Class information for:
Level 1: ROLLINS 5119//ANTIPYRINE PHARMACOKINETICS//CYTOCHROME P4502B1 2

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
11620 902 37.9 66%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
395 16247 CYTOCHROME P450//CYP2D6//PREGNANE X RECEPTOR

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ.
in class
1 ROLLINS 5119 Address 4 75% 0% 3
2 ANTIPYRINE PHARMACOKINETICS Author keyword 2 67% 0% 2
3 CYTOCHROME P4502B1 2 Author keyword 2 67% 0% 2
4 PHYSIOL PHARM CLIN Address 2 67% 0% 2
5 9000 X G SUPERNATANT Author keyword 1 100% 0% 2
6 CYTOCHROME P450 INFLAMMATION Author keyword 1 100% 0% 2
7 IMMUNOPHYSIOL GEN COMPAREE Address 1 50% 0% 2
8 PHARMACOINFORMAT MED UNIT Address 1 100% 0% 2
9 REGULATORY STRATEGY Address 1 50% 0% 2
10 CANC PHARMACOL UNIT Address 1 23% 1% 5

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ.
in class		 LCSH search Wikipedia search
1 ANTIPYRINE PHARMACOKINETICS 2 67% 0% 2 Search ANTIPYRINE+PHARMACOKINETICS Search ANTIPYRINE+PHARMACOKINETICS
2 CYTOCHROME P4502B1 2 2 67% 0% 2 Search CYTOCHROME+P4502B1+2 Search CYTOCHROME+P4502B1+2
3 9000 X G SUPERNATANT 1 100% 0% 2 Search 9000+X+G+SUPERNATANT Search 9000+X+G+SUPERNATANT
4 CYTOCHROME P450 INFLAMMATION 1 100% 0% 2 Search CYTOCHROME+P450+INFLAMMATION Search CYTOCHROME+P450+INFLAMMATION
5 HEPATIC DRUG METABOLISM 1 27% 0% 3 Search HEPATIC+DRUG+METABOLISM Search HEPATIC+DRUG+METABOLISM
6 CYP3A2 1 15% 1% 6 Search CYP3A2 Search CYP3A2
7 ADULT RAT HEPATOCYTE 1 50% 0% 1 Search ADULT+RAT+HEPATOCYTE Search ADULT+RAT+HEPATOCYTE
8 BIO THERAPEUTICS 1 50% 0% 1 Search BIO+THERAPEUTICS Search BIO+THERAPEUTICS
9 CYTOCHROME P450 3A2 CYP3A2 1 50% 0% 1 Search CYTOCHROME+P450+3A2+CYP3A2 Search CYTOCHROME+P450+3A2+CYP3A2
10 DB PLUS MICE 1 50% 0% 1 Search DB++PLUS+MICE Search DB++PLUS+MICE

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 INTERFERON MEDIATED DEPRESSION 21 90% 1% 9
2 CYTOCHROME P 450 GENE EXPRESSION 11 54% 2% 14
3 POLYRIBOINOSINIC ACID 9 83% 1% 5
4 LIVER DRUG METABOLISM 8 70% 1% 7
5 INTERFERON INDUCING AGENTS 6 71% 1% 5
6 ACID POLYRIBOCYTIDYLIC ACID 6 100% 0% 4
7 ASEPTIC INFLAMMATION 6 100% 0% 4
8 HEPATIC CYTOCHROME P450 5 15% 3% 27
9 CYTOCHROME P450 GENE REGULATION 4 75% 0% 3
10 CYTOCHROME P450 REGULATION 4 75% 0% 3

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Critical Review of Preclinical Approaches to Investigate Cytochrome P450-Mediated Therapeutic Protein Drug-Drug Interactions and Recommendations for Best Practices: A White Paper 2013 7 57 74%
Regulation of cytochrome P450 by inflammatory mediators: Why and how? 2001 215 56 48%
Regulation of drug-metabolizing enzymes and transporters in inflammation 2006 154 150 35%
Cytochrome P450 regulation and drug biotransformation during inflammation and infection 2004 80 109 65%
CYP-Mediated Therapeutic Protein-Drug Interactions Clinical Findings, Proposed Mechanisms and Regulatory Implications 2010 27 42 67%
Regulation of cytochromes P450 during inflammation and infection 1997 282 239 51%
Alteration of drug biotransformation and elimination during infection and inflammation 2001 108 181 70%
Can vaccines interact with drug metabolism? 2015 1 53 58%
Inflammatory response: an unrecognised source of variability in the pharmacokinetics and pharmacodynamics of cancer chemotherapy 2003 102 58 29%
Mechanisms of Monoclonal Antibody-Drug Interactions 2011 14 52 56%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ.
in class
1 ROLLINS 5119 4 75% 0.3% 3
2 PHYSIOL PHARM CLIN 2 67% 0.2% 2
3 IMMUNOPHYSIOL GEN COMPAREE 1 50% 0.2% 2
4 PHARMACOINFORMAT MED UNIT 1 100% 0.2% 2
5 REGULATORY STRATEGY 1 50% 0.2% 2
6 CANC PHARMACOL UNIT 1 23% 0.6% 5
7 PHARM PHAMACOKINET 1 40% 0.2% 2
8 SAFETY ASSESSMENT TRADIT CHINESE MED 1 27% 0.3% 3
9 CENTOCOR RD 1 50% 0.1% 1
10 CLIN PHARMACOL EARLY DEV 1 50% 0.1% 1

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000102102 TRIMETHADIONE//ZAKLAD CHEM FIZJOL//ZAKLAD CHEM FIZJOLOGICZNEJ
2 0.0000075936 BURSAL DISEASE VIRUS BDV//VIRUS VACCINE THERAPY//DECOMPENSATED HEPATITIS
3 0.0000074232 PREGNANE X RECEPTOR//PXR//CONSTITUTIVE ANDROSTANE RECEPTOR
4 0.0000072384 CYP2C12//ONE DAY TREATMENT//S BIOCHEM
5 0.0000072214 DICROCOELIUM DENDRITICUM//SISTEMAS PROD SANIDAD ANIM//DICROCOELIUM CHINENSIS
6 0.0000069728 ALPHA NAPHTHYLISOTHIOCYANATE//IDIOSYNCRATIC DRUG INDUCED LIVER INJURY//IDIOSYNCRATIC ADVERSE DRUG REACTIONS
7 0.0000064723 ASAN FDN//DA 125//MED DIAGNOST PATHOL
8 0.0000059690 MARIE LOWE COMPARAT ONCOL//CYP2D//MARI LOWE COMPARAT ONCOL
9 0.0000054575 SERUM MEDIATORS//LY2216684//NEPHROLOGY CLINICAL PRACTICE GUIDELINES
10 0.0000053246 LIVER CARCINOGEN METABOLIZING ENZYMES//ARYL HYDROCARBON HYDROXYLASE//DEMETHYLASES