Class information for:
Level 1: CRTH2//MOL BEHAV BIOL//PROSTAGLANDIN D 2

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
10081 1030 35.6 78%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
670 12541 CYCLOOXYGENASE 2//COX 2//CYCLOOXYGENASE

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 CRTH2 Author keyword 90 72% 7% 70
2 MOL BEHAV BIOL Address 76 47% 12% 119
3 PROSTAGLANDIN D 2 Author keyword 52 38% 10% 108
4 DP RECEPTOR Author keyword 39 80% 2% 24
5 LIPOCALIN TYPE PROSTAGLANDIN D SYNTHASE Author keyword 35 76% 2% 25
6 PROSTAGLANDIN D SYNTHASE Author keyword 30 55% 4% 37
7 PGD2 Author keyword 27 43% 5% 48
8 DP1 RECEPTOR Author keyword 27 83% 1% 15
9 BETA TRACE Author keyword 25 73% 2% 19
10 L PGDS Author keyword 17 70% 1% 14

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 CRTH2 90 72% 7% 70 Search CRTH2 Search CRTH2
2 PROSTAGLANDIN D 2 52 38% 10% 108 Search PROSTAGLANDIN+D+2 Search PROSTAGLANDIN+D+2
3 DP RECEPTOR 39 80% 2% 24 Search DP+RECEPTOR Search DP+RECEPTOR
4 LIPOCALIN TYPE PROSTAGLANDIN D SYNTHASE 35 76% 2% 25 Search LIPOCALIN+TYPE+PROSTAGLANDIN+D+SYNTHASE Search LIPOCALIN+TYPE+PROSTAGLANDIN+D+SYNTHASE
5 PROSTAGLANDIN D SYNTHASE 30 55% 4% 37 Search PROSTAGLANDIN+D+SYNTHASE Search PROSTAGLANDIN+D+SYNTHASE
6 PGD2 27 43% 5% 48 Search PGD2 Search PGD2
7 DP1 RECEPTOR 27 83% 1% 15 Search DP1+RECEPTOR Search DP1+RECEPTOR
8 BETA TRACE 25 73% 2% 19 Search BETA+TRACE Search BETA+TRACE
9 L PGDS 17 70% 1% 14 Search L+PGDS Search L+PGDS
10 CRTH2 ANTAGONIST 17 75% 1% 12 Search CRTH2+ANTAGONIST Search CRTH2+ANTAGONIST

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 D SYNTHETASE 161 82% 9% 93
2 PROSTAGLANDIN D 2 RECEPTOR 74 79% 5% 48
3 RECEPTOR CRTH2 69 96% 2% 22
4 CRTH2 69 68% 6% 60
5 D SYNTHASE 65 64% 6% 64
6 BETA TRACE 65 66% 6% 60
7 PROSTANOID DP RECEPTOR 31 74% 2% 23
8 CRTH2 RECEPTOR 24 91% 1% 10
9 PROSTAGLANDIN D 2 22 26% 7% 71
10 DP RECEPTOR 21 71% 2% 17

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Update on the status of DP2 receptor antagonists; from proof of concept through clinical failures to promising new drugs 2014 7 41 80%
Antagonism of the prostaglandin D-2 receptors DP1 and CRTH2 as an approach to treat allergic diseases 2007 128 100 58%
DP2 receptor antagonists in development 2010 34 34 82%
Novel CRTH2 antagonists: a review of patents from 2006 to 2009 2010 28 57 91%
CRTH2 and D-Type Prostanoid Receptor Antagonists as Novel Therapeutic Agents for Inflammatory Diseases 2010 44 139 63%
Prostaglandin D-2 and sleep/wake regulation 2011 29 65 62%
Enzymes of the Cyclooxygenase Pathways of Prostanoid Biosynthesis 2011 69 371 26%
Emerging roles of DP and CRTH2 in allergic inflammation 2006 90 73 68%
Recent Advances in the Discovery and Development of CRTh2 Antagonists 2011 12 27 89%
Biochemical, structural, genetic, physiological, and pathophysiological features of lipocalin-type prostaglandin D synthase 2000 191 94 74%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 MOL BEHAV BIOL 76 47% 12% 119
2 C PIER 13 71% 1.0% 10
3 HUMAN GENE SCI 5 22% 2.0% 21
4 ADV MED DEV 5 34% 1.1% 11
5 OSAKA BIOSCI 3 35% 0.6% 6
6 MENTAL HLTH ENVIRONM EFFECTS 2 40% 0.4% 4
7 UNIT PHYSIOL CHEM 2 16% 1.0% 10
8 ANIM RADIOL 2 33% 0.4% 4
9 SECT CLIN IMMUNOL ALLERGY P DIS 1 33% 0.3% 3
10 BIODEF REGULAT 1 16% 0.6% 6

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000166725 ONO 1301//IP RECEPTOR//EP4 RECEPTOR
2 0.0000141702 CYCLOPENTENONE PROSTAGLANDINS//DELTA12 PROSTAGLANDIN J2//DELTA 12 PROSTAGLANDIN J2
3 0.0000098904 LEUKOTRIENE C 4 SYNTHESIS DEFICIENCY//HADASSAH MED PHARMACOL//EICOSATETRAYNOIC ACID
4 0.0000090219 MPGES 1//PROSTAGLANDIN E SYNTHASE//MPGES 2
5 0.0000085795 ADRENOMEDULLARY OUTFLOW//PROGRAM NEURAL INTEGRAT//BRAIN PHOSPHOLIPASE A2
6 0.0000062273 THROMBOXANE A2 RECEPTOR//THROMBOXANE RECEPTOR//THROMBOXANE A2
7 0.0000058631 NEUROINFLAMMAT S//MOL NEUROSCI UNIT//BUTAPROST
8 0.0000050063 MED BIOCHEM KURAMOTO CHO//4 ACETOXY 2 4 METHYLPHENYLBENZOTHIAZOLE//PHARMACEUT S KITA KU
9 0.0000047295 EXPT THER EUT PHARMACOINFORMAT//PROSTACYCLIN SYNTHASE GENE//PROSTACYCLIN SYNTHASE
10 0.0000046402 POLAROGRAPHIC BEHAVIOR//PUBERTY ADOLESCENCE//SODIUM PENTOBARBITAL INDUCED SLEEP