Class information for:
Level 1: HIRUDIN//FACTOR XA//THROMBIN INHIBITOR

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
1626 2481 36.4 72%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
261 18876 PROTEIN C//ACTIVATED PROTEIN C//TISSUE FACTOR

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 HIRUDIN Author keyword 78 36% 7% 174
2 FACTOR XA Author keyword 30 23% 5% 114
3 THROMBIN INHIBITOR Author keyword 30 32% 3% 77
4 DX 9065A Author keyword 25 75% 1% 18
5 FACTOR XA INHIBITOR Author keyword 24 31% 3% 65
6 THROMBIN INHIBITORS Author keyword 22 31% 2% 61
7 RECOMBINANT HIRUDIN Author keyword 20 42% 1% 37
8 HIRULOG Author keyword 12 53% 1% 16
9 YM466 Author keyword 12 86% 0% 6
10 FACTOR XA INHIBITORS Author keyword 11 25% 2% 39

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 HIRUDIN 78 36% 7% 174 Search HIRUDIN Search HIRUDIN
2 FACTOR XA 30 23% 5% 114 Search FACTOR+XA Search FACTOR+XA
3 THROMBIN INHIBITOR 30 32% 3% 77 Search THROMBIN+INHIBITOR Search THROMBIN+INHIBITOR
4 DX 9065A 25 75% 1% 18 Search DX+9065A Search DX+9065A
5 FACTOR XA INHIBITOR 24 31% 3% 65 Search FACTOR+XA+INHIBITOR Search FACTOR+XA+INHIBITOR
6 THROMBIN INHIBITORS 22 31% 2% 61 Search THROMBIN+INHIBITORS Search THROMBIN+INHIBITORS
7 RECOMBINANT HIRUDIN 20 42% 1% 37 Search RECOMBINANT+HIRUDIN Search RECOMBINANT+HIRUDIN
8 HIRULOG 12 53% 1% 16 Search HIRULOG Search HIRULOG
9 YM466 12 86% 0% 6 Search YM466 Search YM466
10 FACTOR XA INHIBITORS 11 25% 2% 39 Search FACTOR+XA+INHIBITORS Search FACTOR+XA+INHIBITORS

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 HUMAN ALPHA THROMBIN 264 53% 14% 350
2 COAGULATION FACTOR XA 114 43% 8% 203
3 RECOMBINANT HIRUDIN 96 31% 10% 256
4 HIRUDIN 78 33% 8% 194
5 PRO ARG CHLOROMETHYLKETONE 78 54% 4% 99
6 DX 9065A 77 79% 2% 49
7 YM 60828 69 96% 1% 22
8 NA BINDING 54 71% 2% 44
9 1 2 DIBENZAMIDOBENZENE INHIBITORS 48 100% 1% 17
10 HEPARIN ANTITHROMBIN 42 48% 3% 64

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Oral, Direct Thrombin and Factor Xa Inhibitors: The Replacement for Warfarin, Leeches, and Pig Intestines? 2011 28 63 65%
Synthetic inhibitors of thrombin and factor Xa: From bench to bedside 1999 108 245 78%
Molecular dissection of Na+ binding to thrombin 2004 103 98 54%
Small, noncovalent serine protease inhibitors 1999 85 82 85%
Thrombin 2008 78 220 49%
Progress in the development of synthetic thrombin inhibitors as new orally active anticoagulants 2004 51 159 76%
The race to an orally active Factor Xa inhibitor: Recent advances 2004 47 44 80%
Factor Xa inhibitors: Recent advances in anticoagulant agents 2000 57 17 100%
Thrombin inhibitor design 1998 86 70 83%
An ensemble view of thrombin allostery 2012 19 43 65%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 ZENTRUM VASKULARE BIOL MED 8 56% 0.4% 10
2 CARDIOVASC THER EUT SECT 3 100% 0.1% 3
3 NEW LEADS GENERAT 3 100% 0.1% 3
4 UNIT PHARMACOL HAEMOSTASEOL 3 40% 0.2% 6
5 EAGLEVIEW CORP 3 50% 0.2% 4
6 THROMBOSIS UNITCAMBRIDGE MED 3 60% 0.1% 3
7 MOL DESIGN ERS 2 24% 0.4% 9
8 THROMBOSIS HAEMATOL 2 67% 0.1% 2
9 THROMBOSIS HAEMATOL SECT 2 67% 0.1% 2
10 VASC CARDIAC DIS SECT 2 67% 0.1% 2

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000120190 FACTOR V DEFICIENCY//FACTOR VA//FACTOR V
2 0.0000111722 HAEMENTERIA GHILIANII//MEDICINAL LEECH//LEECHES
3 0.0000100182 ECOTIN//STREPTOMYCES ERYTHRAEUS//BOVINE BETA TRYPSIN
4 0.0000096598 RIVAROXABAN//DABIGATRAN//APIXABAN
5 0.0000073589 HEPARIN INDUCED THROMBOCYTOPENIA//ARGATROBAN//LEPIRUDIN
6 0.0000067760 THROMBOMODULIN//SOLUBLE THROMBOMODULIN//PLASMA THROMBOMODULIN
7 0.0000065260 HEPARIN COFACTOR II//ANTITHROMBIN//ANTITHROMBIN DEFICIENCY
8 0.0000064740 ALLIED MED SCI SUMA KU//MED FUKUSHIMA KU//TARUMI KU
9 0.0000056611 EPTIFIBATIDE//TIROFIBAN//ABCIXIMAB
10 0.0000054731 PROTEASE ACTIVATED RECEPTOR//PROTEASE ACTIVATED RECEPTORS//THROMBIN RECEPTOR