Class information for:
Level 1: PROTEINASE K INHIBITOR//HUMAN LEUKOCYTE ELASTASE//HUMAN LEUKOCYTE ELASTASE HLE

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
12939 807 30.5 55%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
2487 3478 ELAFIN//SLPI//SECRETORY LEUKOCYTE PROTEASE INHIBITOR

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 PROTEINASE K INHIBITOR Author keyword 8 100% 1% 5
2 HUMAN LEUKOCYTE ELASTASE Author keyword 3 25% 1% 12
3 HUMAN LEUKOCYTE ELASTASE HLE Author keyword 3 57% 0% 4
4 FR134043 Author keyword 3 100% 0% 3
5 PEPTIDYL CARBAMATE Author keyword 3 100% 0% 3
6 PORCINE PANCREATIC ELASTASE Author keyword 3 37% 1% 7
7 ELASTASE INHIBITOR Author keyword 2 20% 1% 11
8 4H 3 1 BENZOXAZIN 4 ONE Author keyword 2 67% 0% 2
9 HETEROCYCLIC INHIBITORS Author keyword 2 67% 0% 2
10 ELASTASE INHIBITORS Author keyword 2 23% 1% 7

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 PROTEINASE K INHIBITOR 8 100% 1% 5 Search PROTEINASE+K+INHIBITOR Search PROTEINASE+K+INHIBITOR
2 HUMAN LEUKOCYTE ELASTASE 3 25% 1% 12 Search HUMAN+LEUKOCYTE+ELASTASE Search HUMAN+LEUKOCYTE+ELASTASE
3 HUMAN LEUKOCYTE ELASTASE HLE 3 57% 0% 4 Search HUMAN+LEUKOCYTE+ELASTASE+HLE Search HUMAN+LEUKOCYTE+ELASTASE+HLE
4 FR134043 3 100% 0% 3 Search FR134043 Search FR134043
5 PEPTIDYL CARBAMATE 3 100% 0% 3 Search PEPTIDYL+CARBAMATE Search PEPTIDYL+CARBAMATE
6 PORCINE PANCREATIC ELASTASE 3 37% 1% 7 Search PORCINE+PANCREATIC+ELASTASE Search PORCINE+PANCREATIC+ELASTASE
7 ELASTASE INHIBITOR 2 20% 1% 11 Search ELASTASE+INHIBITOR Search ELASTASE+INHIBITOR
8 4H 3 1 BENZOXAZIN 4 ONE 2 67% 0% 2 Search 4H+3+1+BENZOXAZIN+4+ONE Search 4H+3+1+BENZOXAZIN+4+ONE
9 HETEROCYCLIC INHIBITORS 2 67% 0% 2 Search HETEROCYCLIC+INHIBITORS Search HETEROCYCLIC+INHIBITORS
10 ELASTASE INHIBITORS 2 23% 1% 7 Search ELASTASE+INHIBITORS Search ELASTASE+INHIBITORS

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 HUMAN LEUKOCYTE ELASTASE 60 25% 26% 209
2 BETA LACTAM INHIBITORS 40 69% 4% 34
3 184 A RESOLUTION 32 88% 2% 15
4 ALTERNATE SUBSTRATE INHIBITORS 27 83% 2% 15
5 PORCINE PANCREATIC ELASTASE 18 25% 8% 64
6 4H 3 1 BENZOXAZIN 4 ONES 18 57% 3% 21
7 MECHANISM BASED INHIBITORS 16 26% 6% 52
8 HUMAN NEUTROPHIL ELASTASE 13 17% 9% 73
9 BENZOXAZINONES 12 40% 3% 23
10 CEPHEM 4 KETONES 11 100% 1% 6

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Neutrophil elastase inhibitors: recent advances in the development of mechanism-based and nonelectrophilic inhibitors 2012 7 29 66%
SYNTHETIC INHIBITORS OF ELASTASE 1994 201 197 58%
Irreversible inhibitors of serine, cysteine, and threonine proteases 2002 478 656 22%
Neutrophil elastase inhibitors 2011 21 85 22%
HUMAN-LEUKOCYTE AND PORCINE PANCREATIC ELASTASE - X-RAY CRYSTAL-STRUCTURES, MECHANISM, SUBSTRATE-SPECIFICITY, AND MECHANISM-BASED INHIBITORS 1989 343 65 49%
Advances in the Chemistry of Saccharins: From Synthetic Novelties Towards Biologically Active Compounds 2010 11 62 35%
Strategies for the inhibition of serine proteases 2001 54 202 33%
Protease inhibitors: Current status and future prospects 2000 667 303 10%
Succinimide and saccharin-based enzyme-activated inhibitors of serine proteases 1999 20 42 83%
Recent developments in the design of mechanism-based and alternate substrate inhibitors of serine proteases 2004 26 115 41%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ.
in class
1 IST TISIOL MALATTIE P 1 38% 0.4% 3
2 IST BIOSTRUTTURE GRP 1 100% 0.2% 2
3 SANOFI SYNTHE O GRP 1 50% 0.2% 2
4 ENZYMOL MOL FONCTIONNELLE 1 33% 0.4% 3
5 ETUD RECH CHIM ORGAN PL 1 50% 0.1% 1
6 MED P CRIT CARE OCCUPAT PULM MED 1 50% 0.1% 1
7 FR CNRS 1742UMR 7565 0 33% 0.1% 1
8 RECEPTOR ENZYME SCREENING TECHNOL 0 33% 0.1% 1
9 UNITE ANAL STRUCT 0 33% 0.1% 1
10 ENZYME MED CHEM 2 0 18% 0.2% 2

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000232678 ELAFIN//SLPI//SECRETORY LEUKOCYTE PROTEASE INHIBITOR
2 0.0000119129 ALLIED MED SCI SUMA KU//MED FUKUSHIMA KU//TARUMI KU
3 0.0000118659 KETOSTEROID ISOMERASE//LOW BARRIER HYDROGEN BONDS//LOW BARRIER HYDROGEN BOND
4 0.0000095861 ALKYLIDENE LACTONES//REACTIONS IN ALKALI//4 PENTYNOIC ACID
5 0.0000087731 PANICLE EXSERTION//ADDITIVE METHODS//EDUC FIELD SCI
6 0.0000084139 ISOTHIAZOLES//ISOTHIAZOLIUM SALTS//1 2 BENZISOTHIAZOL 32H ONE
7 0.0000080580 STAUDINGER REACTION//KINUGASA REACTION//AZETIDIN 2 ONES
8 0.0000077476 AMINOALKANESULFONIC ACID//BETA SULTAM//BETA SULTAMS
9 0.0000074197 AS 924//ORAL CEPHALOSPORIN//CEFCAPENE PIVOXIL
10 0.0000066542 AB INITIO QUANTUM MECHANICAL//NITROSTYRENE DERIVATIVES//SEMIEMPIRICAL QUANTUM MECHANICAL