Class information for:
Level 1: LEBER CONGENITAL AMAUROSIS//RPE65//CNGB3

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
10170 1022 43.2 85%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
334 17318 RETINITIS PIGMENTOSA//RETINAL DEGENERATION//RETINA

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 LEBER CONGENITAL AMAUROSIS Author keyword 28 46% 4% 45
2 RPE65 Author keyword 22 41% 4% 41
3 CNGB3 Author keyword 21 90% 1% 9
4 LEBERS CONGENITAL AMAUROSIS Author keyword 17 62% 2% 18
5 ACHROMATOPSIA Author keyword 12 34% 3% 30
6 MCGILL OCULAR GENET Address 12 39% 2% 24
7 OCULAR GENE THERAPY Author keyword 12 86% 1% 6
8 EIE EYE Address 11 12% 9% 92
9 RETINAL GENE THERAPY Author keyword 10 73% 1% 8
10 DAY BLINDNESS Author keyword 9 83% 0% 5

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 LEBER CONGENITAL AMAUROSIS 28 46% 4% 45 Search LEBER+CONGENITAL+AMAUROSIS Search LEBER+CONGENITAL+AMAUROSIS
2 RPE65 22 41% 4% 41 Search RPE65 Search RPE65
3 CNGB3 21 90% 1% 9 Search CNGB3 Search CNGB3
4 LEBERS CONGENITAL AMAUROSIS 17 62% 2% 18 Search LEBERS+CONGENITAL+AMAUROSIS Search LEBERS+CONGENITAL+AMAUROSIS
5 ACHROMATOPSIA 12 34% 3% 30 Search ACHROMATOPSIA Search ACHROMATOPSIA
6 OCULAR GENE THERAPY 12 86% 1% 6 Search OCULAR+GENE+THERAPY Search OCULAR+GENE+THERAPY
7 RETINAL GENE THERAPY 10 73% 1% 8 Search RETINAL+GENE+THERAPY Search RETINAL+GENE+THERAPY
8 DAY BLINDNESS 9 83% 0% 5 Search DAY+BLINDNESS Search DAY+BLINDNESS
9 CNGA3 9 67% 1% 8 Search CNGA3 Search CNGA3
10 SUBRETINAL INJECTION 7 53% 1% 9 Search SUBRETINAL+INJECTION Search SUBRETINAL+INJECTION

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 TOTAL COLOURBLINDNESS 62 74% 5% 46
2 LEBER CONGENITAL AMAUROSIS 61 26% 20% 201
3 SEVERE RETINAL DYSTROPHY 55 87% 3% 27
4 RESTORES VISION 52 87% 3% 26
5 RPE65 MUTATIONS 52 64% 5% 51
6 CONGENITAL ACHROMATOPSIA 45 90% 2% 19
7 CHILDHOOD BLINDNESS 37 31% 10% 100
8 AUTOSOMAL RECESSIVE ACHROMATOPSIA 34 93% 1% 13
9 GNAT2 34 93% 1% 13
10 OCULAR SUBRETINAL INJECTION 29 75% 2% 21

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
A Comprehensive Review of Retinal Gene Therapy 2013 41 184 40%
Gene therapy for Leber congenital amaurosis: advances and future directions 2012 20 65 91%
Novel adeno-associated viral vectors for retinal gene therapy 2012 34 80 60%
Gene Therapy of Inherited Retinal Degenerations: Prospects and Challenges 2015 2 95 53%
Gene supplementation therapy for recessive forms of inherited retinal dystrophies 2012 20 100 68%
Lighting a candle in the dark: advances in genetics and gene therapy of recessive retinal dystrophies 2010 63 130 42%
Advancing Therapeutic Strategies for Inherited Retinal Degeneration: Recommendations From the Monaciano Symposium 2015 3 117 26%
Gene Therapy of Inherited Retinopathies: A Long and Successful Road from Viral Vectors to Patients 2012 17 155 62%
Gene therapy progress and prospects: the eye 2006 79 50 50%
Gene therapy for ocular diseases 2011 24 99 51%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 MCGILL OCULAR GENET 12 39% 2.3% 24
2 EIE EYE 11 12% 9.0% 92
3 STELLAR CHANCE S 310 5 63% 0.5% 5
4 FM KIRBY MOL OPHTHALMOL 4 15% 2.5% 26
5 RECH THER EUT 1 3 57% 0.4% 4
6 KIRBY MOL OPHTHALMOL 3 50% 0.4% 4
7 MICROARRAY IL TUEBINGEN 3 60% 0.3% 3
8 MOL GENET OR 3 60% 0.3% 3
9 PEDIAT OPHTHALMOL OPHTHALMOGENET 3 60% 0.3% 3
10 UMR U649 3 60% 0.3% 3

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000257126 RETINITIS PIGMENTOSA//PERIPHERIN RDS//AUTOSOMAL DOMINANT RETINITIS PIGMENTOSA
2 0.0000196487 VISUAL CYCLE//ISOMEROHYDROLASE//FUNDUS ALBIPUNCTATUS
3 0.0000191806 PROGRESSIVE RETINAL ATROPHY//PROGRESSIVE ROD CONE DEGENERATION//GENERALISED PROGRESSIVE RETINAL ATROPHY
4 0.0000189950 RPGR//X LINKED RETINITIS PIGMENTOSA//RP2
5 0.0000134263 FREQUENIN//UNIT REGULATORY MOL BIOL//NCS 1
6 0.0000125028 ADENO ASSOCIATED VIRUS//AAV//POWELL GENE THER Y
7 0.0000115377 ALSTROM SYNDROME//ALMS1//TUBBY
8 0.0000110545 ABCA4//STARGARDT DISEASE//A2E
9 0.0000095955 CHOROIDEREMIA//POU3F4//DFN3
10 0.0000091538 RETINAL TRANSPLANTATION//SUBRETINAL TRANSPLANTATION//RETINAL TRANSPLANTS