FINGER PROTEIN A20
6 0.0000062567 ERK5//MEK5//EXTRACELLULAR SIGNAL REGULATED KINASE 5 ERK5
7 0.0000061974 TIR DOMAIN//PELLINO//INNATE IMMUN INFLAMMAT
8 0.0000059769 RAF//RAF 1//LEO JENKINS CANC
9 0.0000058899 PIM 2//PIM 1//PIM 3
10 0.0000048541 JNK//MKK4//JNK3