Class information for:
Level 1: SYK//SPLEEN TYROSINE KINASE//R788

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
14817 679 46.1 93%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
313 17635 X LINKED AGAMMAGLOBULINEMIA//BRUTONS TYROSINE KINASE//BTK

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 SYK Author keyword 38 31% 15% 103
2 SPLEEN TYROSINE KINASE Author keyword 22 55% 4% 28
3 R788 Author keyword 12 86% 1% 6
4 SPLEEN TYROSINE KINASE SYK Author keyword 9 55% 2% 12
5 R406 Author keyword 9 67% 1% 8
6 FOSTAMATINIB Author keyword 8 48% 2% 12
7 ZAP 70 Author keyword 6 15% 5% 37
8 SYK KINASE Author keyword 5 28% 2% 14
9 SYK INHIBITOR Author keyword 4 67% 1% 4
10 RAST SECT Address 3 57% 1% 4

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 SYK 38 31% 15% 103 Search SYK Search SYK
2 SPLEEN TYROSINE KINASE 22 55% 4% 28 Search SPLEEN+TYROSINE+KINASE Search SPLEEN+TYROSINE+KINASE
3 R788 12 86% 1% 6 Search R788 Search R788
4 SPLEEN TYROSINE KINASE SYK 9 55% 2% 12 Search SPLEEN+TYROSINE+KINASE+SYK Search SPLEEN+TYROSINE+KINASE+SYK
5 R406 9 67% 1% 8 Search R406 Search R406
6 FOSTAMATINIB 8 48% 2% 12 Search FOSTAMATINIB Search FOSTAMATINIB
7 ZAP 70 6 15% 5% 37 Search ZAP+70 Search ZAP+70
8 SYK KINASE 5 28% 2% 14 Search SYK+KINASE Search SYK+KINASE
9 SYK INHIBITOR 4 67% 1% 4 Search SYK+INHIBITOR Search SYK+INHIBITOR
10 SYK INHIBITORS 3 50% 1% 4 Search SYK+INHIBITORS Search SYK+INHIBITORS

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 P72SYK 20 48% 4% 30
2 INTERDOMAIN B 17 100% 1% 8
3 SPLEEN TYROSINE KINASE 14 33% 5% 36
4 R406 14 100% 1% 7
5 SYK 13 16% 11% 74
6 ZAP 70 KINASE 11 46% 3% 18
7 TYROSINE KINASE SYK 11 28% 5% 33
8 ZAP 70 10 15% 9% 60
9 PHOSPHORYLATED ITAM PEPTIDE 10 63% 1% 10
10 SYK KINASE 9 38% 3% 18

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
The SYK tyrosine kinase: a crucial player in diverse biological functions 2010 282 185 38%
The structure, regulation, and function of ZAP-70 2009 76 75 57%
Calling in SYK: SYK's dual role as a tumor promoter and tumor suppressor in cancer 2015 1 111 50%
Tyrosine kinase SYK: essential functions for immunoreceptor signalling 2000 231 53 53%
Spleen tyrosine kinase inhibitors: a review of the patent literature 2010-2013 2014 3 25 84%
Getting Syk: spleen tyrosine kinase as a therapeutic target 2014 5 103 56%
Small-molecule inhibitors of spleen tyrosine kinase as therapeutic agents for immune disorders: will promise meet expectations? 2014 3 41 71%
Spleen tyrosine kinases: biology, therapeutic targets and drugs 2010 43 65 57%
The Syk family of protein tyrosine kinases in T-cell activation and development 1998 178 77 56%
Protein kinase inhibitors in the treatment of inflammatory and autoimmune diseases 2014 14 92 20%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ.
in class
1 RAST SECT 3 57% 0.6% 4
2 MED EXPT EDUC 2 67% 0.3% 2
3 MOL ONCOL DRUG DISCOVERY PROGRAM 2 36% 0.6% 4
4 JONATHAN JAQUES CANC 1 50% 0.3% 2
5 CARDIOVASC PHYSIOL PATHOPHYSIOL 1 33% 0.4% 3
6 INFLAMMAT DISCOVERY THER EUT AREA 1 33% 0.4% 3
7 RECEPTORS SIGNAL TRANSDUCT SECT 1 18% 0.7% 5
8 PROTEOMCHUO KU 1 27% 0.4% 3
9 MTA SE LENDULET INFLAMMAT PHYSIOL GRP 1 33% 0.3% 2
10 CNRSINSERMU661 1 50% 0.1% 1

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000232138 SLP 76//LINKER FOR ACTIVATION OF T CELLS//SECT LYMPHOCYTE SIGNALING
2 0.0000178867 CELLULAR INJURY//TCR ZETA CHAIN//CD3 GAMMA
3 0.0000154740 VAV//VAV1//VAV3
4 0.0000145321 CBL B//CBL//CIN85
5 0.0000134714 CD45//CD45 ISOFORMS//P56LCK
6 0.0000130816 X LINKED AGAMMAGLOBULINEMIA//BRUTONS TYROSINE KINASE//BTK
7 0.0000103447 SURFACE IGM//IG ALPHA//MEMBRANE IMMUNOGLOBULIN
8 0.0000085739 TOFACITINIB//JAK3//CP 690 550
9 0.0000085405 GRB2//SH2 DOMAIN//SH3 DOMAIN
10 0.0000080688 NEUTROPHIL SIGNALLING GRP//MOL SIGNALLING GRP//FFP 18