Class information for:
Level 1: BONE TARGETING//OSTEOTROPIC DRUG DELIVERY SYSTEM//FARNESYL PYROPHOSPHATE SYNTHASE

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
11818 888 29.7 66%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
1423 7465 BISPHOSPHONATES//ZOLEDRONIC ACID//BISPHOSPHONATE

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 BONE TARGETING Author keyword 25 51% 4% 35
2 OSTEOTROPIC DRUG DELIVERY SYSTEM Author keyword 14 100% 1% 7
3 FARNESYL PYROPHOSPHATE SYNTHASE Author keyword 10 42% 2% 18
4 UMYMFOR CONICET FCEYN Address 9 64% 1% 9
5 CHIM STRUCT BIOMOL Address 9 45% 2% 15
6 BISPHOSPHONIC ACID Author keyword 7 64% 1% 7
7 GEM BISPHOSPHONATES Author keyword 6 71% 1% 5
8 AMINO ACID BIOSYNTHESIS INHIBITORS AS HERBICIDES Author keyword 6 100% 0% 4
9 GEM BISPHOSPHONATE Author keyword 6 100% 0% 4
10 HYDROXYAPATITE AFFINITY Author keyword 6 100% 0% 4

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 BONE TARGETING 25 51% 4% 35 Search BONE+TARGETING Search BONE+TARGETING
2 OSTEOTROPIC DRUG DELIVERY SYSTEM 14 100% 1% 7 Search OSTEOTROPIC+DRUG+DELIVERY+SYSTEM Search OSTEOTROPIC+DRUG+DELIVERY+SYSTEM
3 FARNESYL PYROPHOSPHATE SYNTHASE 10 42% 2% 18 Search FARNESYL+PYROPHOSPHATE+SYNTHASE Search FARNESYL+PYROPHOSPHATE+SYNTHASE
4 BISPHOSPHONIC ACID 7 64% 1% 7 Search BISPHOSPHONIC+ACID Search BISPHOSPHONIC+ACID
5 GEM BISPHOSPHONATES 6 71% 1% 5 Search GEM+BISPHOSPHONATES Search GEM+BISPHOSPHONATES
6 AMINO ACID BIOSYNTHESIS INHIBITORS AS HERBICIDES 6 100% 0% 4 Search AMINO+ACID+BIOSYNTHESIS+INHIBITORS+AS+HERBICIDES Search AMINO+ACID+BIOSYNTHESIS+INHIBITORS+AS+HERBICIDES
7 GEM BISPHOSPHONATE 6 100% 0% 4 Search GEM+BISPHOSPHONATE Search GEM+BISPHOSPHONATE
8 HYDROXYAPATITE AFFINITY 6 100% 0% 4 Search HYDROXYAPATITE+AFFINITY Search HYDROXYAPATITE+AFFINITY
9 BISPHOSPHONIC ACIDS 5 50% 1% 7 Search BISPHOSPHONIC+ACIDS Search BISPHOSPHONIC+ACIDS
10 ACIDIC OLIGOPEPTIDE 4 75% 0% 3 Search ACIDIC+OLIGOPEPTIDE Search ACIDIC+OLIGOPEPTIDE

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 FARNESYL PYROPHOSPHATE SYNTHASE 31 45% 6% 53
2 AMINOMETHANE 1 1 DIPHOSPHONIC ACIDS 23 100% 1% 10
3 BIOREVERSIBLE PRODRUGS 21 90% 1% 9
4 NITROGEN CONTAINING BISPHOSPHONATES 21 18% 12% 104
5 1 PHENYL 1 HYDROXYMETHYLENE BISPHOSPHONATE 20 100% 1% 9
6 BISPHOSPHONATE PRODRUGS 19 70% 2% 16
7 HETEROCYCLIC DRONIC ACIDS 18 89% 1% 8
8 BONE AFFINITY 14 100% 1% 7
9 ANTIRESORPTIVE PROPERTIES 12 86% 1% 6
10 PYROPHOSPHATE SYNTHASE 9 27% 3% 30

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
The relationship between the chemistry and biological activity of the bisphosphonates 2011 75 79 44%
Bisphosphonates: therapeutics potential and recent advances in drug delivery 2015 2 53 21%
Bisphosphonates: The first 40 years 2011 194 163 11%
"Greener" synthesis of bisphosphonic/dronic acid derivatives 2014 1 13 92%
N-Heterocyclic Dronic Acids: Applications and Synthesis 2012 11 98 57%
Biomedical applications of bisphosphonates 2013 24 170 15%
Systemic Drug Delivery Systems for Bone Tissue Regeneration- A Mini Review 2015 1 58 24%
Molecular Targets of the Nitrogen Containing Bisphosphonates: The Molecular Pharmacology of Prenyl Synthase Inhibition 2010 21 85 47%
Targeting Isoprenoid Biosynthesis for Drug Discovery: Bench to Bedside 2010 53 51 22%
Bone-specific drug delivery systems - Approaches via chemical modification of bone-seeking agents 2003 55 53 49%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 UMYMFOR CONICET FCEYN 9 64% 1.0% 9
2 CHIM STRUCT BIOMOL 9 45% 1.7% 15
3 CHIM HETERO ORGAN 4 67% 0.5% 4
4 URA 1430 CNRS 3 100% 0.3% 3
5 FISIOPATOL ORTOPED MED RIGENERAT 3 50% 0.5% 4
6 CHIM HETEROORGAN 3 60% 0.3% 3
7 MUSCULOSKELETAL SCINUFFIELD ORTHOPAED 2 67% 0.2% 2
8 UMR 7033UFR SMBH 2 67% 0.2% 2
9 FEED QUAL INSPECT 1 100% 0.2% 2
10 LOPEZ NEYRA PARASITOL BIOMED 1 50% 0.2% 2

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000199929 CONTAMINAT CONTROL//WIPERS//NMR CONTRAST AGENT
2 0.0000155298 DIFLUOROMETHYLENEPHOSPHONATES//DIFLUOROPHOSPHONATE//PHOSPHATE MIMICS
3 0.0000124665 ALENDRONATE SODIUM//1 NAPHTHYLISOTHIOCYANATE//OLPADRONATE
4 0.0000124511 BRONJ//OSTEONECROSIS OF THE JAW//ONJ
5 0.0000105013 ZOLEDRONIC ACID//SKELETAL RELATED EVENTS//BONE METASTASES
6 0.0000101975 O ETHYL THIOCARBOXYLATES//ORGANOPHOSPHORUS CPDS//2 AZAALLYL ANIONS
7 0.0000089032 RHENIUM 186 HEDP//BONE PAIN PALLIATION//STRONTIUM 89
8 0.0000081411 AMINOPHOSPHONATE LIGAND//CIS PTII COMPLEX OF 3 AMINOFLAVONE//CIS BIS3 AMINOFLAVONEDICHLOROPLATINUMII
9 0.0000079674 ALPHA AMINO PHOSPHONATES//ALPHA AMINOPHOSPHONATE//AMINOPHOSPHONIC ACIDS
10 0.0000078318 HYDROPHOSPHINYLATION//VINYLPHOSPHONATES//ARYLPHOSPHONATES