Class information for:
Level 1: SIRT1//SIRTUIN//SIRT3

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
1510 2532 54.2 93%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
2158 4521 SIRT1//SIRTUIN//FOXM1

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 SIRT1 Author keyword 311 47% 20% 494
2 SIRTUIN Author keyword 183 61% 8% 194
3 SIRT3 Author keyword 157 79% 4% 101
4 SIRTUINS Author keyword 153 52% 8% 208
5 SIRT2 Author keyword 106 81% 3% 64
6 SIRT5 Author keyword 65 95% 1% 21
7 SIRT6 Author keyword 47 69% 2% 40
8 SIRT4 Author keyword 31 92% 0% 12
9 DEACETYLASE Author keyword 28 39% 2% 56
10 SIRTUIN 1 Author keyword 27 37% 2% 58

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 SIRT1 311 47% 20% 494 Search SIRT1 Search SIRT1
2 SIRTUIN 183 61% 8% 194 Search SIRTUIN Search SIRTUIN
3 SIRT3 157 79% 4% 101 Search SIRT3 Search SIRT3
4 SIRTUINS 153 52% 8% 208 Search SIRTUINS Search SIRTUINS
5 SIRT2 106 81% 3% 64 Search SIRT2 Search SIRT2
6 SIRT5 65 95% 1% 21 Search SIRT5 Search SIRT5
7 SIRT6 47 69% 2% 40 Search SIRT6 Search SIRT6
8 SIRT4 31 92% 0% 12 Search SIRT4 Search SIRT4
9 DEACETYLASE 28 39% 2% 56 Search DEACETYLASE Search DEACETYLASE
10 SIRTUIN 1 27 37% 2% 58 Search SIRTUIN+1 Search SIRTUIN+1

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 CALORIE RESTRICTION 281 33% 27% 696
2 SIRTUINS 266 61% 11% 284
3 SIR2 LIKE PROTEINS 161 77% 4% 111
4 DEACETYLASE 153 38% 13% 325
5 PROTEIN DEACETYLASES 150 71% 5% 120
6 DEPENDENT DEACETYLASE 150 83% 3% 84
7 SMALL MOLECULE ACTIVATORS 110 51% 6% 153
8 MAMMALIAN SIRTUINS 99 88% 2% 46
9 HISTONE PROTEIN DEACETYLASES 93 83% 2% 53
10 REGULATES SIRT1 93 88% 2% 44

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
SIRT1 and other sirtuins in metabolism 2014 52 114 74%
Sirtuins as regulators of metabolism and healthspan 2012 293 152 70%
Small molecule SIRT1 activators for the treatment of aging and age-related diseases 2014 48 98 58%
Small-Molecule Allosteric Activators of Sirtuins 2014 36 118 69%
Sirtuin modulators: an updated patent review (2012-2014) 2015 2 25 96%
Recent progress in the biology and physiology of sirtuins 2009 490 82 80%
Mammalian Sirtuins: Biological Insights and Disease Relevance 2010 548 276 60%
The growing landscape of lysine acetylation links metabolism and cell signalling 2014 53 156 35%
Mitochondrial sirtuins: Emerging roles in metabolic regulations, energy homeostasis and diseases 2015 2 135 76%
Role of sirtuins in chronic obstructive pulmonary disease 2015 4 114 41%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 PAUL F GLENN 25 77% 0.7% 17
2 PAUL F GLENN S BIOL MECH AGING 16 48% 1.0% 25
3 SIRTRIS 9 83% 0.2% 5
4 GLENN S BIOL MECH AGING 7 64% 0.3% 7
5 GLENN SCI AGING 7 64% 0.3% 7
6 COMM CELLULAR MOL PHYSIOL 6 53% 0.3% 8
7 CELL SENESCENCE 5 31% 0.6% 14
8 GLENN S AGING 4 75% 0.1% 3
9 INTEGRAT SYST PHYSIOL LISP NCEM 4 75% 0.1% 3
10 YORKSHIRE CANC UNIT P53 4 75% 0.1% 3

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000087394 VISFATIN//NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE//NAMPT
2 0.0000085433 SIR COMPLEX//SIR3//SIR PROTEINS
3 0.0000081488 RESVERATROL//PTEROSTILBENE//PICEATANNOL
4 0.0000072616 FOXO//FOXO3A//FOXO1
5 0.0000061508 WLDS//NMNAT//NAD BIOSYNTHESIS
6 0.0000056237 CHRONOLOGICAL LIFESPAN//YEAST APOPTOSIS//RETROGRADE RESPONSE
7 0.0000053970 PGC 1 ALPHA//ESTROGEN RELATED RECEPTOR ALPHA//MITOCHONDRIAL BIOGENESIS
8 0.0000046612 CALORIC RESTRICTION//CALORIE RESTRICTION//DIETARY RESTRICTION
9 0.0000046350 MYST//MOZ//HISTONE ACETYLTRANSFERASE
10 0.0000041236 DAF 16//DAF 12//LIFESPAN