Class information for:
Level 1: THYMIDYLATE SYNTHASE//THYX//DEOXYTUBULOSINE

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
17500 532 32.9 62%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
1587 6631 FOLATE RECEPTOR//REDUCED FOLATE CARRIER//DIHYDROFOLATE REDUCTASE

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 THYMIDYLATE SYNTHASE Author keyword 12 11% 19% 103
2 THYX Author keyword 6 100% 1% 4
3 DEOXYTUBULOSINE Author keyword 4 75% 1% 3
4 FLUORODEOXYURIDYLATE Author keyword 3 100% 1% 3
5 HUMAN THYMIDYLATE SYNTHASE Author keyword 3 100% 1% 3
6 ANTIFOLATE BINDING Author keyword 2 67% 0% 2
7 BIOCHEM BIOPHYS S960 Address 2 67% 0% 2
8 FOLATE ANALOGUES Author keyword 2 67% 0% 2
9 ONE CARBON UNIT TRANSFER Author keyword 2 26% 1% 5
10 DUMP Author keyword 1 15% 2% 9

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 THYMIDYLATE SYNTHASE 12 11% 19% 103 Search THYMIDYLATE+SYNTHASE Search THYMIDYLATE+SYNTHASE
2 THYX 6 100% 1% 4 Search THYX Search THYX
3 DEOXYTUBULOSINE 4 75% 1% 3 Search DEOXYTUBULOSINE Search DEOXYTUBULOSINE
4 FLUORODEOXYURIDYLATE 3 100% 1% 3 Search FLUORODEOXYURIDYLATE Search FLUORODEOXYURIDYLATE
5 HUMAN THYMIDYLATE SYNTHASE 3 100% 1% 3 Search HUMAN+THYMIDYLATE+SYNTHASE Search HUMAN+THYMIDYLATE+SYNTHASE
6 ANTIFOLATE BINDING 2 67% 0% 2 Search ANTIFOLATE+BINDING Search ANTIFOLATE+BINDING
7 FOLATE ANALOGUES 2 67% 0% 2 Search FOLATE+ANALOGUES Search FOLATE+ANALOGUES
8 ONE CARBON UNIT TRANSFER 2 26% 1% 5 Search ONE+CARBON+UNIT+TRANSFER Search ONE+CARBON+UNIT+TRANSFER
9 DUMP 1 15% 2% 9 Search DUMP Search DUMP
10 2 DEOXYURIDINE 5 MONOPHOSPHATE 1 100% 0% 2 Search 2++DEOXYURIDINE+5++MONOPHOSPHATE Search 2++DEOXYURIDINE+5++MONOPHOSPHATE

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 10 PROPARGYL 5 8 DIDEAZAFOLATE 76 93% 5% 28
2 5 FLUORO 2 DEOXYURIDYLATE 57 62% 11% 59
3 THYX 53 95% 3% 18
4 ASPARAGINE 229 29 88% 3% 14
5 INACTIVE MUTANTS 27 92% 2% 11
6 COMPLEMENTING PROTEIN 25 75% 3% 18
7 5 FLUORODEOXYURIDYLATE 19 80% 2% 12
8 5 10 METHYLENETETRAHYDROFOLATE 17 55% 4% 21
9 SITES ACTIVITY ENZYME 15 88% 1% 7
10 MAMMALIAN TUMOR 12 86% 1% 6

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
THE CATALYTIC MECHANISM AND STRUCTURE OF THYMIDYLATE SYNTHASE 1995 459 116 64%
Thymidyl biosynthesis enzymes as antibiotic targets 2007 11 36 58%
Thymidylate synthase structure, function and implication in drug discovery 2005 43 69 46%
Mechanisms and inhibition of uracil methylating enzymes 2012 2 47 57%
Sequence-based identification of specific drug target regions in the thymidylate synthase enzyme family 2008 3 46 57%
Novel chemical strategies for thymidylate synthase inhibition 2005 35 128 26%
Effects of ligand binding and conformational switching on intracellular stability of human thymidylate synthase 2004 24 49 37%
Thymidylate synthase inhibition: A structure-based rationale for drug design 1998 12 88 41%
5,6-DIHYDROPYRIMIDINE ADDUCTS IN THE REACTIONS AND INTERACTIONS OF PYRIMIDINES WITH PROTEINS 1992 42 33 39%
Uncommon and parallel developmental patterns of thymidylate synthase expression and localization in Trichinella spiralis and Caenorhabditis elegans 2013 0 21 38%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ.
in class
1 BIOCHEM BIOPHYS S960 2 67% 0.4% 2
2 CHAIR COSMETOL 1 100% 0.4% 2
3 RADIAT BIOL BIOCHEM 1 18% 1.1% 6
4 MED PROGRAM MOLEC MED 1 33% 0.4% 2
5 DIPARTIMENTO BIOPATHOL 1 50% 0.2% 1
6 GENOM PHYSIOL MICROBIENNE 1 50% 0.2% 1
7 U451CNRSUMR 7645 1 50% 0.2% 1
8 BURKE S 1 18% 0.6% 3
9 INTER E VALORISAT PLATFORM IV 1 25% 0.4% 2
10 AQUAT MOL BIOL 1 12% 0.8% 4

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000247314 THYMIDYLATE SYNTHASE//DIHYDROPYRIMIDINE DEHYDROGENASE//OROTATE PHOSPHORIBOSYL TRANSFERASE
2 0.0000154789 TETRAHYDROFOLATE COENZYME MODEL//ONE CARBON UNIT TRANSFER//TETRAHYDROFOLATE COENZYME
3 0.0000149250 REDUCED FOLATE CARRIER//FOLYLPOLYGLUTAMATE SYNTHETASE//HEREDITARY FOLATE MALABSORPTION
4 0.0000108676 DIHYDROFOLATE REDUCTASE//HYDROGEN TUNNELING//PROMOTING VIBRATION
5 0.0000085629 BV ARAU//5 ETHYL 2 DEOXYURIDINE//BCNA
6 0.0000080096 SERINE HYDROXYMETHYLTRANSFERASE//THREONINE ALDOLASE//BIOCATALYT CHEM
7 0.0000079050 HPPK//DIHYDROPTEROATE SYNTHASE//PYROPHOSPHOKINASE
8 0.0000064799 BIOCHEMICAL MODULATION//LEUCOVORIN//FOLINIC ACID
9 0.0000044729 ACETYLENIC AMINO ACID//MULTISUBSTRATE INHIBITOR//COENZYME MODEL
10 0.0000042447 PHENANTHROINDOLIZIDINE ALKALOID//PHENANTHROINDOLIZIDINE//TYLOPHORINE