Class information for:
Level 1: EZETIMIBE//CHOLESTEROL ABSORPTION INHIBITOR//COLESEVELAM

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
11704 897 39.8 83%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
408 16067 STATINS//EZETIMIBE//SIMVASTATIN

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 EZETIMIBE Author keyword 204 46% 37% 329
2 CHOLESTEROL ABSORPTION INHIBITOR Author keyword 26 61% 3% 27
3 COLESEVELAM Author keyword 22 53% 3% 29
4 NPC1L1 Author keyword 22 45% 4% 36
5 COLESEVELAM HCL Author keyword 16 61% 2% 17
6 BILE ACID SEQUESTRANT Author keyword 14 40% 3% 27
7 NIEMANN PICK C1 LIKE 1 Author keyword 14 55% 2% 17
8 COLESEVELAM HYDROCHLORIDE Author keyword 8 100% 1% 5
9 CHOLESTEROL ABSORPTION Author keyword 8 16% 5% 45
10 BILE ACID SEQUESTRANTS Author keyword 7 33% 2% 17

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 EZETIMIBE 204 46% 37% 329 Search EZETIMIBE Search EZETIMIBE
2 CHOLESTEROL ABSORPTION INHIBITOR 26 61% 3% 27 Search CHOLESTEROL+ABSORPTION+INHIBITOR Search CHOLESTEROL+ABSORPTION+INHIBITOR
3 COLESEVELAM 22 53% 3% 29 Search COLESEVELAM Search COLESEVELAM
4 NPC1L1 22 45% 4% 36 Search NPC1L1 Search NPC1L1
5 COLESEVELAM HCL 16 61% 2% 17 Search COLESEVELAM+HCL Search COLESEVELAM+HCL
6 BILE ACID SEQUESTRANT 14 40% 3% 27 Search BILE+ACID+SEQUESTRANT Search BILE+ACID+SEQUESTRANT
7 NIEMANN PICK C1 LIKE 1 14 55% 2% 17 Search NIEMANN+PICK+C1+LIKE+1 Search NIEMANN+PICK+C1+LIKE+1
8 COLESEVELAM HYDROCHLORIDE 8 100% 1% 5 Search COLESEVELAM+HYDROCHLORIDE Search COLESEVELAM+HYDROCHLORIDE
9 CHOLESTEROL ABSORPTION 8 16% 5% 45 Search CHOLESTEROL+ABSORPTION Search CHOLESTEROL+ABSORPTION
10 BILE ACID SEQUESTRANTS 7 33% 2% 17 Search BILE+ACID+SEQUESTRANTS Search BILE+ACID+SEQUESTRANTS

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 PRIMARY HYPERCHOLESTEROLEMIA 93 37% 23% 203
2 CHOLESTEROL ABSORPTION INHIBITOR 84 54% 12% 107
3 SCH58235 67 85% 4% 35
4 LIPID ALTERING EFFICACY 54 71% 5% 44
5 ABSORPTION INHIBITOR 54 72% 5% 43
6 EZETIMIBE 45 29% 15% 131
7 NPC1L1 39 55% 5% 49
8 C GOAL ATTAINMENT 31 92% 1% 12
9 ATORVASTATIN 20 MG 27 92% 1% 11
10 INTESTINAL CHOLESTEROL ABSORPTION 26 40% 6% 50

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Lipid-altering efficacy of ezetimibe plus statin and statin monotherapy and identification of factors associated with treatment response: A pooled analysis of over 21,000 subjects from 27 clinical trials 2012 29 60 62%
Effectiveness of Combination Therapy With Statin and Another Lipid-Modifying Agent Compared With Intensified Statin Monotherapy A Systematic Review 2014 12 62 50%
Comparative efficacy of the addition of ezetimibe to statin vs statin titration in patients with hypercholesterolaemia: systematic review and meta-analysis 2011 27 34 74%
Niemann-Pick C1-Like 1 (NPC1L1) Protein in Intestinal and Hepatic Cholesterol Transport 2011 44 131 50%
Zetia: Inhibition of Niemann-Pick C1 like 1 (NPC1L1) to reduce intestinal cholesterol absorption and treat hyperlipidemia 2007 84 42 88%
Niemann-Pick C1 Like 1 (NPC1L1) an intestinal sterol transporter 2009 52 38 71%
NPC1L1 and cholesterol transport 2010 37 86 62%
Ezetimibe - A review of its metabolism, pharmacokinetics and drug interactions 2005 185 44 50%
Ezetimibe and bile acid sequestrants: impact on lipoprotein metabolism and beyond 2013 8 55 53%
Safety evaluation of colesevelam therapy to achieve glycemic and lipid goals in type 2 diabetes 2011 5 8 100%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 EARLY CLIN EXPT MED 5 54% 0.8% 7
2 FEDERAT PUBL SERV PERSONNEL MUTUAL ASSOC 2 50% 0.3% 3
3 SECT LIPID SCI 2 13% 1.6% 14
4 POINT MED 2 24% 0.7% 6
5 MARIE CURIE TRAINING CARDIOVASC DIS 1 50% 0.2% 2
6 N ESTONIA REG HOSP 1 50% 0.2% 2
7 RECH CLIN POLYCLIN 1 100% 0.2% 2
8 CLIN QUANTITAT SCI 1 23% 0.3% 3
9 GLOBAL SCI MED PUBLICAT 1 17% 0.4% 4
10 AMC TYTGAT 1 50% 0.1% 1

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000189767 PLANT STEROLS//PHYTOSTEROLS//SITOSTANOL
2 0.0000174480 STATINS//LOW DENSITY LIPOPROTEIN CHOLESTEROL//ATORVASTATIN
3 0.0000140867 ROSUVASTATIN CALCIUM//ATORVASTATIN CALCIUM//EZETIMIBE GLUCURONIDE
4 0.0000119528 NK 104//PITAVASTATIN//CAS 147526 32 7
5 0.0000112298 STATIN MYOPATHY//STATIN INTOLERANCE//MYALGIA
6 0.0000098393 LAROPIPRANT//NIACIN//HM74A
7 0.0000095232 FENOFIBRIC ACID//FENOFIBRATE//FIBRATES
8 0.0000092076 PCSK9//PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9//MIPOMERSEN
9 0.0000077732 DMP 504//POLYCATIONIC SALTS//SEQUESTRANTS
10 0.0000068866 LIPOPROT UNIT//LIPOPROTEIN KINETICS//OURCE IL KINET ANAL