Class information for:
Level 1: CYP2A6//CYP2A5//CYP2A13

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
12369 846 36.8 74%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
395 16247 CYTOCHROME P450//CYP2D6//PREGNANE X RECEPTOR

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 CYP2A6 Author keyword 77 54% 12% 100
2 CYP2A5 Author keyword 38 76% 3% 26
3 CYP2A13 Author keyword 27 78% 2% 18
4 COUMARIN 7 HYDROXYLATION Author keyword 21 90% 1% 9
5 NICOTINE METABOLISM Author keyword 16 51% 3% 22
6 COUMARIN 7 HYDROXYLASE Author keyword 15 73% 1% 11
7 CYTOCHROME P450 2A6 Author keyword 9 55% 1% 12
8 CYTOCHROME P450 2A5 Author keyword 9 83% 1% 5
9 7 HYDROXYCOUMARIN GLUCURONIDE Author keyword 6 80% 0% 4
10 NICOTINE METABOLITE RATIO Author keyword 6 80% 0% 4

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 CYP2A6 77 54% 12% 100 Search CYP2A6 Search CYP2A6
2 CYP2A5 38 76% 3% 26 Search CYP2A5 Search CYP2A5
3 CYP2A13 27 78% 2% 18 Search CYP2A13 Search CYP2A13
4 COUMARIN 7 HYDROXYLATION 21 90% 1% 9 Search COUMARIN+7+HYDROXYLATION Search COUMARIN+7+HYDROXYLATION
5 NICOTINE METABOLISM 16 51% 3% 22 Search NICOTINE+METABOLISM Search NICOTINE+METABOLISM
6 COUMARIN 7 HYDROXYLASE 15 73% 1% 11 Search COUMARIN+7+HYDROXYLASE Search COUMARIN+7+HYDROXYLASE
7 CYTOCHROME P450 2A6 9 55% 1% 12 Search CYTOCHROME+P450+2A6 Search CYTOCHROME+P450+2A6
8 CYTOCHROME P450 2A5 9 83% 1% 5 Search CYTOCHROME+P450+2A5 Search CYTOCHROME+P450+2A5
9 7 HYDROXYCOUMARIN GLUCURONIDE 6 80% 0% 4 Search 7+HYDROXYCOUMARIN+GLUCURONIDE Search 7+HYDROXYCOUMARIN+GLUCURONIDE
10 NICOTINE METABOLITE RATIO 6 80% 0% 4 Search NICOTINE+METABOLITE+RATIO Search NICOTINE+METABOLITE+RATIO

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 COUMARIN 7 HYDROXYLATION 139 78% 11% 92
2 C OXIDATION 101 71% 10% 82
3 CYTOCHROME P450 2A6 CYP2A6 80 90% 4% 35
4 CYTOCHROME P450 2A6 74 70% 7% 61
5 COUMARIN 7 HYDROXYLASE ACTIVITY 67 76% 6% 47
6 NICOTINE METABOLISM 55 45% 11% 93
7 COUMARIN 7 HYDROXYLASE 47 60% 6% 52
8 7 HYDROXYLASE ACTIVITY 42 94% 2% 15
9 CIS 3 5 DIMETHYL 2 3 PYRIDYLTHIAZOLIDIN 4 ONE HYDROCHLORIDE 32 88% 2% 15
10 CYP2A6 31 45% 6% 52

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Toxicology and risk assessment of coumarin: Focus on human data 2010 33 34 82%
Function and Regulation of the Cyp2a5/CYP2A6 Genes in Response to Toxic Insults in the Liver 2013 9 167 57%
Metabolism and disposition kinetics of nicotine 2005 530 375 26%
Genetic variability in CYP2A6 and the pharmacokinetics of nicotine 2007 47 118 69%
Genetic polymorphisms in the cytochrome P450 2A6 (CYP2A6) gene: Implications for interindividual differences in nicotine metabolism 2001 101 44 89%
Clinical pharmacology of nicotine: Implications for understanding, preventing, and treating tobacco addiction 2008 192 43 21%
Structure, Function, Regulation and Polymorphism of Human Cytochrome P450 2A6 2009 40 248 46%
Coumarin metabolism, toxicity and carcinogenicity: Relevance for human risk assessment 1999 187 144 59%
Systematic review of the relationship between the 3-hydroxycotinine/cotinine ratio and cigarette dependence 2011 9 35 77%
CYP2A6 polymorphisms and risk for tobacco-related cancers 2008 27 103 77%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 CLIN PHARMACOL EXPT THER EUT 4 14% 3.4% 29
2 PHARMACOBIODYNAM 2 19% 1.1% 9
3 PATHOL HOST DEF 2 11% 1.7% 14
4 PHARMACOL TOXICOL PSYCHIAT 1 31% 0.5% 4
5 CLIN PHARMACOL EXPT THER EUTMED SERV 1 38% 0.4% 3
6 TOXICOL BIOL MOL 1 38% 0.4% 3
7 RENNEBOHM HALL PHARM 1 100% 0.2% 2
8 SAN FRANCISCO GEN HOSPMED 1 40% 0.2% 2
9 DRUG METAB TOXICOL 1 19% 0.5% 4
10 PHARMACOBIODYNAMKITA KU 1 33% 0.2% 2

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000213496 OLFACTORY MUCOSA//BOWMANS GLANDS//BETA BETA IMINODIPROPIONITRILE IDPN
2 0.0000174647 COTININE//TRANS 3 HYDROXYCOTININE//NORCOTININE
3 0.0000157694 TOBACCO SPECIFIC N NITROSAMINES//NNK//NNAL
4 0.0000126015 PHARMACOKINET BIOANAL//CYP2D19//PROPRANOLOL ENANTIOMER
5 0.0000108581 CYP1B1//CYP2S1//CYTOCHROME P4501B1
6 0.0000105681 ESCULETIN//4 HYDROXYCOUMARIN//CALRETICULIN TRANSACETYLASE
7 0.0000101594 SITE OF METABOLISM//ACTIVE SITE TOPOLOGY//COMPUTAT CHEM MOL STRUCT
8 0.0000082016 DRD2//REWARD DEFICIENCY SYNDROME RDS//D2 DOPAMINE RECEPTOR GENE
9 0.0000080965 CYP2C12//ONE DAY TREATMENT//S BIOCHEM
10 0.0000080875 LIVER SLICES//PRECISION CUT TISSUE SLICES//PRECISION CUT LIVER SLICES