Class information for:
Level 1: HIV 1 PROTEASE//HIV PROTEASE//KNI 272

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
2208 2247 37.2 82%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
2929 2247 HIV 1 PROTEASE//HIV PROTEASE//KNI 272

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 HIV 1 PROTEASE Author keyword 170 58% 9% 198
2 HIV PROTEASE Author keyword 66 52% 4% 90
3 KNI 272 Author keyword 26 100% 0% 11
4 HIV 1 PROTEINASE Author keyword 21 85% 0% 11
5 HIV 1 PROTEASE INHIBITORS Author keyword 19 44% 2% 34
6 HIV 1 PROTEASE INHIBITOR Author keyword 19 52% 1% 26
7 EXPT RETROVIROL SECT Address 19 35% 2% 44
8 MOL BASIS DIS PROGRAM Address 15 48% 1% 23
9 HIV PROTEINASE Author keyword 15 71% 1% 12
10 RETROVIRAL PROTEASE Author keyword 14 60% 1% 15

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 HIV 1 PROTEASE 170 58% 9% 198 Search HIV+1+PROTEASE Search HIV+1+PROTEASE
2 HIV PROTEASE 66 52% 4% 90 Search HIV+PROTEASE Search HIV+PROTEASE
3 KNI 272 26 100% 0% 11 Search KNI+272 Search KNI+272
4 HIV 1 PROTEINASE 21 85% 0% 11 Search HIV+1+PROTEINASE Search HIV+1+PROTEINASE
5 HIV 1 PROTEASE INHIBITORS 19 44% 2% 34 Search HIV+1+PROTEASE+INHIBITORS Search HIV+1+PROTEASE+INHIBITORS
6 HIV 1 PROTEASE INHIBITOR 19 52% 1% 26 Search HIV+1+PROTEASE+INHIBITOR Search HIV+1+PROTEASE+INHIBITOR
7 HIV PROTEINASE 15 71% 1% 12 Search HIV+PROTEINASE Search HIV+PROTEINASE
8 RETROVIRAL PROTEASE 14 60% 1% 15 Search RETROVIRAL+PROTEASE Search RETROVIRAL+PROTEASE
9 DIMERIZATION INHIBITORS 13 80% 0% 8 Search DIMERIZATION+INHIBITORS Search DIMERIZATION+INHIBITORS
10 OLIGOPEPTIDE SUBSTRATES 12 86% 0% 6 Search OLIGOPEPTIDE+SUBSTRATES Search OLIGOPEPTIDE+SUBSTRATES

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 RETROVIRAL PROTEASES 264 73% 9% 203
2 TYPE 1 PROTEASE 170 61% 8% 179
3 IMMUNODEFICIENCY VIRUS PROTEASE 94 45% 7% 160
4 SYNTHETIC HIV 1 PROTEASE 74 66% 3% 69
5 VIRUS TYPE 1 PROTEASE 60 51% 4% 84
6 ORALLY BIOAVAILABLE INHIBITOR 59 50% 4% 86
7 IMMUNODEFICIENCY VIRUS 1 PROTEASE 53 65% 2% 51
8 HIV 1 PROTEASE 50 18% 11% 254
9 ELUCIDATE DETAILS 49 94% 1% 17
10 VIRAL INFECTIVITY 48 29% 6% 143

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
STRUCTURE-BASED INHIBITORS OF HIV-1 PROTEASE 1993 631 69 84%
Inhibitors of HIV-1 protease: A major success of structure-assisted drug design 1998 405 121 74%
Design of HIV protease inhibitors targeting protein backbone: An effective strategy for combating drug resistance 2008 80 34 74%
HIV-protease inhibitors 1998 577 48 40%
Targeting structural flexibility in HIV-1 protease inhibitor binding 2007 67 59 83%
Enhancing Protein Backbone BindinguA Fruitful Concept for Combating Drug-Resistant HIV 2012 18 103 66%
Structural and biochemical studies of retroviral proteases 2000 123 93 94%
THE HIV-1 PROTEASE AS A THERAPEUTIC TARGET FOR AIDS 1992 312 113 75%
Recent Developments of Peptidomimetic HIV-1 Protease Inhibitors 2011 14 58 83%
Adaptive inhibitors of the HIV-1 protease 2005 73 33 64%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 EXPT RETROVIROL SECT 19 35% 2.0% 44
2 MOL BASIS DIS PROGRAM 15 48% 1.0% 23
3 HIV AIDS MALIGNANCY BRANCH 8 16% 2.1% 48
4 STRUCT BIOCHEM PROGRAM 8 42% 0.7% 15
5 BIOL MOL BASIS DIS 6 80% 0.2% 4
6 GENE MANIPULAT 6 58% 0.3% 7
7 BIOCALORIMETRY 5 32% 0.5% 12
8 SPECIAL PROGRAM PROT CHEM 4 67% 0.2% 4
9 BIOSCI BIOTECHNOL MIDORI KU 3 57% 0.2% 4
10 MOL VIROL CARCINOGENESIS 3 43% 0.3% 6

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000097624 K65R//TRANSMITTED DRUG RESISTANCE//HIV 1 DRUG RESISTANCE
2 0.0000094928 PREUSSIN//HAPALOSIN//ALPHA AMINO ALDEHYDES
3 0.0000072299 VIRUS CELL INTERACT SECT//GAG//M PMV
4 0.0000069324 CATHEPSIN E//ASPARTIC PROTEINASE//PEPSINOGEN C
5 0.0000065565 ATAZANAVIR//RITONAVIR//LOPINAVIR
6 0.0000055741 ENVIRONM IND CHEM//ONE STEP PERTURBATION//SAMPL4
7 0.0000043986 JOURNAL OF CHEMICAL INFORMATION AND MODELING//VIRTUAL SCREENING//JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN
8 0.0000042606 NNRTIS//REVERSE TRANSCRIPTASE//HIV 1 REVERSE TRANSCRIPTASE
9 0.0000034706 CRUZAIN//PLASMEPSIN//CRUZIPAIN
10 0.0000030314 BENZHYDRYLPIPERAZINE//1 BENZHYDRYL PIPERAZINE//1 BENZHYDRYL PIPERAZINE DERIVATIVES