Class information for:
Level 1: PROSTAGLANDIN H SYNTHASE//IMRECOXIB//AB HANCOCK JR MEM CANC

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
2477 2163 37.2 77%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
670 12541 CYCLOOXYGENASE 2//COX 2//CYCLOOXYGENASE

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 PROSTAGLANDIN H SYNTHASE Author keyword 15 31% 2% 41
2 IMRECOXIB Author keyword 12 86% 0% 6
3 AB HANCOCK JR MEM CANC Address 10 35% 1% 24
4 1 5 DIARYLPYRAZOLES Author keyword 10 61% 1% 11
5 COX 1 Author keyword 9 16% 2% 52
6 COX 2 INHIBITORS Author keyword 9 15% 2% 53
7 SELECTIVE COX 2 INHIBITORS Author keyword 6 30% 1% 18
8 CYCLOOXYGENASE 1 Author keyword 6 15% 2% 37
9 PROSTAGLANDIN ENDOPEROXIDE SYNTHASE Author keyword 6 25% 1% 21
10 CYCLOOXYGENASE 1 AND 2 INHIBITION Author keyword 6 100% 0% 4

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 PROSTAGLANDIN H SYNTHASE 15 31% 2% 41 Search PROSTAGLANDIN+H+SYNTHASE Search PROSTAGLANDIN+H+SYNTHASE
2 IMRECOXIB 12 86% 0% 6 Search IMRECOXIB Search IMRECOXIB
3 1 5 DIARYLPYRAZOLES 10 61% 1% 11 Search 1+5+DIARYLPYRAZOLES Search 1+5+DIARYLPYRAZOLES
4 COX 1 9 16% 2% 52 Search COX+1 Search COX+1
5 COX 2 INHIBITORS 9 15% 2% 53 Search COX+2+INHIBITORS Search COX+2+INHIBITORS
6 SELECTIVE COX 2 INHIBITORS 6 30% 1% 18 Search SELECTIVE+COX+2+INHIBITORS Search SELECTIVE+COX+2+INHIBITORS
7 CYCLOOXYGENASE 1 6 15% 2% 37 Search CYCLOOXYGENASE+1 Search CYCLOOXYGENASE+1
8 PROSTAGLANDIN ENDOPEROXIDE SYNTHASE 6 25% 1% 21 Search PROSTAGLANDIN+ENDOPEROXIDE+SYNTHASE Search PROSTAGLANDIN+ENDOPEROXIDE+SYNTHASE
9 CYCLOOXYGENASE 1 AND 2 INHIBITION 6 100% 0% 4 Search CYCLOOXYGENASE+1+AND+2+INHIBITION Search CYCLOOXYGENASE+1+AND+2+INHIBITION
10 PROSTAGLANDIN H SYNTHASE 2 5 41% 0% 9 Search PROSTAGLANDIN+H+SYNTHASE+2 Search PROSTAGLANDIN+H+SYNTHASE+2

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 H SYNTHASE 110 56% 6% 134
2 ENDOPEROXIDE SYNTHASE 104 51% 7% 145
3 G H SYNTHASE 78 53% 5% 104
4 1 2 DIARYLCYCLOPENTENES 60 100% 1% 20
5 CYCLOOXYGENASE ACTIVE SITE 56 80% 2% 35
6 H 2 SYNTHASE 46 82% 1% 27
7 PEROXIDASE REACTION 45 62% 2% 46
8 PROSTAGLANDIN ENDOPEROXIDE SYNTHASE 43 30% 6% 121
9 HIGHER OXIDATION STATES 43 40% 4% 83
10 SHEEP VESICULAR GLAND 42 75% 1% 30

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Cyclooxygenases: Structural, cellular, and molecular biology 2000 1594 247 49%
Cyclooxygenases 1 and 2 1998 1863 104 43%
Prostaglandin endoperoxide H synthases (cyclooxygenases)-1 and -2 1996 1433 66 79%
Structural and functional basis of cyclooxygenase inhibition 2007 107 91 71%
Cyclooxygenase isozymes: The biology of prostaglandin synthesis and inhibition 2004 659 446 26%
Cyclooxygenase inhibitors - current status and future prospects 2001 366 91 64%
Arachidonic acid oxygenation by COX-1 and COX-2 - Mechanisms of catalysis and inhibition 1999 281 50 86%
Prostaglandin synthase 2 1996 981 115 66%
Evolution of nonsteroidal anti-inflammatory drugs (NSAIDs): Cyclooxygenase (COX) inhibition and beyond 2008 139 125 44%
Bacterial and algal orthologs of prostaglandin H-2 synthase: novel insights into the evolution of an integral membrane protein 2015 1 109 61%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 AB HANCOCK JR MEM CANC 10 35% 1.1% 24
2 DIPARTIMENTO STUDI CHIM TECNOL FARMACO 5 63% 0.2% 5
3 HLTH SCI INTERNAL MED HEMATOL 4 75% 0.1% 3
4 MOL BIOL 341 4 75% 0.1% 3
5 VANDERBILT CHEM BIOL MOL TOXICOL MED 3 60% 0.1% 3
6 RADIOPHARMACEUT CHEM BIOL 2 36% 0.2% 5
7 PHYSIOL CHEMBUNKYO KU 2 67% 0.1% 2
8 VANDERBILT CHEM BIO HANCOCK JR MEM C 2 67% 0.1% 2
9 VANDERBILT CHEM BIOL MOL TOXICOL BI 2 67% 0.1% 2
10 VANDERBILT CHEM BIOL MOL TOXICOL CH 2 67% 0.1% 2

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000169818 SALICYLIDENEAMINO 2 THIOPHENOL//GAMABUFOTALIN//INFLAMMATION CONTROL
2 0.0000164030 NIMESULIDE//CAS 51803 78 2//AULINR
3 0.0000132194 GEORGE M OBRIEN KIDNEY UROL DIS//GEORGE OBRIEN KIDNEY UROL DIS//SERV 151 E
4 0.0000125484 EXPT THER EUT PHARMACOINFORMAT//PROSTACYCLIN SYNTHASE GENE//PROSTACYCLIN SYNTHASE
5 0.0000112068 NEUROINFLAMMAT S//MOL NEUROSCI UNIT//BUTAPROST
6 0.0000109578 MPGES 1//PROSTAGLANDIN E SYNTHASE//MPGES 2
7 0.0000093116 CYCLOOXYGENASE 2//COX 2//CELECOXIB
8 0.0000083826 CYCLOOXYGENASE 2 GENE//PTGS2//COX 2 GENE
9 0.0000082723 NSAIDS//COXIBS//ROFECOXIB
10 0.0000082536 NO ASPIRIN//NITROASPIRIN//NCX 4016