Class information for:
Level 1: NNRTIS//REVERSE TRANSCRIPTASE//HIV 1 REVERSE TRANSCRIPTASE

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
1128 2738 39.3 82%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
26 34435 ANTIRETROVIRAL THERAPY//HIV//NEVIRAPINE

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 NNRTIS Author keyword 106 59% 4% 119
2 REVERSE TRANSCRIPTASE Author keyword 93 24% 12% 332
3 HIV 1 REVERSE TRANSCRIPTASE Author keyword 57 48% 3% 86
4 NNRTI Author keyword 46 44% 3% 79
5 HEPT Author keyword 31 71% 1% 25
6 HIV DRUG ISTANCE PROGRAM Address 31 22% 5% 126
7 TIBO Author keyword 23 72% 1% 18
8 S DABOS Author keyword 21 90% 0% 9
9 MOL INTERACT GRP Address 21 85% 0% 11
10 HIV 1 RT Author keyword 19 51% 1% 26

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 NNRTIS 106 59% 4% 119 Search NNRTIS Search NNRTIS
2 REVERSE TRANSCRIPTASE 93 24% 12% 332 Search REVERSE+TRANSCRIPTASE Search REVERSE+TRANSCRIPTASE
3 HIV 1 REVERSE TRANSCRIPTASE 57 48% 3% 86 Search HIV+1+REVERSE+TRANSCRIPTASE Search HIV+1+REVERSE+TRANSCRIPTASE
4 NNRTI 46 44% 3% 79 Search NNRTI Search NNRTI
5 HEPT 31 71% 1% 25 Search HEPT Search HEPT
6 TIBO 23 72% 1% 18 Search TIBO Search TIBO
7 S DABOS 21 90% 0% 9 Search S+DABOS Search S+DABOS
8 HIV 1 RT 19 51% 1% 26 Search HIV+1+RT Search HIV+1+RT
9 TSAO T 17 100% 0% 8 Search TSAO+T Search TSAO+T
10 RNASE H 16 25% 2% 57 Search RNASE+H Search RNASE+H

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 NONNUCLEOSIDE INHIBITORS 371 54% 18% 483
2 NNRTIS 139 80% 3% 87
3 SEQUENCE FEATURES IMPORTANT 94 97% 1% 28
4 ANTI HIV 1 ACTIVITY 85 41% 6% 162
5 POSITIONAL ADAPTABILITY 79 82% 2% 46
6 EFAVIRENZ DMP 266 77 96% 1% 24
7 TIBO DERIVATIVES 74 69% 2% 63
8 RIBONUCLEASE H 63 32% 6% 162
9 TEMPLATE PRIMER 62 57% 3% 73
10 1 2 HYDROXYETHOXYMETHYL 6 PHENYLTHIOTHYMINE 58 66% 2% 53

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Structure and Function of HIV-1 Reverse Transcriptase: Molecular Mechanisms of Polymerization and Inhibition 2009 134 155 68%
A review on recent developments of indole-containing antiviral agents 2015 8 116 17%
Non-nucleoside reverse transcriptase inhibitors (NNRTIs), their discovery, development, and use in the treatment of HIV-1 infection: A review of the last 20 years (1989-2009) 2010 134 166 54%
Non-nucleoside reverse transcriptase inhibitors (NNRTIs): Past, present, and future 2004 147 134 84%
Molecular basis of human immunodeficiency virus type 1 drug resistance: Overview and recent developments 2013 36 325 33%
Crystallography and the design of anti-AIDS drugs: Conformational flexibility and positional adaptability are important in the design of non-nucleoside HIV-1 reverse transcriptase inhibitors 2005 138 55 73%
Human Immunodeficiency Virus Reverse Transcriptase: 25 Years of Research, Drug Discovery, and Promise 2012 18 85 72%
LOCATIONS OF ANTI-AIDS DRUG-BINDING SITES AND RESISTANCE MUTATIONS IN THE 3-DIMENSIONAL STRUCTURE OF HIV-1 REVERSE-TRANSCRIPTASE - IMPLICATIONS FOR MECHANISMS OF DRUG-INHIBITION AND RESISTANCE 1994 384 74 72%
RNase H activity: Structure, specificity, and function in reverse transcription 2008 49 152 85%
Current status of the non-nucleoside reverse transcriptase inhibitors of human immunodeficiency virus type 1 2004 98 190 78%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 HIV DRUG ISTANCE PROGRAM 31 22% 4.6% 126
2 MOL INTERACT GRP 21 85% 0.4% 11
3 RT BIOCHEM SECT 13 58% 0.5% 15
4 ISTANCE MECH 11 65% 0.4% 11
5 VIROL DRUG DISCOVERY 11 100% 0.2% 6
6 HIV DRUG ISTANCE PROGRAMNIH 8 100% 0.2% 5
7 REVERSE TRANSCRIPTASE BIOCHEM SECT 7 64% 0.3% 7
8 SEZ MICROBIOL VIROL GEN BIOTECNOL MICROB 6 47% 0.3% 9
9 ISTANCE MECHANISMS 6 100% 0.1% 4
10 SURG ONCOL IL 5 60% 0.2% 6

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000182774 ETRAVIRINE//RILPIVIRINE//TMC125
2 0.0000139860 K65R//TRANSMITTED DRUG RESISTANCE//HIV 1 DRUG RESISTANCE
3 0.0000115967 RNA DIMERIZATION//NCP7//HIV 1 NUCLEOCAPSID PROTEIN
4 0.0000085822 PYRAZOLOTHIADIAZINES//HIV 1NNRTIS//ELEMENTORGAN CHEM
5 0.0000075723 AICARDI GOUTIERES SYNDROME//TREX1//RIBONUCLEASE H
6 0.0000071083 DNA POLYMERASE//DNA POLYMERASE BETA//DNA POLYMERASE LAMBDA
7 0.0000068168 AREA TER IA CELULAR//SECC MODELIZAC MOL//SECC SINTESIS
8 0.0000065436 DIPARTIMENTO AGROCHIM AGROBIOL//DR ISOTHERM//LAGERGREN RATE EQUATION
9 0.0000058485 RT ASSAY//VIRUS FILTRATION//VIRAL CLEARANCE
10 0.0000057359 HIV 1 INTEGRASE//INTEGRASE//RALTEGRAVIR