Class information for:
Level 1: HOMOCYSTINURIA//CYSTATHIONINE BETA SYNTHASE//CYSTATHIONINE BETA SYNTHASE DEFICIENCY

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
21885 345 28.8 68%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
322 17515 HOMOCYSTEINE//FOLATE//FOLIC ACID

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 HOMOCYSTINURIA Author keyword 29 31% 23% 78
2 CYSTATHIONINE BETA SYNTHASE Author keyword 11 19% 15% 51
3 CYSTATHIONINE BETA SYNTHASE DEFICIENCY Author keyword 9 55% 3% 12
4 CBS Author keyword 2 13% 5% 16
5 DIRECT NUCLEOTIDE SEQUENCING Author keyword 2 67% 1% 2
6 CYSTATHIONINE BETA SYNTHASE CBS Author keyword 2 27% 2% 6
7 CYSTATHIONINE Author keyword 2 14% 3% 12
8 COLORADO INTELLECTUAL DEV DISABIL IDDRC Address 2 33% 1% 4
9 CYSTATHIONINE BETA SYNTHASE GENETIC VARIANTS Author keyword 1 100% 1% 2
10 CYSTATHIONINE BETA SYNTHETASE DEFICIENCY Author keyword 1 100% 1% 2

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 HOMOCYSTINURIA 29 31% 23% 78 Search HOMOCYSTINURIA Search HOMOCYSTINURIA
2 CYSTATHIONINE BETA SYNTHASE 11 19% 15% 51 Search CYSTATHIONINE+BETA+SYNTHASE Search CYSTATHIONINE+BETA+SYNTHASE
3 CYSTATHIONINE BETA SYNTHASE DEFICIENCY 9 55% 3% 12 Search CYSTATHIONINE+BETA+SYNTHASE+DEFICIENCY Search CYSTATHIONINE+BETA+SYNTHASE+DEFICIENCY
4 CBS 2 13% 5% 16 Search CBS Search CBS
5 DIRECT NUCLEOTIDE SEQUENCING 2 67% 1% 2 Search DIRECT+NUCLEOTIDE+SEQUENCING Search DIRECT+NUCLEOTIDE+SEQUENCING
6 CYSTATHIONINE BETA SYNTHASE CBS 2 27% 2% 6 Search CYSTATHIONINE+BETA+SYNTHASE+CBS Search CYSTATHIONINE+BETA+SYNTHASE+CBS
7 CYSTATHIONINE 2 14% 3% 12 Search CYSTATHIONINE Search CYSTATHIONINE
8 CYSTATHIONINE BETA SYNTHASE GENETIC VARIANTS 1 100% 1% 2 Search CYSTATHIONINE+BETA+SYNTHASE+GENETIC+VARIANTS Search CYSTATHIONINE+BETA+SYNTHASE+GENETIC+VARIANTS
9 CYSTATHIONINE BETA SYNTHETASE DEFICIENCY 1 100% 1% 2 Search CYSTATHIONINE+BETA+SYNTHETASE+DEFICIENCY Search CYSTATHIONINE+BETA+SYNTHETASE+DEFICIENCY
10 31 BP VNTR 1 50% 0% 1 Search 31+BP+VNTR Search 31+BP+VNTR

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 ACTIVE CORE 23 86% 3% 12
2 NONRESPONSIVE HOMOCYSTINURIA 21 90% 3% 9
3 PYRIDOXINE RESPONSIVE HOMOCYSTINURIA 21 85% 3% 11
4 INTRASTERIC INHIBITION 20 100% 3% 9
5 LIGAND SWITCH 18 89% 2% 8
6 CBS MUTATIONS 17 100% 2% 8
7 HOMOCYSTINURIA 13 14% 25% 85
8 HEMOPROTEIN H 450 12 86% 2% 6
9 HEME PROTEIN 9 19% 13% 44
10 3 MUTATIONS 8 70% 2% 7

Journals

Reviews


Title Publ. year Cit. Active
references		 % act. ref.
to same field
A revisit to the natural history of homocystinuria due to cystathionine beta-synthase deficiency 2010 30 13 85%
Cystathionine beta-synthase: Structure, function, regulation, and location of homocystinuria-causing mutations 2004 91 44 75%
Redox regulation and reaction mechanism of human cystathionine-beta-synthase: a PLP-dependent hemesensor protein 2005 105 62 60%
Properties of an unusual heme cofactor in PLP-dependent cystathionine beta-synthase 2007 28 57 53%
Structural insights into pathogenic mutations in heme-dependent cystathionine-beta-synthase 2006 13 43 74%
The role of cystathionine beta-synthase in homocysteine metabolism 2005 43 63 52%
Newborn screening for homocystinuria 2011 1 8 50%
Newborn screening for homocystinuria 2013 0 9 56%
The enzymology of cystathionine biosynthesis: strategies for the control of substrate and reaction specificity 2005 28 83 30%
CYSTATHIONINE BETA-SYNTHASE (HUMAN) 1987 42 3 67%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ.
in class
1 COLORADO INTELLECTUAL DEV DISABIL IDDRC 2 33% 1.2% 4
2 PEDIAT CELLULAR STRUCT BIOL 1 50% 0.6% 2
3 IBUBCIBERERISCIII 1 50% 0.3% 1
4 PRINCE HENRY HOSP CARDIOVASC MED 1 50% 0.3% 1
5 S GIOVANNI CALIBITA FBF 1 50% 0.3% 1
6 UNITA OPERAT ANGIOL 1 50% 0.3% 1
7 UNITE MALAD HEREDITAI METAB 1 50% 0.3% 1
8 UNIDAD NUTR METABOLOPATIAS 1 22% 0.6% 2
9 CANC GENET SIGNALING PROGRAM 0 20% 0.6% 2
10 CONSULTORIOS EXTERNOS 0 33% 0.3% 1

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000170596 HOMOCYSTEINE//HYPERHOMOCYSTEINEMIA//FOLATE
2 0.0000149120 HEME SENSOR//FIXL//COOA
3 0.0000122157 HYDROGEN SULFIDE//CYSTATHIONINE GAMMA LYASE//DL PROPARGYLGLYCINE
4 0.0000113632 ABT KLIN CHEM MED//BONE ARTHRIT CBAR GERIATR MED//DESIGNING FOODS IMPROVE NUTR FOOD SCI HUMAN
5 0.0000105842 SULFUR REGULATION//HOMOCYSTEINE SYNTHASE//CYS3
6 0.0000083664 METHIONINE ADENOSYLTRANSFERASE//S ADENOSYLMETHIONINE//GLYCINE N METHYLTRANSFERASE
7 0.0000076769 METHYLMALONIC ACIDEMIA//PROPIONIC ACIDEMIA//METHYLMALONIC ACIDURIA
8 0.0000071882 TRYPTOPHAN SYNTHASE//INDOLE 3 GLYCEROL PHOSPHATE SYNTHASE//SECT ENZYME STRUCT FUNCT
9 0.0000064400 ASPARTATE AMINOTRANSFERASE//AROMATIC AMINO ACID AMINOTRANSFERASE//PYRIDOXAL 5 PHOSPHATE
10 0.0000058696 AMINOETHYLCYSTEINE KETIMINE DECARBOXYLATED DIMER//THIALYSINE//AMINOETHYLCYSTEINE KETIMINE DIMER