Class information for:
Level 1: EFAVIRENZ//CYP2B6//NEVIRAPINE

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
13901 742 34.8 80%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
26 34435 ANTIRETROVIRAL THERAPY//HIV//NEVIRAPINE

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 EFAVIRENZ Author keyword 67 32% 23% 174
2 CYP2B6 Author keyword 52 46% 12% 86
3 NEVIRAPINE Author keyword 29 21% 17% 124
4 CYP2B6 POLYMORPHISM Author keyword 8 100% 1% 5
5 BAMRASNARADURA INFECT DIS Address 5 28% 2% 15
6 UGANDANS Author keyword 4 67% 1% 4
7 CNS SIDE EFFECTS Author keyword 3 50% 1% 5
8 CYP2B6 516G T Author keyword 3 100% 0% 3
9 4 HYDROXYBUPROPION Author keyword 2 67% 0% 2
10 RODOLPHE MERIEUX Address 2 67% 0% 2

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 EFAVIRENZ 67 32% 23% 174 Search EFAVIRENZ Search EFAVIRENZ
2 CYP2B6 52 46% 12% 86 Search CYP2B6 Search CYP2B6
3 NEVIRAPINE 29 21% 17% 124 Search NEVIRAPINE Search NEVIRAPINE
4 CYP2B6 POLYMORPHISM 8 100% 1% 5 Search CYP2B6+POLYMORPHISM Search CYP2B6+POLYMORPHISM
5 UGANDANS 4 67% 1% 4 Search UGANDANS Search UGANDANS
6 CNS SIDE EFFECTS 3 50% 1% 5 Search CNS+SIDE+EFFECTS Search CNS+SIDE+EFFECTS
7 CYP2B6 516G T 3 100% 0% 3 Search CYP2B6+516G++T Search CYP2B6+516G++T
8 4 HYDROXYBUPROPION 2 67% 0% 2 Search 4+HYDROXYBUPROPION Search 4+HYDROXYBUPROPION
9 NEUROPSYCHIATRIC SIDE EFFECTS 2 36% 1% 4 Search NEUROPSYCHIATRIC+SIDE+EFFECTS Search NEUROPSYCHIATRIC+SIDE+EFFECTS
10 EFAVIRENZ CONCENTRATION 1 100% 0% 2 Search EFAVIRENZ+CONCENTRATION Search EFAVIRENZ+CONCENTRATION

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 CYP2B6 32 39% 9% 65
2 CYTOCHROME P4502B6 CYP2B6 30 84% 2% 16
3 600 MG DAY 24 91% 1% 10
4 ANTITUBERCULAR THERAPY 19 68% 2% 17
5 CYTOCHROME P4502B6 19 46% 4% 31
6 CYP2B6 983T GREATER THAN C POLYMORPHISM 18 83% 1% 10
7 BUPROPION HYDROXYLATION 16 46% 4% 26
8 CYP2B6 POLYMORPHISMS 15 88% 1% 7
9 CYP2B6 POLYMORPHISM 12 75% 1% 9
10 DRUG EFAVIRENZ 11 100% 1% 6

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
A Systematic Review of the Psychiatric Side-Effects of Efavirenz 2011 26 37 65%
Polymorphic CYP2B6: molecular mechanisms and emerging clinical significance 2007 114 97 49%
Pharmacological Interactions Between Rifampicin and Antiretroviral Drugs: Challenges and Research Priorities for Resource-Limited Settings 2015 1 101 39%
Neuronal toxicity of efavirenz: a systematic review 2013 7 41 51%
Efavirenz in the therapy of HIV infection 2010 29 60 55%
Neuropsychiatric side effects of efavirenz therapy 2007 36 33 73%
Dose adjustment of the non-nucleoside reverse transcriptase inhibitors during concurrent rifampicin-containing tuberculosis therapy: one size does not fit all 2010 15 81 67%
Impact of CYP polymorphisms, ethnicity and sex differences in metabolism on dosing strategies: the case of efavirenz 2014 1 71 70%
Clinical impact of patient population differences and genomic variation in efavirenz therapy 2008 31 51 55%
Neuropsychiatric Symptoms Associated with Efavirenz: Prevalence, Correlates, and Management. A Neurobehavioral Review 2009 27 27 52%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 BAMRASNARADURA INFECT DIS 5 28% 2.0% 15
2 RODOLPHE MERIEUX 2 67% 0.3% 2
3 BAMRASNARADURA 2 43% 0.4% 3
4 AIDS UNIT INTERNAL MED 1 100% 0.3% 2
5 CLIN CHEM AKC 1 50% 0.3% 2
6 IPM STUDY 1 100% 0.3% 2
7 LLUITA CONTRA SIDA FDN 1 33% 0.4% 3
8 HARRIET SHEZI CHILDRENS CLIN 1 21% 0.7% 5
9 AIDS CARE UNIT 1 30% 0.4% 3
10 LIVERPOOL HIV PHARMACOL GRP 1 40% 0.3% 2

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000258514 ATAZANAVIR//RITONAVIR//LOPINAVIR
2 0.0000189907 ETRAVIRINE//RILPIVIRINE//TMC125
3 0.0000167827 ROYAL FREE HIV MED//CD4 CELL COUNT//X BICHAT MED
4 0.0000165409 BUPROPION//HYDROXYBUPROPION//WELLBUTRIN
5 0.0000108450 DRUG INDUCED HYPERSENSITIVITY SYNDROME//HLA B5701//HYPERSENSITIVITY SYNDROME
6 0.0000084572 FLUORESCENT FOCUS ASSAY//FUYOU BRANCH//GLOBAL NEUROL PROGRAM
7 0.0000079015 HIV HCV CO INFECTION//HIV HCV COINFECTION//COINFECTION
8 0.0000078016 METHADONE//EDDP//2 ETHYLIDENE 1 5 DIMETHYL 3 3 DIPHENYLPYRROLIDINE
9 0.0000067326 CYP3A//COCKTAIL//MECHANISM BASED INHIBITION
10 0.0000066843 PREGNANE X RECEPTOR//PXR//CONSTITUTIVE ANDROSTANE RECEPTOR