Class information for:
Level 1: METHIONINE DEPENDENCE//METHIONINASE//L METHIONINE GAMMA LYASE

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
21453 360 32.9 61%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
2787 2596 DIHYDRODIPICOLINATE SYNTHASE//ASPARTATE KINASE//METHIONINE DEPENDENCE

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 METHIONINE DEPENDENCE Author keyword 45 94% 4% 16
2 METHIONINASE Author keyword 41 90% 5% 18
3 L METHIONINE GAMMA LYASE Author keyword 18 89% 2% 8
4 METHIONINE GAMMA LYASE Author keyword 10 63% 3% 10
5 METHIONINE DEPLETION Author keyword 8 100% 1% 5
6 RECOMBINANT METHIONINASE Author keyword 6 80% 1% 4
7 L METHIONINASE Author keyword 6 100% 1% 4
8 METHIONINE FREE DIET Author keyword 6 100% 1% 4
9 POLYHEMOGLOBIN TYROSINASE Author keyword 3 100% 1% 3
10 MED SERV 111H Address 3 50% 1% 4

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 METHIONINE DEPENDENCE 45 94% 4% 16 Search METHIONINE+DEPENDENCE Search METHIONINE+DEPENDENCE
2 METHIONINASE 41 90% 5% 18 Search METHIONINASE Search METHIONINASE
3 L METHIONINE GAMMA LYASE 18 89% 2% 8 Search L+METHIONINE+GAMMA+LYASE Search L+METHIONINE+GAMMA+LYASE
4 METHIONINE GAMMA LYASE 10 63% 3% 10 Search METHIONINE+GAMMA+LYASE Search METHIONINE+GAMMA+LYASE
5 METHIONINE DEPLETION 8 100% 1% 5 Search METHIONINE+DEPLETION Search METHIONINE+DEPLETION
6 RECOMBINANT METHIONINASE 6 80% 1% 4 Search RECOMBINANT+METHIONINASE Search RECOMBINANT+METHIONINASE
7 L METHIONINASE 6 100% 1% 4 Search L+METHIONINASE Search L+METHIONINASE
8 METHIONINE FREE DIET 6 100% 1% 4 Search METHIONINE+FREE+DIET Search METHIONINE+FREE+DIET
9 POLYHEMOGLOBIN TYROSINASE 3 100% 1% 3 Search POLYHEMOGLOBIN+TYROSINASE Search POLYHEMOGLOBIN+TYROSINASE
10 CENU 2 67% 1% 2 Search CENU Search CENU

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 RECOMBINANT METHIONINASE 96 93% 10% 37
2 METABOLIC DEFECT 44 85% 6% 23
3 GAMMA MERCAPTOMETHANE LYASE 25 71% 6% 20
4 SERUM METHIONINE 20 100% 3% 9
5 MERCAPTOMETHANE LYASE 18 83% 3% 10
6 VIRUS 40 TRANSFORMED HUMAN 11 100% 2% 6
7 MALIGNANT RAT 6 80% 1% 4
8 TRIFLUOROMETHIONINE 5 60% 2% 6
9 METHIONINASE GENE THERAPY 4 75% 1% 3
10 BRAIN TUMOR XENOGRAFTS 4 28% 3% 11

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Development of recombinant methioninase to target the general cancer-specific metabolic defect of methionine dependence: a 40-year odyssey 2015 1 43 91%
Methionine dependency and cancer treatment 2003 66 88 65%
A review of methionine dependency and the role of methionine restriction in cancer growth control and life-span extension 2012 30 103 34%
Methionine dependency of cancer cells: a new therapeutic approach? 2008 6 58 81%
Microbial l-methioninase: production, molecular characterization, and therapeutic applications 2010 11 103 46%
Methionine Gamma-Lyase: The Unique Reaction Mechanism, Physiological Roles, and Therapeutic Applications Against Infectious Diseases and Cancers 2009 12 75 49%
Targeting methionine auxotrophy in cancer: discovery & exploration 2012 5 34 56%
L-METHIONINE GAMMA-LYASE FROM PSEUDOMONAS-PUTIDA AND AEROMONAS 1987 45 3 100%
Structural and functional analysis of the antitumor enzyme L-methionine gamma-lyase 2007 0 16 81%
SELENOCYSTEINE 1987 28 3 100%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ.
in class
1 MED SERV 111H 3 50% 1.1% 4
2 KIDSCAN CHILDRENS CANC 2 67% 0.6% 2
3 BIOSTAT PUBL HLTH UNIT 1 100% 0.6% 2
4 HOTEL DIEU POLYCLIN 1 50% 0.6% 2
5 ONCOL HEMATOL SECT 1 50% 0.6% 2
6 PHARMACEUT SCIPHARMACOL TOXICOL PROG 1 100% 0.6% 2
7 INFUS 1 25% 0.8% 3
8 KASER EL AINI HOSP 1 50% 0.3% 1
9 MOL INFORMAT DESIGN 1 50% 0.3% 1
10 QILO HOSP 1 50% 0.3% 1

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000203063 METHYLTHIOADENOSINE PHOSPHORYLASE//MTAP//L ALANOSINE
2 0.0000122405 ARGININE DEIMINASE//ARGININE DEPRIVATION//ADI PEG20
3 0.0000086638 SULFUR REGULATION//HOMOCYSTEINE SYNTHASE//CYS3
4 0.0000075946 TYROSINE PHENOL LYASE//TRYPTOPHANASE//TRYPTOPHAN INDOLE LYASE
5 0.0000066734 ASPARTATE AMINOTRANSFERASE//AROMATIC AMINO ACID AMINOTRANSFERASE//PYRIDOXAL 5 PHOSPHATE
6 0.0000066249 HALITOSIS//ORAL MALODOUR//ORAL MALODOR
7 0.0000059489 METHIONINE ADENOSYLTRANSFERASE//S ADENOSYLMETHIONINE//GLYCINE N METHYLTRANSFERASE
8 0.0000059473 CYSTEAMINYLPHENOL//HYDROXYANISOLE//ANTIMELANOMA
9 0.0000058842 HOMOCYSTEINE THIOLACTONE//PROTEIN N HOMOCYSTEINYLATION//DIETARY HYPERHOMOCYSTEINEMIA
10 0.0000058367 BENZOYLATED DEAE CELLULOSE CHROMATOGRAPHY//POLYADENOSINE DIPHOSPHATE RIBOSE//N NITROSO N ETHYLUREA