Class information for: |
Basic class information |
ID | Publications | Average number of references |
Avg. shr. active ref. in WoS |
---|---|---|---|
15823 | 621 | 38.4 | 74% |
Classes in level above (level 2) |
ID, lev. above |
Publications | Label for level above |
---|---|---|
2357 | 3920 | DUOCARMYCINS//PYRROLOBENZODIAZEPINE//PYRROLE IMIDAZOLE POLYAMIDE |
Terms with highest relevance score |
Rank | Term | Type of term | Relevance score (tfidf) |
Class's shr. of term's tot. occurrences |
Shr. of publ. in class containing term |
Num. of publ. in class |
---|---|---|---|---|---|---|
1 | DUOCARMYCINS | Author keyword | 61 | 88% | 5% | 29 |
2 | CC 1065 | Author keyword | 51 | 83% | 5% | 29 |
3 | DUOCARMYCIN | Author keyword | 48 | 77% | 5% | 33 |
4 | ADOZELESIN | Author keyword | 45 | 94% | 3% | 16 |
5 | BIZELESIN | Author keyword | 34 | 93% | 2% | 13 |
6 | DUOCARMYCIN SA | Author keyword | 20 | 100% | 1% | 9 |
7 | KW 2189 | Author keyword | 14 | 100% | 1% | 7 |
8 | CARZELESIN | Author keyword | 12 | 86% | 1% | 6 |
9 | DUOCARMYCIN A | Author keyword | 6 | 80% | 1% | 4 |
10 | CC 1065 ANTITUMOR ANTIBIOTIC | Author keyword | 3 | 100% | 0% | 3 |
Web of Science journal categories |
Author Key Words |
Rank | Web of Science journal category | Relevance score (tfidf) |
Class's shr. of term's tot. occurrences |
Shr. of publ. in class containing term |
Num. of publ. in class |
LCSH search | Wikipedia search |
---|---|---|---|---|---|---|---|
1 | DUOCARMYCINS | 61 | 88% | 5% | 29 | Search DUOCARMYCINS | Search DUOCARMYCINS |
2 | CC 1065 | 51 | 83% | 5% | 29 | Search CC+1065 | Search CC+1065 |
3 | DUOCARMYCIN | 48 | 77% | 5% | 33 | Search DUOCARMYCIN | Search DUOCARMYCIN |
4 | ADOZELESIN | 45 | 94% | 3% | 16 | Search ADOZELESIN | Search ADOZELESIN |
5 | BIZELESIN | 34 | 93% | 2% | 13 | Search BIZELESIN | Search BIZELESIN |
6 | DUOCARMYCIN SA | 20 | 100% | 1% | 9 | Search DUOCARMYCIN+SA | Search DUOCARMYCIN+SA |
7 | KW 2189 | 14 | 100% | 1% | 7 | Search KW+2189 | Search KW+2189 |
8 | CARZELESIN | 12 | 86% | 1% | 6 | Search CARZELESIN | Search CARZELESIN |
9 | DUOCARMYCIN A | 6 | 80% | 1% | 4 | Search DUOCARMYCIN+A | Search DUOCARMYCIN+A |
10 | CC 1065 ANTITUMOR ANTIBIOTIC | 3 | 100% | 0% | 3 | Search CC+1065+ANTITUMOR+ANTIBIOTIC | Search CC+1065+ANTITUMOR+ANTIBIOTIC |
Key Words Plus |
Rank | Web of Science journal category | Relevance score (tfidf) |
Class's shr. of term's tot. occurrences |
Shr. of publ. in class containing term |
Num. of publ. in class |
---|---|---|---|---|---|
1 | LEFT HAND SUBUNIT | 193 | 89% | 14% | 88 |
2 | NONCOVALENT BINDING SELECTIVITY | 192 | 98% | 8% | 49 |
3 | CC 1065 | 168 | 64% | 26% | 163 |
4 | DNA ALKYLATION PROPERTIES | 157 | 100% | 7% | 42 |
5 | ENHANCED FUNCTIONAL ANALOGS | 131 | 88% | 10% | 61 |
6 | ANTITUMOR ANTIBIOTIC CC 1065 | 108 | 75% | 12% | 77 |
7 | CC 1065 NSC 298223 | 98 | 84% | 9% | 53 |
8 | BENZANNELATED ANALOG | 93 | 100% | 5% | 28 |
9 | NSC 298223 | 91 | 94% | 5% | 32 |
10 | ELECTROPHILE REACTIVITY | 89 | 100% | 4% | 27 |
Journals |
Reviews |
Title | Publ. year | Cit. | Active references | % act. ref. to same field |
---|---|---|---|---|
CC-1065 and the duocarmycins: Understanding their biological function through mechanistic studies | 1996 | 222 | 184 | 91% |
CC-1065 and the duocarmycins: Synthetic studies | 1997 | 177 | 201 | 78% |
Shape-dependent catalysis: Insights into the source of catalysis for the CC-1065 and duocarmycin DNA alkylation reaction | 1999 | 86 | 49 | 98% |
Yatakemycin: total synthesis, DNA alkylation, and biological properties | 2008 | 17 | 20 | 95% |
CC-1065 AND THE DUOCARMYCINS - UNRAVELING THE KEYS TO A NEW CLASS OF NATURALLY DERIVED DNA ALKYLATING-AGENTS | 1995 | 119 | 69 | 90% |
DNA minor groove binders: Back in the groove | 2009 | 33 | 85 | 39% |
THE DUOCARMYCINS - SYNTHETIC AND MECHANISTIC STUDIES | 1995 | 82 | 70 | 97% |
Chemical and Biological Explorations of the Family of CC-1065 and the Duocarmycin Natural Products | 2009 | 11 | 145 | 74% |
Prodrugs for Targeted Tumor Therapies: Recent Developments in ADEPT, GDEPT and PMT | 2011 | 26 | 151 | 27% |
Duocarmycins - Natures prodrugs? | 2002 | 23 | 60 | 80% |
Address terms |
Rank | Address term | Relevance score (tfidf) |
Class's shr. of term's tot. occurrences |
Shr. of publ. in class containing term |
Num. of publ. in class |
---|---|---|---|---|---|
1 | DNA INTERACT GRP | 3 | 60% | 0.5% | 3 |
2 | CANC UK DRUG | 2 | 67% | 0.3% | 2 |
3 | AUCKLAND SOC | 1 | 50% | 0.2% | 1 |
4 | BIOSCI ORGAN | 1 | 50% | 0.2% | 1 |
5 | NEW MOL ENT | 1 | 50% | 0.2% | 1 |
6 | TTPA | 1 | 50% | 0.2% | 1 |
7 | MATH ECON INFORMAT SCI | 0 | 33% | 0.2% | 1 |
8 | ADVANCING MED INNOVAT | 0 | 25% | 0.2% | 1 |
9 | CANC CAMPAIGN DRUG DNA INTERACT GRP | 0 | 25% | 0.2% | 1 |
10 | UPS TAAM CIPA 44 | 0 | 25% | 0.2% | 1 |
Related classes at same level (level 1) |
Rank | Relatedness score | Related classes |
---|---|---|
1 | 0.0000181282 | PYRROLE IMIDAZOLE POLYAMIDE//DISTAMYCIN//MINOR GROOVE BINDERS |
2 | 0.0000158767 | CB1954//ADEPT//ANTIBODY DIRECTED ENZYME PRODRUG THERAPY |
3 | 0.0000111452 | PYRROLOBENZODIAZEPINE//PYRROLOBENZODIAZEPINES//PYRROLO2 1 C1 4BENZODIAZEPINES |
4 | 0.0000107210 | PI CONJUGATED ORGANIC COMPOUND//RIBBON LIKE MOLECULAR ARRANGEMENT//2 AMINOMETHYL 5 HYDROXY 1H INDOLE 3 CARBOXYLIC ACIDS |
5 | 0.0000085016 | IROFULVEN//MGI 114//HMAF |
6 | 0.0000061966 | ANTIBODY DRUG CONJUGATE//ANTIBODY DRUG CONJUGATES//T DM1 |
7 | 0.0000045910 | ANTHROSE//SECT CARBOHYDRATES//VIBRIO CHOLERAE O 1 |
8 | 0.0000044941 | 2 HYDRAZONOPHENYLTHIOACETAMIDES//6 AZAURACILS//1 ARYL 6 AZACYTOSINE |
9 | 0.0000042633 | COUNTING RESIDUES//B3LYP 6 31GD METHOD//CATIONIC SIGMA COMPLEXES |
10 | 0.0000042122 | AZAINDOLES//7 AZAINDOLES//2 ETHYNYLANILINE |