Class information for:
Level 1: METHADONE//EDDP//2 ETHYLIDENE 1 5 DIMETHYL 3 3 DIPHENYLPYRROLIDINE

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
15331 648 33.8 65%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
1638 6431 TRAMADOL//BREAKTHROUGH PAIN//MORPHINE 6 GLUCURONIDE

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 METHADONE Author keyword 32 12% 39% 250
2 EDDP Author keyword 11 50% 2% 16
3 2 ETHYLIDENE 1 5 DIMETHYL 3 3 DIPHENYLPYRROLIDINE Author keyword 8 100% 1% 5
4 EMDP Author keyword 6 80% 1% 4
5 METHADONE ENANTIOMERS Author keyword 6 100% 1% 4
6 S METHADONE Author keyword 4 67% 1% 4
7 CLINICAL OPIOID WITHDRAWAL SCALE Author keyword 3 100% 0% 3
8 R METHADONE Author keyword 3 60% 0% 3
9 LEVOMETHADONE Author keyword 2 44% 1% 4
10 ADDICT FORENS PSYCHIAT Address 2 67% 0% 2

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 METHADONE 32 12% 39% 250 Search METHADONE Search METHADONE
2 EDDP 11 50% 2% 16 Search EDDP Search EDDP
3 2 ETHYLIDENE 1 5 DIMETHYL 3 3 DIPHENYLPYRROLIDINE 8 100% 1% 5 Search 2+ETHYLIDENE+1+5+DIMETHYL+3+3+DIPHENYLPYRROLIDINE Search 2+ETHYLIDENE+1+5+DIMETHYL+3+3+DIPHENYLPYRROLIDINE
4 EMDP 6 80% 1% 4 Search EMDP Search EMDP
5 METHADONE ENANTIOMERS 6 100% 1% 4 Search METHADONE+ENANTIOMERS Search METHADONE+ENANTIOMERS
6 S METHADONE 4 67% 1% 4 Search S+METHADONE Search S+METHADONE
7 CLINICAL OPIOID WITHDRAWAL SCALE 3 100% 0% 3 Search CLINICAL+OPIOID+WITHDRAWAL+SCALE Search CLINICAL+OPIOID+WITHDRAWAL+SCALE
8 R METHADONE 3 60% 0% 3 Search R+METHADONE Search R+METHADONE
9 LEVOMETHADONE 2 44% 1% 4 Search LEVOMETHADONE Search LEVOMETHADONE
10 6 DIMETHYLAMINO 4 4 DIPHENYL 3 HEPTANONE METHADONE 1 100% 0% 2 Search 6+DIMETHYLAMINO+4+4+DIPHENYL+3+HEPTANONE+METHADONE Search 6+DIMETHYLAMINO+4+4+DIPHENYL+3+HEPTANONE+METHADONE

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 R METHADONE 44 85% 4% 23
2 INHIBITOR LOPINAVIR RITONAVIR 32 88% 2% 15
3 S METHADONE 30 79% 3% 19
4 HIGH DOSE METHADONE 20 49% 4% 29
5 DL METHADONE 18 89% 1% 8
6 P4503A CYP3A ACTIVITY 13 80% 1% 8
7 N DEMETHYLATION 11 13% 13% 85
8 RACEMIC METHADONE 9 83% 1% 5
9 URINARY ENANTIOMERS 8 75% 1% 6
10 MMT PATIENTS 8 100% 1% 5

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Methadone Overdose and Cardiac Arrhythmia Potential: Findings From a Review of the Evidence for an American Pain Society and College on Problems of Drug Dependence Clinical Practice Guideline 2014 6 82 37%
Interindividual variability of the clinical pharmacokinetics of methadone - Implications for the treatment of opioid dependence 2002 250 169 56%
A review of pharmacological interactions between HIV or hepatitis C virus medications and opioid agonist therapy: implications and management for clinical practice 2013 9 151 43%
Methadone: To ECG or Not to ECG ... That Is Still the Question 2008 24 34 76%
Impact of ABCB1 and CYP2B6 Genetic Polymorphisms on Methadone Metabolism, Dose and Treatment Response in Patients with Opioid Addiction: A Systematic Review and Meta-Analysis 2014 2 53 43%
Actual and potential drug interactions associated with methadone 2008 38 136 48%
Methadone: a review of drug-drug and pathophysiological interactions 2011 16 181 46%
Methadone-induced mortality in the treatment of chronic pain: Role of QT prolongation 2009 18 58 50%
Interindividual variability of methadone response - Impact of genetic polymorphism 2008 37 141 37%
Methadone: a review of its pharmacokinetic/pharmacodynamic properties 1999 73 37 41%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ.
in class
1 ADDICT FORENS PSYCHIAT 2 67% 0.3% 2
2 UNIT BIOCHEM CLIN PSYCHOPHARMACOL PSYCHIAT 2 67% 0.3% 2
3 UNIT DRUG ADDICT 2 67% 0.3% 2
4 SONG DE BRANCH 2 40% 0.6% 4
5 ST MARTIN 2 36% 0.6% 4
6 UNIT BIOCHEM CLIN PSYCHOPHARMACOL 2 23% 1.1% 7
7 DRUG ABUSE ADDICT 2 20% 1.1% 7
8 PSYCHIAT NEUROSCI PSYCHIAT 1 38% 0.5% 3
9 ADULT ACTG PHARMACOL SUPPORT 1 100% 0.3% 2
10 S BIOCHIM NUTR 1 100% 0.3% 2

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000218946 BUPRENORPHINE//METHADONE//BUPRENORPHINE NALOXONE
2 0.0000147958 OVERDOSE PREVENTION//NON FATAL OVERDOSE//DRUG RELATED DEATHS
3 0.0000120565 BREAKTHROUGH PAIN//OPIOID ROTATION//CANCER PAIN
4 0.0000109919 OPRM1//A118G//OPRM1 GENE
5 0.0000091004 ADDICT URBAN HLTH INITIAT//ADDITIONAL ABUSE//ASSESSMENT TREATMENT ALCOHOL RELATED PATHOL
6 0.0000078016 EFAVIRENZ//CYP2B6//NEVIRAPINE
7 0.0000070919 LOFEXIDINE//NALTREXONE//UNIT EDUC DRUGS ALCOHOL
8 0.0000065738 CO PROXAMOL//DEXTROPROPOXYPHENE//POISONS CENTRES
9 0.0000058005 HAIR ANALYSIS//HAIR TESTING//HAIR
10 0.0000052050 AFFILIATED OBSTET GYNECOL HOSP//MORPHINE 6 DEHYDROGENASE//ANTIOXIDASE