Class information for:
Level 1: S ADENOSYLMETHIONINE DECARBOXYLASE//CATIONIC DIAMIDINES//DFMO RESISTANCE

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
15033 666 32.2 59%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
951 10331 POLYAMINES//SPERMIDINE//PUTRESCINE

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 S ADENOSYLMETHIONINE DECARBOXYLASE Author keyword 5 18% 4% 27
2 CATIONIC DIAMIDINES Author keyword 3 100% 0% 3
3 DFMO RESISTANCE Author keyword 3 100% 0% 3
4 S ADENOSYLMETHIONINE METABOLISM Author keyword 3 100% 0% 3
5 PUTRESCINE UPTAKE Author keyword 3 60% 0% 3
6 SINEFUNGIN Author keyword 2 24% 1% 9
7 MDL 27695 Author keyword 2 67% 0% 2
8 PYRUVOYL COFACTOR Author keyword 2 67% 0% 2
9 PYRUVOYL DEPENDENT ENZYMES Author keyword 2 67% 0% 2
10 ZN CU COUPLE Author keyword 2 50% 0% 3

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 S ADENOSYLMETHIONINE DECARBOXYLASE 5 18% 4% 27 Search S+ADENOSYLMETHIONINE+DECARBOXYLASE Search S+ADENOSYLMETHIONINE+DECARBOXYLASE
2 CATIONIC DIAMIDINES 3 100% 0% 3 Search CATIONIC+DIAMIDINES Search CATIONIC+DIAMIDINES
3 DFMO RESISTANCE 3 100% 0% 3 Search DFMO+RESISTANCE Search DFMO+RESISTANCE
4 S ADENOSYLMETHIONINE METABOLISM 3 100% 0% 3 Search S+ADENOSYLMETHIONINE+METABOLISM Search S+ADENOSYLMETHIONINE+METABOLISM
5 PUTRESCINE UPTAKE 3 60% 0% 3 Search PUTRESCINE+UPTAKE Search PUTRESCINE+UPTAKE
6 SINEFUNGIN 2 24% 1% 9 Search SINEFUNGIN Search SINEFUNGIN
7 MDL 27695 2 67% 0% 2 Search MDL+27695 Search MDL+27695
8 PYRUVOYL COFACTOR 2 67% 0% 2 Search PYRUVOYL+COFACTOR Search PYRUVOYL+COFACTOR
9 PYRUVOYL DEPENDENT ENZYMES 2 67% 0% 2 Search PYRUVOYL+DEPENDENT+ENZYMES Search PYRUVOYL+DEPENDENT+ENZYMES
10 ZN CU COUPLE 2 50% 0% 3 Search ZN+CU+COUPLE Search ZN+CU+COUPLE

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 PUTRESCINE STIMULATION 27 92% 2% 11
2 L METHIONINE DECARBOXYLASE 17 42% 5% 31
3 TRYPANOCIDAL ACTIVITIES 9 59% 2% 10
4 S ADENOSYLMETHIONINE DECARBOXYLASE 8 13% 9% 59
5 BRUCEI RHODESIENSE INFECTIONS 7 50% 2% 10
6 DL ALPHA DIFLUOROMETHYLORNITHINE 7 21% 4% 28
7 ESTER INTERMEDIATE 6 48% 2% 10
8 AMERICAN LEISHMANIA 6 80% 1% 4
9 PUTRESCINE ACTIVATION 6 80% 1% 4
10 BIFUNCTIONAL ORNITHINE DECARBOXYLASE 6 47% 1% 9

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Targeting the polyamine biosynthetic enzymes: a promising approach to therapy of African sleeping sickness, Chagas' disease, and leishmaniasis 2007 85 50 68%
Polyamine homoeostasis as a drug target in pathogenic protozoa: peculiarities and possibilities 2011 23 134 53%
PYRUVOYL-DEPENDENT ENZYMES 1990 175 58 66%
S-Adenosylmethionine decarboxylase 2009 27 38 61%
Structural biology of S-adenosylmethionine decarboxylase 2010 12 44 64%
Targeting polyamines of parasitic protozoa in chemotherapy 2001 90 55 47%
Assessing the polyamine metabolism of Plasmodium falciparum as chemotherapeutic target 2008 24 66 53%
Regulation and function of polyamines in African trypanosomes 2012 9 75 44%
Functional consequences of perturbing polyamine metabolism in the malaria parasite, Plasmodium falciparum 2010 11 54 48%
S-ADENOSYLMETHIONINE DECARBOXYLASE AS AN ENZYME TARGET FOR THERAPY 1992 85 69 64%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ.
in class
1 FUNDAC LELOIR 1 50% 0.3% 2
2 HASKINS 1 22% 0.6% 4
3 HASKINS S INC 1 21% 0.5% 3
4 DPTO CIENCIAS BIOMED 1 50% 0.2% 1
5 FISIOL FARMACOL TOXICOL INTOXCAL 1 50% 0.2% 1
6 HUBEI TUMOR MICROENVIRONM IMMUNOTHER Y 1 50% 0.2% 1
7 IIBBACONICET 1 50% 0.2% 1
8 UMR ICMMO 8182 1 50% 0.2% 1
9 SECT OURCES 1 19% 0.5% 3
10 INTOXCAL 0 13% 0.5% 3

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000239403 POLYAMINES//SPERMIDINE SPERMINE N 1 ACETYLTRANSFERASE//SPERMINE OXIDASE
2 0.0000175990 ANTIZYME INHIBITOR//ANTIZYME//ORNITHINE DECARBOXYLASE
3 0.0000158795 TRYPANOTHIONE REDUCTASE//TRYPANOTHIONE//TRYPAREDOXIN
4 0.0000152880 PL MICROBIOLAOBA KU//CALDOPENTAMINE//HOMOSPERMIDINE
5 0.0000135253 GLYCINE REDUCTASE//EUBACTERIUM ACIDAMINOPHILUM//SARCOSINE REDUCTASE
6 0.0000114669 METHYLTHIOADENOSINE PHOSPHORYLASE//MTAP//L ALANOSINE
7 0.0000107889 RIBOSOME MODULATION FACTOR//AMINE PHARMA//POLYAMINE MODULON
8 0.0000106374 TRYPANOSOMA BRUCEI GAMBIENSE//HUMAN AFRICAN TRYPANOSOMIASIS//MELARSOPROL
9 0.0000102278 GLYCOSOME//UNIDAD BIOQUIM PARASITOS//GLYCOSOMES
10 0.0000081335 AMBAZONE//ADENOSYLMETHIONINE DECARBOXYLASE INHIBITORS//DIAMINE OXIDASE INHIBITORS