Class information for:
Level 1: MICROSATELLITE INSTABILITY//LYNCH SYNDROME//HNPCC

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
160 4045 37.5 90%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
580 13536 MICROSATELLITE INSTABILITY//LYNCH SYNDROME//HNPCC

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 MICROSATELLITE INSTABILITY Author keyword 661 51% 23% 937
2 LYNCH SYNDROME Author keyword 653 72% 13% 517
3 HNPCC Author keyword 471 70% 10% 393
4 HEREDITARY NONPOLYPOSIS COLORECTAL CANCER Author keyword 207 69% 4% 179
5 MLH1 Author keyword 160 55% 5% 200
6 HMLH1 Author keyword 153 61% 4% 164
7 HEREDITARY NON POLYPOSIS COLORECTAL CANCER Author keyword 146 76% 3% 103
8 HMSH2 Author keyword 145 68% 3% 126
9 MSH2 Author keyword 121 53% 4% 159
10 MISMATCH REPAIR Author keyword 87 29% 6% 254

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 MICROSATELLITE INSTABILITY 661 51% 23% 937 Search MICROSATELLITE+INSTABILITY Search MICROSATELLITE+INSTABILITY
2 LYNCH SYNDROME 653 72% 13% 517 Search LYNCH+SYNDROME Search LYNCH+SYNDROME
3 HNPCC 471 70% 10% 393 Search HNPCC Search HNPCC
4 HEREDITARY NONPOLYPOSIS COLORECTAL CANCER 207 69% 4% 179 Search HEREDITARY+NONPOLYPOSIS+COLORECTAL+CANCER Search HEREDITARY+NONPOLYPOSIS+COLORECTAL+CANCER
5 MLH1 160 55% 5% 200 Search MLH1 Search MLH1
6 HMLH1 153 61% 4% 164 Search HMLH1 Search HMLH1
7 HEREDITARY NON POLYPOSIS COLORECTAL CANCER 146 76% 3% 103 Search HEREDITARY+NON+POLYPOSIS+COLORECTAL+CANCER Search HEREDITARY+NON+POLYPOSIS+COLORECTAL+CANCER
8 HMSH2 145 68% 3% 126 Search HMSH2 Search HMSH2
9 MSH2 121 53% 4% 159 Search MSH2 Search MSH2
10 MISMATCH REPAIR 87 29% 6% 254 Search MISMATCH+REPAIR Search MISMATCH+REPAIR

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of publ.
in class
1 NONPOLYPOSIS COLORECTAL CANCER 759 47% 30% 1202
2 HNPCC 737 77% 12% 497
3 HMLH1 482 67% 11% 429
4 LYNCH SYNDROME 449 53% 15% 593
5 MISMATCH REPAIR GENES 353 70% 7% 296
6 HMSH2 352 77% 6% 239
7 MICROSATELLITE INSTABILITY 334 21% 35% 1411
8 REVISED BETHESDA GUIDELINES 262 82% 4% 155
9 NONPOLYPOSIS COLON CANCER 261 50% 9% 376
10 BETHESDA GUIDELINES 248 79% 4% 161

Journals


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 FAMILIAL CANCER 38 21% 4% 160
2 HEREDITARY CANCER IN CLINICAL PRACTICE 5 16% 1% 26

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Revised guidelines for the clinical management of Lynch syndrome (HNPCC): recommendations by a group of European experts 2013 83 109 72%
Guidelines for the clinical management of Lynch syndrome (hereditary non-polyposis cancer) 2007 265 52 94%
Genomic medicine - Hereditary colorectal cancer 2003 865 77 57%
Systematic review of microsatellite instability and colorectal cancer prognosis 2005 630 79 54%
Review of the Lynch syndrome: history, molecular genetics, screening, differential diagnosis, and medicolegal ramifications 2009 213 118 75%
Recommendations for the care of individuals with an inherited predisposition to Lynch syndrome - A systematic review 2006 274 89 84%
Correlation of tumour BRAF mutations and MLH1 methylation with germline mismatch repair (MMR) gene mutation status: a literature review assessing utility of tumour features for MMR variant classification 2012 49 47 85%
Guidelines on Genetic Evaluation and Management of Lynch Syndrome: A Consensus Statement by the US Multi-Society Task Force on Colorectal Cancere 2014 14 136 85%
Lessons from hereditary colorectal cancer 1996 3252 87 28%
Milestones of Lynch syndrome: 1895-2015 2015 2 177 65%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 DANISH HNPCC REGISTER 28 81% 0.4% 17
2 NETHERLANDS FDN DETECT HEREDITARY TUMOURS 20 59% 0.5% 22
3 ONCOL SPERIMENTALE 1 18 83% 0.2% 10
4 HEREDITARY GASTROINTESTINAL CANC REGISTRY 13 71% 0.2% 10
5 HNPCC REGISTER 11 65% 0.3% 11
6 NEW ZEALAND FAMILIAL GASTROINTESTINAL CANC REGIST 11 69% 0.2% 9
7 FAMILIAL GASTROINTESTINAL CANC REGISTRY 8 43% 0.4% 15
8 HEREDITARY GASTROINTESTINAL CANC GENET DIAG 8 100% 0.1% 5
9 U434 8 21% 0.8% 33
10 COLORECTAL CANC PREVENT PROGRAM 6 80% 0.1% 4

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000173852 MUTS//MISMATCH REPAIR//DNA MISMATCH REPAIR
2 0.0000130245 SERRATED ADENOMA//SESSILE SERRATED ADENOMA//TRADITIONAL SERRATED ADENOMA
3 0.0000117514 FAMILIAL ADENOMATOUS POLYPOSIS//APC GENE//MUTYH
4 0.0000104516 INTER SIMPLE SEQUENCE REPEAT PCR//BIOPHYS CYTOMETRY//HOSP UNIV SALAMANCA IBSAL
5 0.0000078695 PROXIMAL SHIFT//SUBSITE//ANATOMIC SUBSITE
6 0.0000071044 SEBACEOUS CARCINOMA//MUIR TORRE SYNDROME//SEBACEOUS ADENOMA
7 0.0000069321 ASIAN CANCER CONTROL//BUR HLTH TECHNOL RD PLANNING BUDGET MANAGEMENT//EARLY DETECT PREVENT
8 0.0000056658 HUMAN CYTOGENET TOXICOL GENET//C KI RAS ONCOGENE//JOAO BARROS BARRETO UNIV HOSP
9 0.0000050380 DNA MULTIPLOIDY//DNA PLOIDY//DNA PLOIDY HETEROGENEITY
10 0.0000048395 FLAT ADENOMA//DEPRESSED ADENOMA//POLYPOID GROWTH