Class information for:
Level 1: FARNESOID X RECEPTOR//FXR//TGR5

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
2254 2234 45.6 81%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
910 10558 BILE ACIDS//FARNESOID X RECEPTOR//CEREBROTENDINOUS XANTHOMATOSIS

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 FARNESOID X RECEPTOR Author keyword 172 66% 7% 161
2 FXR Author keyword 98 58% 5% 115
3 TGR5 Author keyword 87 79% 3% 56
4 BILE ACID SYNTHESIS Author keyword 67 61% 3% 71
5 CHOLESTEROL 7 ALPHA HYDROXYLASE Author keyword 65 47% 5% 103
6 SMALL HETERODIMER PARTNER Author keyword 33 67% 1% 29
7 BILE ACIDS Author keyword 30 12% 10% 226
8 STEROL 12 ALPHA HYDROXYLASE Author keyword 26 100% 0% 11
9 CYP7A1 Author keyword 26 41% 2% 50
10 FARNESOID X RECEPTOR FXR Author keyword 23 64% 1% 23

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 FARNESOID X RECEPTOR 172 66% 7% 161 Search FARNESOID+X+RECEPTOR Search FARNESOID+X+RECEPTOR
2 FXR 98 58% 5% 115 Search FXR Search FXR
3 TGR5 87 79% 3% 56 Search TGR5 Search TGR5
4 BILE ACID SYNTHESIS 67 61% 3% 71 Search BILE+ACID+SYNTHESIS Search BILE+ACID+SYNTHESIS
5 CHOLESTEROL 7 ALPHA HYDROXYLASE 65 47% 5% 103 Search CHOLESTEROL+7+ALPHA+HYDROXYLASE Search CHOLESTEROL+7+ALPHA+HYDROXYLASE
6 SMALL HETERODIMER PARTNER 33 67% 1% 29 Search SMALL+HETERODIMER+PARTNER Search SMALL+HETERODIMER+PARTNER
7 BILE ACIDS 30 12% 10% 226 Search BILE+ACIDS Search BILE+ACIDS
8 STEROL 12 ALPHA HYDROXYLASE 26 100% 0% 11 Search STEROL+12+ALPHA+HYDROXYLASE Search STEROL+12+ALPHA+HYDROXYLASE
9 CYP7A1 26 41% 2% 50 Search CYP7A1 Search CYP7A1
10 FARNESOID X RECEPTOR FXR 23 64% 1% 23 Search FARNESOID+X+RECEPTOR+FXR Search FARNESOID+X+RECEPTOR+FXR

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 FARNESOID X RECEPTOR 242 47% 17% 377
2 FXR 240 70% 9% 200
3 BILE ACID RECEPTOR 162 80% 4% 99
4 NEGATIVE FEEDBACK REGULATION 145 60% 7% 158
5 CHOLESTEROL 7 ALPHA HYDROXYLASE GENE 80 57% 4% 94
6 CHOLESTEROL 7 ALPHA HYDROXYLASE 76 40% 7% 148
7 ORGANIC SOLUTE TRANSPORTER 67 73% 2% 51
8 ORPHAN NUCLEAR RECEPTOR 61 24% 10% 225
9 SMALL HETERODIMER PARTNER 60 45% 5% 101
10 BILE ACID SYNTHESIS 54 28% 7% 161

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Bile acid signaling and liver regeneration 2015 7 73 62%
Bile acid receptors as targets for drug development 2014 36 159 57%
Targeting bile-acid signalling for metabolic diseases 2008 288 145 71%
Farnesoid X receptor: a master regulator of hepatic triglyceride and glucose homeostasis 2015 4 60 72%
Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation 2009 386 342 54%
Bile acids: regulation of synthesis 2009 217 147 72%
Tissue-specific actions of FXR in metabolism and cancer 2015 3 141 62%
The bile acid TGR5 membrane receptor: From basic research to clinical application 2014 16 84 60%
Bile acid receptors as targets for the treatment of dyslipidemia and cardiovascular disease 2012 54 157 73%
Beyond intestinal soap-bile acids in metabolic control 2014 13 125 64%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 GENE REGULAT DRUG DISCOVERY 12 49% 0.8% 18
2 PHARMACEUT DEV PHYS PROPERTIES DEVELOPABIL 9 83% 0.2% 5
3 GI 15A 8 70% 0.3% 7
4 EXPT MOL HEPATOL 6 27% 0.9% 20
5 DIPARTIMENTO SCI CHIRURG BIOMED 4 75% 0.1% 3
6 METAB DRUG DISCOVERY 4 75% 0.1% 3
7 UNITE RECH 545 4 56% 0.2% 5
8 BIOCHEM MOL PATHOL 4 15% 1.1% 25
9 INTEGRAT MED SCI 4 11% 1.4% 32
10 CARDIOVASC METAB DIS DISCOVERY 3 100% 0.1% 3

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000185100 BILE ACID MALABSORPTION//SEHCAT//75SEHCAT
2 0.0000155827 INTRAHEPATIC CHOLESTASIS OF PREGNANCY//PROGRESSIVE FAMILIAL INTRAHEPATIC CHOLESTASIS//ABCB11
3 0.0000129669 CALCULUS BOVIS//SULFATED BILE ACID//URINARY SULFATED BILE ACID
4 0.0000105468 FGF 21//FIBROBLAST GROWTH FACTOR 21//BETA KLOTHO
5 0.0000100720 URSODEOXYCHOLIC ACID//TAUROURSODEOXYCHOLIC ACID//TAUROURSODEOXYCHOLATE
6 0.0000098035 LIVER X RECEPTOR//LXR//LIVER X RECEPTORS
7 0.0000097004 CEREBROTENDINOUS XANTHOMATOSIS//CHOLESTANOL//BILE ALCOHOLS
8 0.0000085002 PREGNANE X RECEPTOR//PXR//CONSTITUTIVE ANDROSTANE RECEPTOR
9 0.0000075187 ALIMENTARY HYPERCHOLESTEROLEMIA//ACTIVATION OF NEUTROPHILS//AT III DEFICIENCY
10 0.0000070403 GUGGULSTERONE//COMMIPHORA WIGHTII//COMMIPHORA MYRRHA