Class information for:
Level 1: INDIVIDUAL BIOEQUIVALENCE//HIGHLY VARIABLE DRUGS//BIOEQUIVALENCE

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
12997 803 19.2 48%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
1692 6172 FAMILYWISE ERROR RATE//MULTIPLE TESTING//FALSE DISCOVERY RATE

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 INDIVIDUAL BIOEQUIVALENCE Author keyword 67 87% 4% 33
2 HIGHLY VARIABLE DRUGS Author keyword 52 87% 3% 26
3 BIOEQUIVALENCE Author keyword 43 16% 31% 251
4 POPULATION BIOEQUIVALENCE Author keyword 35 89% 2% 16
5 AVERAGE BIOEQUIVALENCE Author keyword 25 73% 2% 19
6 TWO ONE SIDED TESTS PROCEDURE Author keyword 18 89% 1% 8
7 SCALED BIOEQUIVALENCE LIMITS Author keyword 11 100% 1% 6
8 PHARMACOKINETIC SIMULATIONS Author keyword 9 83% 1% 5
9 SUBJECT BY FORMULATION INTERACTION Author keyword 8 100% 1% 5
10 INTERVAL HYPOTHESIS Author keyword 8 62% 1% 8

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 INDIVIDUAL BIOEQUIVALENCE 67 87% 4% 33 Search INDIVIDUAL+BIOEQUIVALENCE Search INDIVIDUAL+BIOEQUIVALENCE
2 HIGHLY VARIABLE DRUGS 52 87% 3% 26 Search HIGHLY+VARIABLE+DRUGS Search HIGHLY+VARIABLE+DRUGS
3 BIOEQUIVALENCE 43 16% 31% 251 Search BIOEQUIVALENCE Search BIOEQUIVALENCE
4 POPULATION BIOEQUIVALENCE 35 89% 2% 16 Search POPULATION+BIOEQUIVALENCE Search POPULATION+BIOEQUIVALENCE
5 AVERAGE BIOEQUIVALENCE 25 73% 2% 19 Search AVERAGE+BIOEQUIVALENCE Search AVERAGE+BIOEQUIVALENCE
6 TWO ONE SIDED TESTS PROCEDURE 18 89% 1% 8 Search TWO+ONE+SIDED+TESTS+PROCEDURE Search TWO+ONE+SIDED+TESTS+PROCEDURE
7 SCALED BIOEQUIVALENCE LIMITS 11 100% 1% 6 Search SCALED+BIOEQUIVALENCE+LIMITS Search SCALED+BIOEQUIVALENCE+LIMITS
8 PHARMACOKINETIC SIMULATIONS 9 83% 1% 5 Search PHARMACOKINETIC+SIMULATIONS Search PHARMACOKINETIC+SIMULATIONS
9 SUBJECT BY FORMULATION INTERACTION 8 100% 1% 5 Search SUBJECT+BY+FORMULATION+INTERACTION Search SUBJECT+BY+FORMULATION+INTERACTION
10 INTERVAL HYPOTHESIS 8 62% 1% 8 Search INTERVAL+HYPOTHESIS Search INTERVAL+HYPOTHESIS

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 INDIVIDUAL BIOEQUIVALENCE 62 63% 8% 62
2 HIGHLY VARIABLE DRUGS 45 62% 6% 47
3 SCALED AVERAGE BIOEQUIVALENCE 35 86% 2% 18
4 BIOAVAILABILITY BIOEQUIVALENCE 26 87% 2% 13
5 LEVELING OFF PROPERTIES 21 85% 1% 11
6 COMPARATIVE BIOAVAILABILITY TRIALS 20 56% 3% 25
7 SIDED TESTS PROCEDURE 16 48% 3% 25
8 TESTING EQUIVALENCE 11 65% 1% 11
9 AVERAGE BIOEQUIVALENCE 11 60% 1% 12
10 BIOEQUIVALENCE TRIALS 9 52% 1% 12

Journals

Reviews


Title Publ. year Cit. Active
references		 % act. ref.
to same field
Evaluation of Bioequivalence for Highly Variable Drugs with Scaled Average Bioequivalence 2009 18 64 80%
Using Partial Area for Evaluation of Bioavailability and Bioequivalence 2011 9 15 87%
Individual bioequivalence - New concepts in the statistical assessment of bioequivalence metrics 1997 52 11 100%
Implementation of a Reference-Scaled Average Bioequivalence Approach for Highly Variable Generic Drug Products by the US Food and Drug Administration 2012 9 15 87%
Novel methods to assess bioequivalence 2011 4 40 80%
Bioequivalence Requirements in the European Union: Critical Discussion 2012 11 14 57%
Variability and Impact on Design of Bioequivalence Studies 2010 10 25 72%
Current regulatory approaches of bioequivalence testing 2012 6 60 72%
Requirements for generic antiepileptic medicines: a clinical perspective 2011 5 37 43%
Measures of exposure versus measures of rate and extent of absorption 2001 27 34 71%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 PHARMACOKINET SERV 6 80% 0.5% 4
2 PHARMALYT INC 4 75% 0.4% 3
3 PHARMACOL CLIN EVALUAT 3 39% 0.9% 7
4 REGULATORY AFFAIRS QUAL 3 50% 0.5% 4
5 BIOMETR PHARMACOKINET RD 3 60% 0.4% 3
6 BIOTECHNOL CLIN DEV 3 60% 0.4% 3
7 P DIS BRANCH BACTERIAL MYCOT DIS 2 67% 0.2% 2
8 PHARMACOKINET ANALYT STUDIES 2 67% 0.2% 2
9 INVENT FARMA GRP 2 50% 0.4% 3
10 OFF PHARMACEUT SCI 2 11% 2.2% 18

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000173911 NON INFERIORITY MARGIN//NON INFERIORITY//THREE ARM DESIGN
2 0.0000101595 PROBABILITY OF CORRECT SELECTION//CORRECT SELECTION//PROBABILITY OF A CORRECT SELECTION
3 0.0000097736 JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS//DISTRIBUTION CLEARANCE//CURVE MOMENTS
4 0.0000088113 GENERIC SUBSTITUTION//GENERIC DRUGS//REFERENCE PRICING
5 0.0000082011 PARALLEL LINE BIOASSAY//SLOPE RATIO BIOASSAY//FIELLER METHOD
6 0.0000070505 DISSOLUTION TECHNOLOGIES//BIORELEVANT MEDIA//BIOWAIVER
7 0.0000065160 DIRECTION OF DEPENDENCE//HOMOGENEITY OF COVARIANCE MATRICES//PITMAN MORGAN TEST
8 0.0000062003 BEHRENS FISHER DISTRIBUTION//PILOT TRIALS//COPC
9 0.0000059240 ACCURACY PROFILE//ANALYTICAL METHOD TRANSFER//LERMDV
10 0.0000058110 JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS//NONMEM//INDIRECT RESPONSE MODELS