Class information for:
Level 1: 7 HYDROXYMETHOTREXATE//GLUCARPIDASE//HIGH DOSE METHOTREXATE

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
14826 678 24.8 53%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
1587 6631 FOLATE RECEPTOR//REDUCED FOLATE CARRIER//DIHYDROFOLATE REDUCTASE

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 7 HYDROXYMETHOTREXATE Author keyword 21 61% 3% 23
2 GLUCARPIDASE Author keyword 21 90% 1% 9
3 HIGH DOSE METHOTREXATE Author keyword 11 27% 5% 33
4 CARBOXYPEPTIDASE G2 Author keyword 6 40% 2% 12
5 7 HYDROXY METHOTREXATE Author keyword 4 75% 0% 3
6 METHOTREXATE TOXICITY Author keyword 4 36% 1% 9
7 DELAYED ELIMINATION Author keyword 3 60% 0% 3
8 7 OH METHOTREXATE Author keyword 2 67% 0% 2
9 LEUCOVORIN RESCUE Author keyword 2 43% 0% 3
10 2 4 DIAMINO N 10 METHYLPTEROIC ACID Author keyword 1 100% 0% 2

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 7 HYDROXYMETHOTREXATE 21 61% 3% 23 Search 7+HYDROXYMETHOTREXATE Search 7+HYDROXYMETHOTREXATE
2 GLUCARPIDASE 21 90% 1% 9 Search GLUCARPIDASE Search GLUCARPIDASE
3 HIGH DOSE METHOTREXATE 11 27% 5% 33 Search HIGH+DOSE+METHOTREXATE Search HIGH+DOSE+METHOTREXATE
4 CARBOXYPEPTIDASE G2 6 40% 2% 12 Search CARBOXYPEPTIDASE+G2 Search CARBOXYPEPTIDASE+G2
5 7 HYDROXY METHOTREXATE 4 75% 0% 3 Search 7+HYDROXY+METHOTREXATE Search 7+HYDROXY+METHOTREXATE
6 METHOTREXATE TOXICITY 4 36% 1% 9 Search METHOTREXATE+TOXICITY Search METHOTREXATE+TOXICITY
7 DELAYED ELIMINATION 3 60% 0% 3 Search DELAYED+ELIMINATION Search DELAYED+ELIMINATION
8 7 OH METHOTREXATE 2 67% 0% 2 Search 7+OH+METHOTREXATE Search 7+OH+METHOTREXATE
9 LEUCOVORIN RESCUE 2 43% 0% 3 Search LEUCOVORIN+RESCUE Search LEUCOVORIN+RESCUE
10 2 4 DIAMINO N 10 METHYLPTEROIC ACID 1 100% 0% 2 Search 2+4+DIAMINO+N+10+METHYLPTEROIC+ACID Search 2+4+DIAMINO+N+10+METHYLPTEROIC+ACID

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 7 HYDROXYMETHOTREXATE 42 57% 7% 50
2 LEUCOVORIN RESCUE 24 55% 4% 30
3 7 HYDROXY METHOTREXATE 21 71% 3% 17
4 G2 RESCUE 14 100% 1% 7
5 SERUM METHOTREXATE 12 86% 1% 6
6 CARBOXYPEPTIDASE G2 RESCUE 10 63% 1% 10
7 PLASMA METHOTREXATE 9 83% 1% 5
8 G M2 4 67% 1% 4
9 NSC 740 4 67% 1% 4
10 CITROVORUM FACTOR RESCUE 4 33% 1% 10

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
How Long Can Folinic Acid Rescue Be Delayed After High-Dose Methotrexate Without Toxicity? 2014 6 22 32%
High-dose methotrexate-induced nephrotoxicity in patients with osteosarcoma - Incidence, treatment, and outcome 2004 72 67 45%
Glucarpidase to combat toxic levels of methotrexate in patients 2012 10 45 47%
Separation methods for methotrexate, its structural analogues and metabolites 2001 37 126 46%
Accidental shortening time of high dose methotrexate infusion: case report and literature review 2013 1 7 71%
Glucarpidase Intervention for Delayed Methotrexate Clearance 2014 0 15 87%
Rational administration schedule for high-dose methotrexate in patients with primary central nervous system lymphoma 2012 7 71 34%
Bayesian estimation of methotrexate pharmacokinetic parameters and area under the curve in children and young adults with localised osteosarcoma 2002 24 22 32%
High-dose methotrexate in acute lymphoblastic leukemia: Where is the evidence for its continued use? 2005 16 28 21%
RESCUE AFTER INTERMEDIATE AND HIGH-DOSE METHOTREXATE - BACKGROUND, RATIONALE, AND CURRENT PRACTICE 1990 14 23 52%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ.
in class
1 PHARM PHARMACOKINET THER EUT DRUG MONITOR 1 100% 0.3% 2
2 DENTISTRY PHARM 3126 1 50% 0.1% 1
3 ONCOL 91 RIDING HOUSE ST 1 50% 0.1% 1
4 PINDA 1 50% 0.1% 1
5 SEZ CHEMIOTER IA TUMORI PARATO LOCOMOTORE 1 50% 0.1% 1
6 UNITE ONCO HEMATOL PEDIAT 1 50% 0.1% 1
7 UPCO 1 50% 0.1% 1
8 VNCC 1 50% 0.1% 1
9 HEAD NEPHROL 0 33% 0.1% 1
10 PEDIAT PHARMACOKINET 0 33% 0.1% 1

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000188310 INTESTINAL DAMAGE//SOYBEAN CONCENTRATE//ADJUVANT FREUND INDUCED ARTHRITIS
2 0.0000188105 METHOTREXATE//METHOTREXATE POLYGLUTAMATES//MX 68
3 0.0000159349 REDUCED FOLATE CARRIER//FOLYLPOLYGLUTAMATE SYNTHETASE//HEREDITARY FOLATE MALABSORPTION
4 0.0000097362 ETOPOSIDE PHOSPHATE//ETOPOSIDE//ORAL ETOPOSIDE
5 0.0000077399 COGNITIVE LATE EFFECTS//INTRATHECAL METHOTREXATE//SOMNOLENCE SYNDROME
6 0.0000073393 OSTEOSARCOMA//METASTATIC OSTEOSARCOMA//SEZ CHEMIOTER IA
7 0.0000073327 BENZOYLATED DEAE CELLULOSE CHROMATOGRAPHY//POLYADENOSINE DIPHOSPHATE RIBOSE//N NITROSO N ETHYLUREA
8 0.0000067817 ASAN FDN//DA 125//MED DIAGNOST PATHOL
9 0.0000061178 BIOCHEMICAL MODULATION//LEUCOVORIN//FOLINIC ACID
10 0.0000057262 GRP PEPTIDE CHEM//BRANCHED POLYPEPTIDES//HUNGARIAN SCI PEPTIDE CHEM GRP