Class information for:
Level 1: XCT//SYSTEM XC//OXIDATIVE GLUTAMATE TOXICITY

Basic class information

ID Publications Average number
of references
Avg. shr. active
ref. in WoS
17953 511 44.3 83%



Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)



ID, lev.
above
Publications Label for level above
1547 6824 GLUTAMATE TRANSPORTER//CYSTINURIA//GLT 1

Terms with highest relevance score



Rank Term Type of term Relevance score
(tfidf)
Class's shr.
of term's tot.
occurrences
Shr. of publ.
in class containing
term
Num. of
publ. in
class
1 XCT Author keyword 23 49% 7% 34
2 SYSTEM XC Author keyword 21 52% 6% 29
3 OXIDATIVE GLUTAMATE TOXICITY Author keyword 15 82% 2% 9
4 SLC7A11 Author keyword 8 75% 1% 6
5 FOOD PL LIFE SCI Address 6 53% 2% 8
6 CYSTINE TRANSPORT Author keyword 4 47% 1% 7
7 CYSTINE TRANSPORTER Author keyword 4 56% 1% 5
8 ERASTIN Author keyword 3 100% 1% 3
9 XCT SLC7A11 Author keyword 3 100% 1% 3
10 HT22 Author keyword 3 26% 2% 11

Web of Science journal categories

Author Key Words



Rank Web of Science journal category Relevance score
(tfidf)
Class's shr.
of term's tot.
occurrences
Shr. of publ.
in class containing
term
Num. of
publ. in
class
LCSH search Wikipedia search
1 XCT 23 49% 7% 34 Search XCT Search XCT
2 SYSTEM XC 21 52% 6% 29 Search SYSTEM+XC Search SYSTEM+XC
3 OXIDATIVE GLUTAMATE TOXICITY 15 82% 2% 9 Search OXIDATIVE+GLUTAMATE+TOXICITY Search OXIDATIVE+GLUTAMATE+TOXICITY
4 SLC7A11 8 75% 1% 6 Search SLC7A11 Search SLC7A11
5 CYSTINE TRANSPORT 4 47% 1% 7 Search CYSTINE+TRANSPORT Search CYSTINE+TRANSPORT
6 CYSTINE TRANSPORTER 4 56% 1% 5 Search CYSTINE+TRANSPORTER Search CYSTINE+TRANSPORTER
7 ERASTIN 3 100% 1% 3 Search ERASTIN Search ERASTIN
8 XCT SLC7A11 3 100% 1% 3 Search XCT+SLC7A11 Search XCT+SLC7A11
9 HT22 3 26% 2% 11 Search HT22 Search HT22
10 CYSTINE GLUTAMATE ANTIPORTER 3 35% 1% 7 Search CYSTINE+GLUTAMATE+ANTIPORTER Search CYSTINE+GLUTAMATE+ANTIPORTER

Key Words Plus



Rank Web of Science journal category Relevance score
(tfidf)
Class's shr.
of term's tot.
occurrences
Shr. of publ.
in class containing
term
Num. of
publ. in
class
1 SYSTEM XC 21 47% 6% 33
2 CYSTINE GLUTAMATE TRANSPORTER 17 100% 2% 8
3 CYSTINE UPTAKE 16 40% 6% 32
4 XCT 11 100% 1% 6
5 CYSTINE GLUTAMATE ANTIPORTER 10 40% 4% 20
6 GLUTAMIC ACID UPTAKE 9 83% 1% 5
7 CYSTINE TRANSPORT ACTIVITY 7 48% 2% 11
8 LYMPHOMA GROWTH 7 67% 1% 6
9 CYSTINE GLUTAMATE EXCHANGE TRANSPORTER 6 38% 3% 13
10 HUMAN CYSTINE GLUTAMATE TRANSPORTER 6 71% 1% 5

Journals

Reviews



Title Publ. year Cit. Active references % act. ref.
to same field
The Cystine/Glutamate Antiporter System x(c)(-) in Health and Disease: From Molecular Mechanisms to Novel Therapeutic Opportunities 2013 30 286 35%
The oxidative stress-inducible cystine/glutamate antiporter, system x(c)(-): cystine supplier and beyond 2012 55 110 51%
The x(c)(-) cystine/glutamate antiporter: A potential target for therapy of cancer and other diseases 2008 104 137 45%
Redox status in mammalian cells and stem cells during culture in vitro: Critical roles of Nrf2 and cystine transporter activity in the maintenance of redox balance 2014 8 57 39%
The role of iron and reactive oxygen species in cell death 2014 52 100 7%
System xc- cystine/glutamate antiporter: an update on molecular pharmacology and roles within the CNS 2012 34 128 36%
Regulation of xCT expression and system x(c)(-) function in neuronal cells 2012 16 73 47%
A neurocentric perspective on glioma invasion 2014 22 104 10%
The transsulfuration pathway: a source of cysteine for glutathione in astrocytes 2012 13 36 36%
Glutamate transporters in the biology of malignant gliomas 2014 5 168 24%

Address terms



Rank Address term Relevance score
(tfidf)
Class's shr.
of term's tot.
occurrences
Shr. of publ.
in class containing
term
Num. of
publ. in
class
1 FOOD PL LIFE SCI 6 53% 1.6% 8
2 EA4666 3 42% 1.0% 5
3 CELLULAR BIOL ANAT OPHTHALMOL 2 67% 0.4% 2
4 GLIAL BIOL MED 2 13% 2.3% 12
5 FUNCT GENOM BIOTECHNOL 1 50% 0.4% 2
6 CBH 1 40% 0.4% 2
7 BEAUFOUR IPSEN 1 50% 0.2% 1
8 CIVITAN INT 545 1 50% 0.2% 1
9 CNRS URA 1829 1 50% 0.2% 1
10 ERATO GAS BIOL PROJECT 1 50% 0.2% 1

Related classes at same level (level 1)



Rank Relatedness score Related classes
1 0.0000219191 GRM1//PREFERENTIAL LOCALIZATION//GLUTAMATE SIGNALING
2 0.0000209251 BIOMOL INTERACT BREMEN//BIOL CHEM 2//YANGCHUN KU
3 0.0000177505 BOVINE LYMPHOCYTE//LYT2//S METHYLTHIO CYSTEINE
4 0.0000141198 GLUTAMATE PYRUVATE TRANSAMINASE GPT//BLOOD GLUTAMATE SCAVENGING//GLUTAMATE OXALOACETATE TRANSAMINASE GOT
5 0.0000126546 GLUTAMATE TRANSPORTER//GLT 1//EAAT2
6 0.0000097251 DELAYED CALCIUM DEREGULATION//RETINAL CELLS//APTRA
7 0.0000094814 GLUTAMATE CYSTEINE LIGASE//GLUTATHIONE SYNTHETASE DEFICIENCY//GAMMA GLUTAMYLCYSTEINE SYNTHETASE
8 0.0000093256 CLIN BIOMARKERS//MITOCHONDRIAL APOPTOSIS SIGNALING//INTESTINAL OXIDATIVE STRESS
9 0.0000085617 CYSTINURIA//LYSINURIC PROTEIN INTOLERANCE//LAT1
10 0.0000079818 FISETIN//IBDML UMR 6216//3 4 5 TRIHYDROXYCINNAMIC ACID