Class information for:
Level 1: EXON SKIPPING//DMD GENET THER Y GRP//MC LOCKWOOD MUSCULAR DYSTROPHY

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
18026 508 47.9 90%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
569 13650 DYSTROPHIN//DUCHENNE MUSCULAR DYSTROPHY//MYOTONIC DYSTROPHY

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 EXON SKIPPING Author keyword 21 23% 16% 80
2 DMD GENET THER Y GRP Address 15 88% 1% 7
3 MC LOCKWOOD MUSCULAR DYSTROPHY Address 14 51% 4% 19
4 EXPT MOL MED GRP Address 11 78% 1% 7
5 NEUROMUSCULAR ALS Address 10 50% 3% 14
6 PHOSPHORODIAMIDATE MORPHOLINO OLIGOMER Author keyword 5 60% 1% 6
7 PPMO Author keyword 5 54% 1% 7
8 MORPHOLINO OLIGOMER Author keyword 4 50% 1% 6
9 PHOSPHORODIAMIDATE MORPHOLINO OLIGOMERS Author keyword 4 75% 1% 3
10 SPLICE SWITCHING Author keyword 4 56% 1% 5

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 EXON SKIPPING 21 23% 16% 80 Search EXON+SKIPPING Search EXON+SKIPPING
2 PHOSPHORODIAMIDATE MORPHOLINO OLIGOMER 5 60% 1% 6 Search PHOSPHORODIAMIDATE+MORPHOLINO+OLIGOMER Search PHOSPHORODIAMIDATE+MORPHOLINO+OLIGOMER
3 PPMO 5 54% 1% 7 Search PPMO Search PPMO
4 MORPHOLINO OLIGOMER 4 50% 1% 6 Search MORPHOLINO+OLIGOMER Search MORPHOLINO+OLIGOMER
5 PHOSPHORODIAMIDATE MORPHOLINO OLIGOMERS 4 75% 1% 3 Search PHOSPHORODIAMIDATE+MORPHOLINO+OLIGOMERS Search PHOSPHORODIAMIDATE+MORPHOLINO+OLIGOMERS
6 SPLICE SWITCHING 4 56% 1% 5 Search SPLICE+SWITCHING Search SPLICE+SWITCHING
7 VIVO MORPHOLINO 2 44% 1% 4 Search VIVO+MORPHOLINO Search VIVO+MORPHOLINO
8 EXON SKIPPING THERAPY 2 67% 0% 2 Search EXON+SKIPPING+THERAPY Search EXON+SKIPPING+THERAPY
9 GENETIC THERAPIES 2 67% 0% 2 Search GENETIC+THERAPIES Search GENETIC+THERAPIES
10 MORPHOLINE NUCLEOSIDES 2 67% 0% 2 Search MORPHOLINE+NUCLEOSIDES Search MORPHOLINE+NUCLEOSIDES

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 MORPHOLINO OLIGOMER 17 63% 3% 17
2 2 O METHYL PHOSPHOROTHIOATE 15 88% 1% 7
3 MORPHOLINO OLIGOMER TREATMENT 13 80% 2% 8
4 PRO051 12 59% 3% 13
5 ANTISENSE OLIGOMERS 12 38% 5% 24
6 SPLICING ENHANCER SEQUENCE 11 100% 1% 6
7 MORPHOLINO 9 33% 5% 23
8 PHOSPHORODIAMIDATE MORPHOLINO OLIGOMERS 8 70% 1% 7
9 PEPTIDE CONJUGATED MORPHOLINO 8 100% 1% 5
10 SYSTEMIC DELIVERY 7 10% 14% 69

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
RNA therapeutics: beyond RNA interference and antisense oligonucleotides 2012 218 91 37%
Clinical Trials Using Antisense Oligonucleotides in Duchenne Muscular Dystrophy 2013 35 78 65%
Morpholinos and their peptide conjugates: Therapeutic promise and challenge for Duchenne muscular dystrophy 2010 56 33 61%
Theoretic Applicability of Antisense-Mediated Exon Skipping for Duchenne Muscular Dystrophy Mutations 2009 115 32 59%
A Chemical View of Oligonucleotides for Exon Skipping and Related Drug Applications 2014 9 79 52%
Antisense-mediated modulation of splicing Therapeutic implications for duchenne muscular dystrophy 2010 23 77 77%
The emperor's new dystrophin: finding sense in the noise 2015 1 106 46%
New developments in the use of gene therapy to treat Duchenne muscular dystrophy 2014 13 167 31%
The Status of Exon Skipping as a Therapeutic Approach to Duchenne Muscular Dystrophy 2011 36 45 71%
Skipping Multiple Exons of Dystrophin Transcripts Using Cocktail Antisense Oligonucleotides 2014 4 101 57%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 DMD GENET THER Y GRP 15 88% 1.4% 7
2 MC LOCKWOOD MUSCULAR DYSTROPHY 14 51% 3.7% 19
3 EXPT MOL MED GRP 11 78% 1.4% 7
4 NEUROMUSCULAR ALS 10 50% 2.8% 14
5 NEUROMUSCULAR NEUROL DISORDERS 3 10% 6.3% 32
6 BIOTHER IES MALAD NEUROMUSCULAI UNITE MIXTE U 3 100% 0.6% 3
7 FRIENDS GARRETT CUMMING MUSCULAR DYSTROPHY 3 100% 0.6% 3
8 NEUROMUSCULAR AMYOTROPH LATERAL SCLEROSIS 3 100% 0.6% 3
9 TIANJIN OXFORD JOINT GENE THER Y 2 67% 0.4% 2
10 UPMC UM76 2 67% 0.4% 2

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000208010 MDX MICE//DUCHENNE MUSCULAR DYSTROPHY//MDX
2 0.0000201415 DYSTROPHIN//BECKER MUSCULAR DYSTROPHY//DUCHENNE MUSCULAR DYSTROPHY
3 0.0000147088 SINGLE STRANDED OLIGONUCLEOTIDE//GENE REPAIR//SINGLE STRANDED OLIGONUCLEOTIDES
4 0.0000127691 ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT//ANTISENSE RESEARCH AND DEVELOPMENT//ANTISENSE
5 0.0000125674 DUCHENNE MUSCULAR DYSTROPHY//NORTH STAR AMBULATORY ASSESSMENT//REG HABILITAT
6 0.0000116196 SYNTHET BIOORGAN CHEM//NUCLE ACID//NUCL ACID
7 0.0000104709 CELL PENETRATING PEPTIDE//CELL PENETRATING PEPTIDES//PROTEIN TRANSDUCTION DOMAINS
8 0.0000103029 PEPTIDE NUCLEIC ACIDS//PEPTIDE NUCLEIC ACID//PNA
9 0.0000081952 OLIGONUCLEOTIDE PEPTIDE CONJUGATE//PEPTIDE OLIGONUCLEOTIDE CONJUGATE//OLIGONUCLEOTIDE PEPTIDE CONJUGATES
10 0.0000072084 SR PROTEINS//SR PROTEIN//ALTERNATIVE SPLICING