Class information for:
Level 1: BOF 4272//MULTIPLE INDICATOR DILUTION//HEPATIC ELIMINATION

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
12239 857 30.3 48%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
1987 5071 JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS//JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS//NONMEM

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 BOF 4272 Author keyword 18 89% 1% 8
2 MULTIPLE INDICATOR DILUTION Author keyword 4 33% 1% 11
3 HEPATIC ELIMINATION Author keyword 4 47% 1% 7
4 MULTIFILT Author keyword 4 75% 0% 3
5 SECT PHARMACOKINET Address 4 23% 2% 16
6 LOCAL DISPOSITION Author keyword 3 100% 0% 3
7 NARUTO DRUG METAB Address 3 100% 0% 3
8 STATISTICAL MOMENT ANALYSIS Author keyword 2 44% 0% 4
9 FRACTAL HETEROGENEITY Author keyword 2 67% 0% 2
10 NARUTO Address 2 18% 1% 9

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 BOF 4272 18 89% 1% 8 Search BOF+4272 Search BOF+4272
2 MULTIPLE INDICATOR DILUTION 4 33% 1% 11 Search MULTIPLE+INDICATOR+DILUTION Search MULTIPLE+INDICATOR+DILUTION
3 HEPATIC ELIMINATION 4 47% 1% 7 Search HEPATIC+ELIMINATION Search HEPATIC+ELIMINATION
4 MULTIFILT 4 75% 0% 3 Search MULTIFILT Search MULTIFILT
5 LOCAL DISPOSITION 3 100% 0% 3 Search LOCAL+DISPOSITION Search LOCAL+DISPOSITION
6 STATISTICAL MOMENT ANALYSIS 2 44% 0% 4 Search STATISTICAL+MOMENT+ANALYSIS Search STATISTICAL+MOMENT+ANALYSIS
7 FRACTAL HETEROGENEITY 2 67% 0% 2 Search FRACTAL+HETEROGENEITY Search FRACTAL+HETEROGENEITY
8 2 COMPARTMENT DISPERSION MODEL 1 100% 0% 2 Search 2+COMPARTMENT+DISPERSION+MODEL Search 2+COMPARTMENT+DISPERSION+MODEL
9 DIFFUSIONAL BARRIER 1 50% 0% 2 Search DIFFUSIONAL+BARRIER Search DIFFUSIONAL+BARRIER
10 ENALAPRIL AND ENALAPRILAT 1 50% 0% 2 Search ENALAPRIL+AND+ENALAPRILAT Search ENALAPRIL+AND+ENALAPRILAT

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 MULTIPLE INDICATOR DILUTION 55 70% 5% 45
2 LOCAL DISPOSITION 41 90% 2% 18
3 2 COMPARTMENT DISPERSION MODEL 27 76% 2% 19
4 HEPATIC ELIMINATION 21 48% 4% 32
5 GENTISAMIDE 17 100% 1% 8
6 RESIDENCE TIME DISTRIBUTIONS 15 38% 4% 31
7 CYTOPLASMIC BINDING 11 69% 1% 9
8 DIFFUSIONAL BARRIER 9 50% 2% 13
9 DISPERSION MODEL 7 16% 5% 42
10 HEPATIC DRUG ELIMINATION 7 67% 1% 6

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Application of a convective-dispersion model to predict in vivo hepatic clearance from in vitro measurements utilizing cryopreserved human hepatocytes 2003 10 11 73%
CLEARANCE APPROACHES IN PHARMACOLOGY 1987 311 231 24%
MODELS OF HEPATIC DRUG ELIMINATION 1992 26 19 74%
Formed and preformed metabolites: facts and comparisons 2008 14 197 26%
Safety testing of metabolites: Expectations and outcomes 2009 10 101 31%
PBPK Modeling of Intestinal and Liver Enzymes and Transporters in Drug Absorption and Sequential Metabolism 2010 20 191 14%
DETERMINANTS OF METABOLITE DISPOSITION 1992 13 84 62%
Loading-washout studies of the stereoselective sinusoidal uptake of (R)and (S)-2-phenylpropionyl acyl glucuronide 2006 0 17 53%
The multiple indicator dilution method and its utility in risk assessment 2000 5 73 40%
Effect of hypoxia on cytochrome P450 activity and expression 2004 48 133 13%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 SECT PHARMACOKINET 4 23% 1.9% 16
2 NARUTO DRUG METAB 3 100% 0.4% 3
3 NARUTO 2 18% 1.1% 9
4 PLATEAU ENVIRONM DAMAGE CONTROL 1 33% 0.2% 2
5 ADV SCI TECHNOL BIOACT MAT 1 50% 0.1% 1
6 BIOPHYS PHYSICOCHEM 1 50% 0.1% 1
7 CJF 91 07 1 50% 0.1% 1
8 PHARMACOGENET MOL TOXICOL 1 50% 0.1% 1
9 SIGNALISAT DIFFERENCIAT MACROPHAGES 1 50% 0.1% 1
10 PHYS EXPT ONCOL 0 33% 0.1% 1

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000158691 MED HOSP PHARM YAHATANISHI KU//4 HYDROXYPROPRANOLOL//PROPRANOLOL METABOLISM
2 0.0000139188 JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS//DISTRIBUTION CLEARANCE//CURVE MOMENTS
3 0.0000136297 INTERSPECIES SCALING//DMPK TRANSLAT SCI//WELL STIRRED MODEL
4 0.0000112855 CONGENITAL CHLORIDE DIARRHEA//SLC26A3//NASI 1
5 0.0000106670 K M AND V MAX//PERFUSED MOUSE LIVER//N DESMETHYLDIAZEPAM
6 0.0000103509 BILITRANSLOCASE//CANALICULAR MEMBRANE//HEPATOCYTE COUPLETS
7 0.0000099939 METABOLIC ZONATION//BIVASCULAR LIVER PERFUSION//CARBAMOYLPHOSPHATE SYNTHETASE I
8 0.0000082486 MONOETHYLGLYCINEXYLIDIDE//MEGX//C 13 METHACETIN
9 0.0000082227 TRIMELAMOL//HEXAMETHYLMELAMINE//DEHYDROEMETINE
10 0.0000076527 INO 2628 CZ//DOUBLE PEAKS//DISCONTINUOUS ABSORPTION