Class information for:
Level 1: PTP1B//PROTEIN TYROSINE PHOSPHATASE//PROTEIN TYROSINE PHOSPHATASE 1B

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
1787 2415 47.5 91%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
2255 4236 PTP1B//PROTEIN TYROSINE PHOSPHATASE//PRL 3

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 PTP1B Author keyword 133 58% 6% 152
2 PROTEIN TYROSINE PHOSPHATASE Author keyword 104 32% 11% 269
3 PROTEIN TYROSINE PHOSPHATASE 1B Author keyword 56 49% 3% 83
4 PTPIP51 Author keyword 45 94% 1% 16
5 TCPTP Author keyword 41 85% 1% 22
6 PROTEIN TYROSINE PHOSPHATASES Author keyword 37 39% 3% 74
7 RECEPTOR PROTEIN TYROSINE PHOSPHATASE Author keyword 28 64% 1% 28
8 PTP1B INHIBITORS Author keyword 25 73% 1% 19
9 PTP1B INHIBITOR Author keyword 21 61% 1% 23
10 TYROSINE PHOSPHATASE Author keyword 21 24% 3% 75

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 PTP1B 133 58% 6% 152 Search PTP1B Search PTP1B
2 PROTEIN TYROSINE PHOSPHATASE 104 32% 11% 269 Search PROTEIN+TYROSINE+PHOSPHATASE Search PROTEIN+TYROSINE+PHOSPHATASE
3 PROTEIN TYROSINE PHOSPHATASE 1B 56 49% 3% 83 Search PROTEIN+TYROSINE+PHOSPHATASE+1B Search PROTEIN+TYROSINE+PHOSPHATASE+1B
4 PTPIP51 45 94% 1% 16 Search PTPIP51 Search PTPIP51
5 TCPTP 41 85% 1% 22 Search TCPTP Search TCPTP
6 PROTEIN TYROSINE PHOSPHATASES 37 39% 3% 74 Search PROTEIN+TYROSINE+PHOSPHATASES Search PROTEIN+TYROSINE+PHOSPHATASES
7 RECEPTOR PROTEIN TYROSINE PHOSPHATASE 28 64% 1% 28 Search RECEPTOR+PROTEIN+TYROSINE+PHOSPHATASE Search RECEPTOR+PROTEIN+TYROSINE+PHOSPHATASE
8 PTP1B INHIBITORS 25 73% 1% 19 Search PTP1B+INHIBITORS Search PTP1B+INHIBITORS
9 PTP1B INHIBITOR 21 61% 1% 23 Search PTP1B+INHIBITOR Search PTP1B+INHIBITOR
10 TYROSINE PHOSPHATASE 21 24% 3% 75 Search TYROSINE+PHOSPHATASE Search TYROSINE+PHOSPHATASE

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 PTP1B 105 62% 5% 109
2 1B INHIBITORS 87 88% 2% 42
3 1B 83 33% 9% 208
4 CRYP ALPHA 81 96% 1% 25
5 PTP 1B INHIBITORS 79 94% 1% 29
6 SUBSTRATE TRAPPING MUTANTS 73 89% 1% 33
7 DEP 1 70 89% 1% 32
8 NERVOUS SYSTEM AXONS 62 92% 1% 24
9 LAR 51 44% 4% 87
10 PTP1B INHIBITORS 48 60% 2% 52

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
PTP1B as a drug target: recent developments in PTP1B inhibitor discovery 2007 238 69 77%
Inside the human cancer tyrosine phosphatome 2011 133 182 42%
PTP1B and TCPTP - nonredundant phosphatases in insulin signaling and glucose homeostasis 2013 33 132 66%
Protein tyrosine phosphatases: from genes, to function, to disease 2006 618 126 33%
Protein tyrosine phosphatases - from housekeeping enzymes to master regulators of signal transduction 2013 55 219 33%
Small molecule tools for functional interrogation of protein tyrosine phosphatases 2013 33 125 50%
PTP1B: a double agent in metabolism and oncogenesis 2010 74 85 73%
Novel protein tyrosine phosphatase 1B inhibitors: interaction requirements for improved intracellular efficacy in type 2 diabetes mellitus and obesity control 2011 46 42 76%
Protein-tyrosine phosphatases and cancer 2006 283 154 50%
PTP1B: From the sidelines to the front lines! 2003 203 69 87%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 EDMOND H FI ER SIGNAL TRANSDUCT 5 28% 0.6% 15
2 MEDCHEM 1 5 63% 0.2% 5
3 47R 4 67% 0.2% 4
4 MED C6 4 67% 0.2% 4
5 MEDDORRANCE H HAMILTON S 2 32% 0.2% 6
6 MCGILL GOODMAN CANC 2 67% 0.1% 2
7 MEDCHEM 2 2 67% 0.1% 2
8 PROGRAM MOL VET BIOSCI 2 67% 0.1% 2
9 MEDCHEM 4 2 40% 0.2% 4
10 CHEM GENOM CORE IL 2 29% 0.2% 6

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000174948 ACP1//PHOSPHOTYROSINE PROTEIN PHOSPHATASE//LMW PTP
2 0.0000168338 SHP 2//SHP 1//GAB1
3 0.0000130127 PRL 3//PHOSPHATASE OF REGENERATING LIVER 3//PRL 1
4 0.0000129438 MKP 1//MAP KINASE PHOSPHATASE//DUAL SPECIFICITY PHOSPHATASE
5 0.0000092554 SULFENIC ACID//HSP33//CYSTEINE OXIDATION
6 0.0000092306 STRIATAL ENRICHED PROTEIN TYROSINE PHOSPHATASE//FYN TYROSINE KINASE//PROGRAMME BRAIN BEHAV
7 0.0000091706 CD45//CD45 ISOFORMS//P56LCK
8 0.0000064475 CDC25B//CDC25A//AUTOSCHIZIS
9 0.0000051162 BACTERIAL PROTEIN PHOSPHORYLATION//BY KINASE//BIOL CHEM PROT
10 0.0000047743 DIFLUOROMETHYLENEPHOSPHONATES//DIFLUOROPHOSPHONATE//PHOSPHATE MIMICS